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CAZyme Information: MGYG000001524_00031

You are here: Home > Sequence: MGYG000001524_00031

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species RUG013 sp001486445
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; RUG013; RUG013 sp001486445
CAZyme ID MGYG000001524_00031
CAZy Family GT51
CAZyme Description Monofunctional biosynthetic peptidoglycan transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
751 79848.42 4.5214
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001524 2090171 Isolate not provided not provided
Gene Location Start: 18612;  End: 20867  Strand: +

Full Sequence      Download help

MASRALKNRP  GTRNRRRYIP  VLYIVVAFAA  LIIAGCCATY  ALASSWLEDL  PDYQDASSYN60
LAQKTRVYAN  DGTTLLAEFY  LENREPVSNL  SDISPYVTQG  TVATEDERFY  QHHGVDPIGI120
ARAVVNNVAG  GSTEGASTLT  QQFVRNTVLS  DEMSEQTLKR  KVREGYIALK  LEESYSKDDI180
LLMYLNTVNY  GSGAYGIEAA  AKKYYSVDAS  DLTLAQAALL  VGIPQSPTYN  NPINYPDNAL240
SRRNTVLARM  LSNNVITQDQ  YDEAVSEPLN  LKVTETTESG  IYKYPYFTSY  VRQVLLDQYS300
EAEVFKGGLT  VTTTLDVKAQ  AAAEKAAARE  DKQVDKDVEA  ALVAVEPSTG  YIRALVGGRD360
YNANEYNLAT  QAQRQAGSSF  KTFTLAAAIE  NGIDPNKTYV  DCNSPATIDM  GEHAQAWTVE420
NYGGHNYGTL  SLADAFALSS  NTGFARLVTA  IGSDKVVDIA  HRMGIESDLQ  SVPSITLGTQ480
GVTVREMAGA  YGTIATGGIQ  HDAVAVEKIT  DANGKVIFQA  DTTGTRVISE  ETAHALEKVM540
EGVVTKGTGK  AAALDNGQTV  AGKTGTSQNW  RDKWFVGITP  QYAVACWEGA  REERQMSSSY600
DASDMFSDFL  NQLLSSSKTE  SFPMDAASDP  TWRTLSSDEQ  DTLGATSYSG  LASGPFSAYS660
SSTSDSDESS  SSSSSSKSSK  SSKSSKSSRS  SASDSSSSSS  SSSSEGSTSS  KSSSSSESSS720
GSASGEGTDG  GGGSSSGSSG  DDEAPSNPYA  R751

Enzyme Prediction      help

No EC number prediction in MGYG000001524_00031.

CAZyme Signature Domains help

Created with Snap377511215018722526230033737541345048852556360063867571374250GT51
Family Start End Evalue family coverage
GT51 74 250 4e-66 0.9774011299435028

CDD Domains      download full data without filtering help

Created with Snap37751121501872252623003373754134504885255636006386757139623MrcB83614PBP_1a_fam21589MrcA26627PbpC74251Transgly
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0744 MrcB 0.0 9 623 2 606
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074 PBP_1a_fam 0.0 83 614 1 529
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009 MrcA 4.62e-161 21 589 5 690
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
COG4953 PbpC 6.86e-82 26 627 7 575
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
pfam00912 Transgly 7.38e-82 74 251 3 177
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits      help

Created with Snap37751121501872252623003373754134504885255636006386757131648ACU93960.1|GT511644BAN76260.1|GT511644BCS56425.1|GT511644BCA87848.1|GT511654QOS67485.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
ACU93960.1 0.0 1 648 1 642
BAN76260.1 6.29e-217 1 644 1 646
BCS56425.1 6.29e-217 1 644 1 646
BCA87848.1 1.49e-213 1 644 1 646
QOS67485.1 5.14e-209 1 654 1 681

PDB Hits      download full data without filtering help

Created with Snap3775112150187225262300337375413450488525563600638675713585893UDF_A1026195FGZ_A1026193VMA_A1026193FWL_A665894OON_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3UDF_A 2.75e-69 58 589 14 687
ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
5FGZ_A 7.83e-66 102 619 173 696
E.coli PBP1b in complex with FPI-1465 [Escherichia coli K-12],5HL9_A E. coli PBP1b in complex with acyl-ampicillin and moenomycin [Escherichia coli K-12],5HLA_A E. coli PBP1b in complex with acyl-cephalexin and moenomycin [Escherichia coli K-12],5HLB_A E. coli PBP1b in complex with acyl-aztreonam and moenomycin [Escherichia coli K-12],5HLD_A E. coli PBP1b in complex with acyl-CENTA and moenomycin [Escherichia coli K-12],6YN0_A Structure of E. coli PBP1b with a FtsN peptide activating transglycosylase activity [Escherichia coli K-12],7LQ6_A Chain A, Penicillin-binding protein 1B [Escherichia coli K-12]
3VMA_A 1.08e-65 102 619 194 717
CrystalStructure of the Full-Length Transglycosylase PBP1b from Escherichia coli [Escherichia coli K-12]
3FWL_A 6.60e-63 102 619 177 700
CrystalStructure of the Full-Length Transglycosylase PBP1b from Escherichia coli [Escherichia coli]
4OON_A 4.69e-60 66 589 22 694
Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits      download full data without filtering help

Created with Snap377511215018722526230033737541345048852556360063867571327614sp|P70997|PBPG_BACSU18611sp|Q68VU2|PBPA_RICTY28611sp|Q9ZCE9|PBPA_RICPR18611sp|Q4UK08|PBPA_RICFE18611sp|Q92G78|PBPA_RICCN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P70997 1.06e-89 27 614 24 608
Penicillin-binding protein 2D OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpG PE=2 SV=3
Q68VU2 2.23e-87 18 611 2 714
Penicillin-binding protein 1A OS=Rickettsia typhi (strain ATCC VR-144 / Wilmington) OX=257363 GN=mrcA PE=3 SV=1
Q9ZCE9 2.32e-87 28 611 12 714
Penicillin-binding protein 1A OS=Rickettsia prowazekii (strain Madrid E) OX=272947 GN=mrcA PE=3 SV=1
Q4UK08 6.62e-87 18 611 2 714
Penicillin-binding protein 1A OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=mrcA PE=3 SV=1
Q92G78 1.28e-86 18 611 2 714
Penicillin-binding protein 1A OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=mrcA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.730189 0.030023 0.233752 0.000234 0.000198 0.005611

TMHMM  Annotations      download full data without filtering help

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