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CAZyme Information: MGYG000002510_00537
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Klebsiella quasipneumoniae | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella; Klebsiella quasipneumoniae | |||||||||||
| CAZyme ID | MGYG000002510_00537 | |||||||||||
| CAZy Family | GT4 | |||||||||||
| CAZyme Description | D-inositol-3-phosphate glycosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 585633; End: 589274 Strand: - | |||||||||||
Full Sequence Download help
| MRIVIDLQGA QTESRFRGIG RYSIAIARAI IRNNSQHDIF IALSAMLYES IADVKAHFAD | 60 |
| LLPAENIVVW HAAGPVRAMD QGNEWRRESA ELIREAFLES LRPDVVFITS LFEGHVDDAA | 120 |
| TSVHKFSRQY KVAVLHHDLI PLVQAETYLL DDVFKPYYLQ KVEWLKNADL LLTNSAYTAQ | 180 |
| EAIEHLHLQG DHVQNIAAAA DPQFCMAEVT TSEKETVLGH YGIQREFVLY APGGFDSRKN | 240 |
| FKRLIEAYAG LNDALRRTHQ LVIVSKLSIG DRQYLESLAS GNGLQQGELV LTGYVPEHEL | 300 |
| IQLYRLCKLF IFASLHEGFG LPVLEAMSCG APAIGSNVTS IPEVIGNPEA LFDPYSVSSI | 360 |
| RDKIAQCLTD NVFLAHLKEM AQQQARNFSW DKAAVTALEA FEKIATEDSG IAQALPEALI | 420 |
| QKILAISHGQ PDERDLRLCA TAIDYNLKTA ELYQIDDKAL TWRVEGPFDS SYSLALVNRE | 480 |
| FARALSADGV EVLLHSTEGP GDFAPDASFM AQPENSDLLA FYNQCRTRKS NEKIDILSRN | 540 |
| IYPPRVSEMD AKVKLLHCYA WEETGFPQPW INEFNRELDG VLCTSEHVRK VLIDNGLNVP | 600 |
| AFVVGNGCDH WLNTPAETTK NVDDGTFRFL HVSSCFPRKG VQAMLQAWGR AFTRRDNVIL | 660 |
| IIKTFNNPHN EIDAWLAHAQ AQFAEYPKVE VIKEDMSASQ LKGLYESCDV LVAPGCAEGF | 720 |
| GLPIAEAMLS GLPAIVTNWS GQLDFVNSQN SWLVDYQFTR VKTHFGLFSS TWASVDIDNL | 780 |
| TDALKAAAST DKSVLRGMAD SGRELILKQF TWKAVADRSC QAVKTLRAHI DIAQHRARIG | 840 |
| WLTTWNTKCG IATYSQHLVE SAPHGADVVF APQVSAEDLV CADEEFVLRN WIVGKESNYL | 900 |
| ENLQPQIDAL RLNVIVIQFN YGFFNHRELS AFIRRQHDAG RSVVMTMHST VDPLEKEPTW | 960 |
| NFRLAEMAEA LALCDRLLVH SIADMNRLKD LGLTENVALF PHGVINYSAA SVARQPQALP | 1020 |
| LIASYGFCLP HKGLMELVES VHRLKQAGKP VRLRLVNAEY PVGESRDLVA ELKSAAQRLG | 1080 |
| VTDLIEMHND FLPDAESLRL LSEADLLIFA YQNTGESASG AVRYGMATQK PVAVTPLAIF | 1140 |
| DDLDDAVFKF DGCSVDDISQ GIDRILNAIR EQDAWATRTQ QRADAWREQH DYHAVSRRLV | 1200 |
| NMCQGLAKAK YFK | 1213 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT4 | 225 | 371 | 2.1e-28 | 0.9 |
| GT4 | 621 | 755 | 4e-18 | 0.8125 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03822 | GT4_mannosyltransferase-like | 5.02e-108 | 838 | 1198 | 1 | 370 | mannosyltransferases of glycosyltransferase family 4 and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides. |
| cd03809 | GT4_MtfB-like | 4.03e-80 | 2 | 399 | 1 | 362 | glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide. |
| cd03801 | GT4_PimA-like | 1.89e-34 | 18 | 394 | 15 | 358 | phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. |
| COG0438 | RfaB | 6.12e-33 | 15 | 407 | 13 | 380 | Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]. |
| pfam00534 | Glycos_transf_1 | 3.56e-28 | 225 | 384 | 2 | 158 | Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBR82566.1 | 0.0 | 1 | 1213 | 1 | 1213 |
| QPW09443.1 | 0.0 | 1 | 1213 | 1 | 1213 |
| QWA94001.1 | 0.0 | 1 | 1213 | 1 | 1213 |
| BBS48369.1 | 0.0 | 1 | 1213 | 1 | 1213 |
| BAN20053.1 | 0.0 | 1 | 1213 | 1 | 1213 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6KIH_A | 3.88e-07 | 228 | 395 | 247 | 415 | Sucrose-phosphatesynthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_B Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_C Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_D Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_E Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_F Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_G Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_H Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_I Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_J Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_K Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus],6KIH_L Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus [Thermosynechococcus vestitus] |
| 2JJM_A | 2.35e-06 | 297 | 383 | 275 | 363 | CrystalStructure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_B Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_C Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_D Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_E Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_F Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_G Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_H Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_I Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_J Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_K Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_L Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames] |
| 3MBO_A | 2.47e-06 | 297 | 383 | 295 | 383 | CrystalStructure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_B Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_C Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_D Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_E Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_F Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_G Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_H Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis] |
| 5D00_A | 3.92e-06 | 283 | 399 | 254 | 369 | Crystalstructure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate and UMP [Bacillus subtilis subsp. subtilis str. 168],5D00_B Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate and UMP [Bacillus subtilis subsp. subtilis str. 168],5D01_A Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate [Bacillus subtilis subsp. subtilis str. 168],5D01_B Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate [Bacillus subtilis subsp. subtilis str. 168] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A7TZT2 | 8.25e-09 | 110 | 390 | 124 | 421 | Mannosylfructose-phosphate synthase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) OX=176299 GN=mfpsA PE=1 SV=1 |
| A4X1R6 | 5.63e-07 | 168 | 407 | 220 | 469 | D-inositol 3-phosphate glycosyltransferase OS=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) OX=369723 GN=mshA PE=3 SV=1 |
| Q6K973 | 1.77e-06 | 218 | 398 | 564 | 764 | Sucrose synthase 6 OS=Oryza sativa subsp. japonica OX=39947 GN=SUS6 PE=2 SV=1 |
| A5U3B9 | 4.04e-06 | 220 | 398 | 193 | 362 | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) OX=419947 GN=pimC PE=3 SV=1 |
| P0CF99 | 4.04e-06 | 220 | 398 | 193 | 362 | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pimC PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000064 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |