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CAZyme Information: MGYG000000898_00425

You are here: Home > Sequence: MGYG000000898_00425

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA5394 sp900542615
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; UBA5394; UBA5394 sp900542615
CAZyme ID MGYG000000898_00425
CAZy Family GT51
CAZyme Description Monofunctional biosynthetic peptidoglycan transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
998 MGYG000000898_8|CGC1 110789.54 4.5206
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000898 2143386 MAG Denmark Europe
Gene Location Start: 18722;  End: 21718  Strand: -

Full Sequence      Download help

MEHFDGHGPE  ETGLQPMPDP  MDGGQYDRQE  DTPKKNFWET  CRAWLTECWY  RLQGWWMKLR60
RRRHAAQDLD  QELFVERRGN  RSFLLAVLFT  TLKVFVVMVI  LLGCVGMGLV  MGIAKAYIDT120
TPELDTAQIT  KSDKTSYIYD  KDGNLITTFA  GMEYRDWADI  DEIPDMLKNA  LIAIEDVRFY180
KHDGVDYKRL  FSAVINTLRN  ADTHGGSTLT  QQLIKNKVLS  SEQSYKRKIK  EAYLAIELEN240
EFTKDQILEA  YMNDVSLGGS  NYGFKTAAMD  YFGKEMDQLT  IRECAMLAGM  VQQPYNTNPR300
LNIYQRTLTD  AKREELEELY  ASGAITEAQY  RYSLDNNNQM  YVTDRRTNVV  LLAMYEGGFI360
TKDQYEAAMQ  DTVTVVEESS  NNQLYDMPYF  VEYAIKDVVT  HLLEQREMLD  TKTNRAAIEN420
ELRTGGYHIY  LTVDTEMQHT  LQETITNWDE  YPELTDPSAA  VRVETLDNGD  TVETPQPQVA480
AVIFDYHTGE  LRAIVGGREE  PTIQKGLNRA  TSPVQVGSSI  KPLAVYGPAL  DLGASPATIL540
KNFPTPIEGW  DSEKGYPAVG  SEKYLGPLPL  RTGVVQSLNV  AAARTLLEHV  TIPKGAEYLA600
NLGVDQSRIS  ATGSGLALGT  TDITTVEMAA  AYGAIGNGGE  YIEPLSFVRV  VDDNGKVILD660
AESVRERHQV  FKKSTAYMLV  DILTDAVQRG  TGTKAKISGM  TVAGKTGTNS  DYSSVCFSGI720
TPYYSATVWI  GHDYYSQYKL  KGKATGGSYA  APLWQAFMSE  IHEGLTDRPI  IDESPTELGL780
EKCTVCSVSG  LLATEACYAD  SAGHVPITDW  FAEGTAPVAY  CDMHVMSGIC  LDTGQPASAY840
CPRVSNAASV  VLIFQDSMYA  DVVGEVDAYG  NSEGLQILRQ  YIPNAVYVQA  DTDSYNAAIS900
TTGGTCSLHT  PTWMQQNSWD  SSLTTARQNA  QTLITQVNQY  LSQVQTLPDS  DRNTLLQQIN960
TLQSQISYGT  ASNILRTVEE  LQYTYNALRE  AYPPVGAY998

Enzyme Prediction      help

No EC number prediction in MGYG000000898_00425.

CAZyme Signature Domains help

Created with Snap4999149199249299349399449499548598648698748798848898948142303GT51
Family Start End Evalue family coverage
GT51 142 303 9.9e-60 0.9096045197740112

CDD Domains      download full data without filtering help

Created with Snap4999149199249299349399449499548598648698748798848898948154764PBP_1a_fam77783MrcB92828MrcA92835mrcA142302Transgly
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 2.09e-172 154 764 1 531
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 2.14e-160 77 783 4 618
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 6.16e-140 92 828 5 775
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
PRK11636 mrcA 3.97e-69 92 835 7 845
penicillin-binding protein 1a; Provisional
pfam00912 Transgly 4.61e-66 142 302 1 161
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits      help

Created with Snap499914919924929934939944949954859864869874879884889894882859QUA52775.1|GT5182852QUC66968.1|GT5182852QTE72383.1|GT5182852QTE73372.1|GT5168972QTE69475.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
QUA52775.1 1.32e-241 82 859 99 856
QUC66968.1 1.84e-240 82 852 110 860
QTE72383.1 1.77e-239 82 852 110 860
QTE73372.1 1.77e-239 82 852 110 860
QTE69475.1 5.13e-236 68 972 76 941

PDB Hits      download full data without filtering help

Created with Snap49991491992492993493994494995485986486987487988488989481348277U4H_A1387704OON_A1387383DWK_A1387382OLU_A1347643UDF_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7U4H_A 8.03e-77 134 827 19 817
ChainA, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX],7U4H_B Chain B, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX]
4OON_A 8.11e-60 138 770 23 728
Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
3DWK_A 3.54e-56 138 738 10 563
ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A 1.01e-52 138 738 19 572
StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3UDF_A 3.33e-51 134 764 19 718
ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap499914919924929934939944949954859864869874879884889894892824sp|Q0TNZ8|PBPA_CLOP192829sp|Q0SRL7|PBPA_CLOPS98824sp|Q891X1|PBPA_CLOTE112852sp|A5I6G4|PBPA_CLOBH112852sp|A7FY32|PBPA_CLOB1
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q0TNZ8 3.50e-106 92 824 28 724
Penicillin-binding protein 1A OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=pbpA PE=3 SV=1
Q0SRL7 5.38e-106 92 829 28 729
Penicillin-binding protein 1A OS=Clostridium perfringens (strain SM101 / Type A) OX=289380 GN=pbpA PE=3 SV=1
Q891X1 3.74e-105 98 824 26 713
Penicillin-binding protein 1A OS=Clostridium tetani (strain Massachusetts / E88) OX=212717 GN=pbpA PE=3 SV=1
A5I6G4 9.40e-103 112 852 33 730
Penicillin-binding protein 1A OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) OX=441771 GN=pbpA PE=3 SV=1
A7FY32 9.40e-103 112 852 33 730
Penicillin-binding protein 1A OS=Clostridium botulinum (strain ATCC 19397 / Type A) OX=441770 GN=pbpA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000017 0.000016 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
83 105