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CAZyme Information: MGYG000002946_00888

You are here: Home > Sequence: MGYG000002946_00888

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Enterocloster sp900555905
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Enterocloster; Enterocloster sp900555905
CAZyme ID MGYG000002946_00888
CAZy Family GT51
CAZyme Description Penicillin-binding protein 1A
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
897 98157.22 5.1828
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002946 4682631 MAG United States North America
Gene Location Start: 9388;  End: 12081  Strand: -

Full Sequence      Download help

MNYGKYETER  RLKSLHSKSA  KYTSKLFLNI  FKALFVLFLF  CVVVGASIGF  GMVKGIIDNA60
PTVDILNIQP  DRFATTIYDA  KGNLTDTLVT  SGSNREAATY  DELPPDLVNA  FVAIEDSRFW120
SHNGIDIRSI  ARAAKGLISD  DYAGGGSTIT  QQLIKNNVFA  GGMESGWGPR  IERKLQEQFL180
AVQLEKNSGM  SKEDTKKQII  TSYLNTINLG  SNTLGVKVAA  RRYFNKEVSD  LTLSECAVLA240
SITKNPSRLN  PITGAEANAE  RRAIVLQYMF  EQDYISKDQQ  EKALADDVYS  RIQNVDAVKK300
ESVTPYSYFT  DELIEQVIQD  LMEKLDYTES  QASNLLYSGG  LQIYTTQNPD  IQAIVDEEIN360
NPDNYDAAKY  SMEYRLSVTH  ANGETQHYSN  KNVEAWRKSV  LGDKNFNGLY  TSTEALQQDI420
DQYKTWLLKE  GDEIIGERLN  TNLQPQASFV  LLDQHTGEVI  AISGGRGEKK  DSLTLNRATN480
VPRQPGSTFK  VISAFAPALD  ACGATLGTVY  YDAPYTVGTK  SFRNWWGESR  GYTGYSSIRD540
GIIYSMNIVA  VRCLMETVTP  QLGVEYAENM  GISTMTKTDL  GAATALGGLT  LGTTNLDLTA600
AYASIANGGV  YIRPRFYTKI  LDHNGKVLID  NQPETRQVLK  DSTAFLLTDA  MTDVMKGNRK660
FMRPGVSPIS  ATGTAAALNN  MSAAGKSGTT  NNNVDVWFEG  FTPYYTAGIW  GGCDSNQKLK720
DGNVNNGGTS  FHKAIWRKIM  NRVHEGLSDP  GFVIPDSIET  AQICRKSGKR  AVSGVCDHDP780
RGNAVYTEYF  AKGTAPTEVC  DKHVSVTVCA  ESGMRPTPFC  PEKTTRICMV  LPSGEDGPTD840
DSYYAIPGEC  PLHTDASTII  VPPAESNGGD  SPGYETPLGP  GYQPSREPSS  EYGPGVQ897

Enzyme Prediction      help

No EC number prediction in MGYG000002946_00888.

CAZyme Signature Domains help

Created with Snap448913417922426931335840344849353858362767271776280785291269GT51
Family Start End Evalue family coverage
GT51 91 269 5.6e-55 0.943502824858757

CDD Domains      download full data without filtering help

Created with Snap448913417922426931335840344849353858362767271776280785294746PBP_1a_fam21756MrcB30825MrcA32808mrcA94269Transgly
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 2.47e-155 94 746 1 531
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 4.35e-152 21 756 5 609
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 2.81e-132 30 825 4 788
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
PRK11636 mrcA 5.09e-68 32 808 5 840
penicillin-binding protein 1a; Provisional
pfam00912 Transgly 4.51e-65 94 269 12 176
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits      help

Created with Snap44891341792242693133584034484935385836276727177628078521895ANU50131.1|GT511895QQR00966.1|GT511895QIX89332.1|GT511895ASN95571.1|GT511895QRP39738.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
ANU50131.1 0.0 1 895 1 893
QQR00966.1 0.0 1 895 1 893
QIX89332.1 0.0 1 895 1 893
ASN95571.1 0.0 1 895 1 893
QRP39738.1 0.0 1 895 1 893

PDB Hits      download full data without filtering help

Created with Snap4489134179224269313358403448493538583627672717762807852577987U4H_A717433DWK_A1007463UDF_A777994OON_A597122OLU_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7U4H_A 5.18e-87 57 798 7 809
ChainA, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX],7U4H_B Chain B, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX]
3DWK_A 8.92e-49 71 743 4 588
ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
3UDF_A 1.36e-48 100 746 44 718
ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
4OON_A 6.35e-46 77 799 23 771
Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
2OLU_A 2.06e-45 59 712 2 565
StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap448913417922426931335840344849353858362767271776280785225821sp|A5I6G4|PBPA_CLOBH25821sp|A7FY32|PBPA_CLOB125821sp|A7GHV1|PBPA_CLOBL51847sp|A0PZT1|PBPA_CLONN9806sp|Q891X1|PBPA_CLOTE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A5I6G4 4.49e-103 25 821 14 720
Penicillin-binding protein 1A OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) OX=441771 GN=pbpA PE=3 SV=1
A7FY32 4.49e-103 25 821 14 720
Penicillin-binding protein 1A OS=Clostridium botulinum (strain ATCC 19397 / Type A) OX=441770 GN=pbpA PE=3 SV=1
A7GHV1 5.85e-103 25 821 14 720
Penicillin-binding protein 1A OS=Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) OX=441772 GN=pbpA PE=3 SV=1
A0PZT1 4.79e-102 51 847 47 781
Penicillin-binding protein 1A OS=Clostridium novyi (strain NT) OX=386415 GN=pbpA PE=3 SV=1
Q891X1 1.37e-100 9 806 6 716
Penicillin-binding protein 1A OS=Clostridium tetani (strain Massachusetts / E88) OX=212717 GN=pbpA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999977 0.000049 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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