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CAZyme Information: MGYG000004124_00347

You are here: Home > Sequence: MGYG000004124_00347

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; QAKW01; QAKW01;
CAZyme ID MGYG000004124_00347
CAZy Family GT51
CAZyme Description Monofunctional biosynthetic peptidoglycan transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
898 99079.19 4.768
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004124 1823169 MAG United Kingdom Europe
Gene Location Start: 17087;  End: 19783  Strand: +

Full Sequence      Download help

MFKKFLAKLI  RKYERRKSEK  AKIISEQTKG  ESTQPKTDKT  IVMNRDLFFK  QIDERKSDHE60
TKTDLPFADI  HPGNTNDIPF  DSDNPDITKI  TDITDVAGTT  KITELSSLAQ  EPSQNEDNKT120
ELKDRKNKEK  KKSPLRRGVW  AVCLTMILTG  VFTMSVFLWY  VFVYVDGEFD  LSYLDNSLNY180
TTVLYGKQDG  KDVEIEQLHG  IENRIWANID  EIPKNMQNAV  IAIEDERFYK  HNGVDLKRTA240
HAVLNFFNPG  STSSFGGSTI  TQQLVKNLTD  DDDHTITRKI  QEMRRAWYLE  SQYKKDQILE300
VYLNTIYLSQ  GCYGVQTASN  RYFGKDVKDL  TLAECACLAS  ITKSPSTYDP  ITNMEKNKER360
AANVLNKMLE  LGFISQEEAE  AAKNEQITIS  DGSNTGTNSA  SVKSYYVDAV  TESVINDLIN420
IKGYSEVYAE  TLVYSGGLQI  FTPYESDIQK  CVDSVYNDPD  NFPKISAKDK  DGNTVTPQSA480
MAVIDNSTGG  VVAIAGGIGE  KTTARGQNRA  TMTYRQPGSS  IKPLSTYAPG  IEYGVSVDGN540
NALSPSSMIL  DWYIDEAKQY  PKNQSRYESN  KKVTLQAGVA  QSLNTVAARV  NVAVGFKRSI600
NFMIDNLGFT  SLVTSDMDRA  HNDENVAALG  LGGLTKGVNV  VEMAAAYASF  PNDGTYTKPY660
FYTKVVDQNG  RVLLENKVES  HTAMTAETAR  VMNSLLSYAA  SSGTGTPANF  GTTEVAGKTG720
TTSDDYDRWF  AGYTSYYTGV  VWYGYDYNKT  VYYSGANPAA  TTWKKVMSKI  HNGLAYKALT780
KPTTLVSAEY  CFDTGMLLTE  NCPNKATGSF  LPDGVPTEPC  TLHTAPAEEV  PSETPGDQTT840
TPGTDTENPP  ADTNTPDSEQ  PSEGNENTNP  DSGNNTDTGQ  NTPQPPEKEP  DQNATNPW898

Enzyme Prediction      help

No EC number prediction in MGYG000004124_00347.

CAZyme Signature Domains help

Created with Snap4489134179224269314359404449493538583628673718763808853197368GT51
Family Start End Evalue family coverage
GT51 197 368 1.8e-66 0.9548022598870056

CDD Domains      download full data without filtering help

Created with Snap4489134179224269314359404449493538583628673718763808853203771PBP_1a_fam134782MrcB139844MrcA202369Transgly204770PbpC
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 1.49e-174 203 771 1 529
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 1.22e-163 134 782 8 608
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 1.53e-124 139 844 8 793
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912 Transgly 1.58e-79 202 369 11 177
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG4953 PbpC 2.71e-61 204 770 58 561
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Created with Snap4489134179224269314359404449493538583628673718763808853166777AUO18445.1|GT51128824QNL43378.1|GT51127823BAK99350.1|GT51142823QUO37805.1|GT51138823ALP94484.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
AUO18445.1 7.93e-158 166 777 39 640
QNL43378.1 4.27e-156 128 824 19 710
BAK99350.1 3.88e-151 127 823 14 732
QUO37805.1 6.90e-148 142 823 36 747
ALP94484.1 8.39e-147 138 823 32 729

PDB Hits      download full data without filtering help

Created with Snap44891341792242693143594044494935385836286737187638088531958187U4H_A2898153ZG8_B2898153ZG7_B2118164OON_A2087703DWK_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7U4H_A 1.03e-74 195 818 31 809
ChainA, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX],7U4H_B Chain B, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX]
3ZG8_B 3.03e-67 289 815 3 499
CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B 9.54e-61 289 815 3 499
CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
4OON_A 7.23e-50 211 816 46 768
Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
3DWK_A 7.99e-50 208 770 31 588
ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]

Swiss-Prot Hits      download full data without filtering help

Created with Snap4489134179224269314359404449493538583628673718763808853189824sp|Q891X1|PBPA_CLOTE128824sp|Q0SRL7|PBPA_CLOPS128824sp|Q0TNZ8|PBPA_CLOP1182823sp|A7FY32|PBPA_CLOB1182823sp|A5I6G4|PBPA_CLOBH
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q891X1 1.04e-96 189 824 65 714
Penicillin-binding protein 1A OS=Clostridium tetani (strain Massachusetts / E88) OX=212717 GN=pbpA PE=3 SV=1
Q0SRL7 1.43e-94 128 824 12 725
Penicillin-binding protein 1A OS=Clostridium perfringens (strain SM101 / Type A) OX=289380 GN=pbpA PE=3 SV=1
Q0TNZ8 6.52e-94 128 824 12 725
Penicillin-binding protein 1A OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=pbpA PE=3 SV=1
A7FY32 4.65e-93 182 823 57 702
Penicillin-binding protein 1A OS=Clostridium botulinum (strain ATCC 19397 / Type A) OX=441770 GN=pbpA PE=3 SV=1
A5I6G4 4.65e-93 182 823 57 702
Penicillin-binding protein 1A OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) OX=441771 GN=pbpA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999681 0.000312 0.000014 0.000001 0.000000 0.000001

TMHMM  Annotations      download full data without filtering help

start end
139 161