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CAZyme Information: MGYG000003538_00183

You are here: Home > Sequence: MGYG000003538_00183

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA737 sp900769375
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UBA737; UBA737 sp900769375
CAZyme ID MGYG000003538_00183
CAZy Family GT4
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
395 MGYG000003538_46|CGC1 45234.55 9.5944
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003538 1465303 MAG Fiji Oceania
Gene Location Start: 3041;  End: 4228  Strand: -

Full Sequence      Download help

MNLLFYNTAE  RVYRDAEDNL  YVGGNFPDQM  WKRYLNICDK  LTVVMSDCSA  LLSAEEEKIK60
KYPLNTDGFE  LALLPHQYSS  LKAFISPKRR  RSTRKLQEKL  LENADFVIIR  VANSDIIKLC120
RKLNKPYLIE  VVGCPWDAFW  NHSLKGKLIA  PYKFFVAKRN  VKNAPYSLYV  TKKFLQKRYP180
SKNKTMDCSD  VTLNDFDENV  LAERLNKIKN  HNGIFVLGTA  AAVDVKYKGQ  QFVIKALAEL240
KKQGFTNFRY  DIAGGGDPTF  LLKTAREAGV  AEQVNIIGAI  PHEKIFDWLK  TLDMYIQPSL300
QEGLPRSVIE  AMSCAVPCMG  TKIAGLPELI  NERMLFGRKD  IKGIVKLLKT  LTPEDLADLA360
KENFENSKQY  DVALLSKKRA  EFYEDFRRFA  ENYGK395

Enzyme Prediction      help

No EC number prediction in MGYG000003538_00183.

CAZyme Signature Domains help

Created with Snap1939597998118138158177197217237256276296316335355375225351GT4
Family Start End Evalue family coverage
GT4 225 351 1.3e-21 0.80625

CDD Domains      download full data without filtering help

Created with Snap193959799811813815817719721723725627629631633535537556388RfaB65384GT4_PimA-like215349Glyco_trans_1_4117367GT4_WlbH-like225351Glycos_transf_1
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0438 RfaB 1.00e-25 56 388 42 379
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd03801 GT4_PimA-like 1.18e-24 65 384 43 366
phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
pfam13692 Glyco_trans_1_4 2.07e-23 215 349 2 137
Glycosyl transferases group 1.
cd03798 GT4_WlbH-like 6.78e-22 117 367 112 360
Bordetella parapertussis WlbH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
pfam00534 Glycos_transf_1 7.86e-21 225 351 12 141
Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.

CAZyme Hits      help

Created with Snap193959799811813815817719721723725627629631633535537514387QWI24608.1|GT41386AQR95083.1|GT41386EEV38224.1|GT41386AGF56343.1|GT41392AVK50116.1|GT4
Hit ID E-Value Query Start Query End Hit Start Hit End
QWI24608.1 8.15e-110 14 387 12 387
AQR95083.1 2.74e-100 1 386 1 391
EEV38224.1 3.42e-100 1 386 1 383
AGF56343.1 1.10e-99 1 386 1 391
AVK50116.1 2.00e-99 1 392 1 380

PDB Hits      download full data without filtering help

Created with Snap19395979981181381581771972172372562762963163353553752263345D00_A2263322JJM_A2263323MBO_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5D00_A 1.91e-06 226 334 212 317
Crystalstructure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate and UMP [Bacillus subtilis subsp. subtilis str. 168],5D00_B Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate and UMP [Bacillus subtilis subsp. subtilis str. 168],5D01_A Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate [Bacillus subtilis subsp. subtilis str. 168],5D01_B Crystal structure of BshA from B. subtilis complexed with N-acetylglucosaminyl-malate [Bacillus subtilis subsp. subtilis str. 168]
2JJM_A 6.12e-06 226 332 222 325
CrystalStructure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_B Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_C Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_D Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_E Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_F Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_G Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_H Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_I Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_J Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_K Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames],2JJM_L Crystal Structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. [Bacillus anthracis str. Ames]
3MBO_A 6.36e-06 226 332 242 345
CrystalStructure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_B Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_C Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_D Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_E Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_F Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_G Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis],3MBO_H Crystal Structure of the Glycosyltransferase BaBshA bound with UDP and L-malate [Bacillus anthracis]

Swiss-Prot Hits      download full data without filtering help

Created with Snap193959799811813815817719721723725627629631633535537517393sp|P39859|CAPJ_STAAU186334sp|Q46638|AMSK_ERWAM228362sp|Q94BX4|PIGA_ARATH228360sp|P71243|WCAL_ECOLI228356sp|P87172|GPI3_SCHPO
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P39859 2.33e-40 17 393 15 381
Protein CapJ OS=Staphylococcus aureus OX=1280 GN=capJ PE=4 SV=1
Q46638 2.89e-10 186 334 193 348
Amylovoran biosynthesis glycosyltransferase AmsK OS=Erwinia amylovora OX=552 GN=amsK PE=3 SV=2
Q94BX4 1.35e-09 228 362 213 355
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A OS=Arabidopsis thaliana OX=3702 GN=PIGA PE=2 SV=1
P71243 1.56e-07 228 360 235 376
Putative colanic acid biosynthesis glycosyltransferase WcaL OS=Escherichia coli (strain K12) OX=83333 GN=wcaL PE=3 SV=2
P87172 1.73e-07 228 356 203 332
Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpi3 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000057 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003538_00183.