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CAZyme Information: MGYG000004170_00540

You are here: Home > Sequence: MGYG000004170_00540

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-710;
CAZyme ID MGYG000004170_00540
CAZy Family GT51
CAZyme Description Monofunctional biosynthetic peptidoglycan transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
951 MGYG000004170_2|CGC2 105787.09 9.2845
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004170 1128310 MAG United Kingdom Europe
Gene Location Start: 47755;  End: 50610  Strand: -

Full Sequence      Download help

MTNKNIKVKQ  NQKRRNTSQN  KKNVKFNTDT  LICIALVILM  LILGIKLLGV  KTGIIFTLIL60
FGGIALILFL  SKIIGKIGKN  KKSRKIINVI  VIILLVLCIA  GCVGVCSFFL  YIVEKAPEFD120
EKQLVYSEST  LLYDKDNKLV  TELGAKKREN  ITYDEMSEVL  IDAMIATEDS  RFFQHNGFDA180
ARFLKASFGQ  VINKLLHRSS  NAGGASTLSM  QVVKNSFTSK  EAEGWEGIVR  KFTDIYLSVF240
KLEKNYTKQE  IIEFYANNHF  LGANSYGVEQ  AARTYFGKHA  SELNLAEASL  IVGIFKAPTS300
YNPFNYPEAA  TARRKTVLNL  MYYHGYITKE  ERDLANSIPV  KSLLVKSNDN  TSEYQGYIDT360
VVAEIEKKWK  VNPYNTPLII  YTNMDTKKQA  EVNKIFTGET  FKWENDYIQA  GIAAVDVHNG420
KIIAIGNGRN  RNGASTYNFA  TDINRQIGSS  AKPVIDYAPG  MEFLNWSTYQ  IFDDSKHYYS480
SGQEIRDADR  RYMGNITLRT  ALAQSRNIPA  LKAFQAVMKE  IGSAKYKEFV  QSFGIKTENY540
LHEAHAIGSF  NGSNPLTMAS  AYAVFANGGY  YYQPYSVNKI  VFRNTGETVE  YKSEGKQVIS600
DSTAFMITDV  LVSAVQNGLS  SGARISGYNI  AAKTGTTNYD  EAAIKATGVP  RNAIPDAWLI660
GYNSDVSIGV  WYGCELPSKT  KYLTQNSGII  YRGKLFRAAA  QITMNKGTTF  DVPNSVVKVG720
IEKGSNPAKL  ASSSTPSDNI  VYEYFKKGTE  PTEVSIKYSK  LPNVTGLTGE  YNASDLSFTL780
NWSAIKLENP  ANETEYGKLG  YKIYKDNKLI  KFTTDTSYTF  LNVTDPRGTY  KVVTTYKNFS840
DNESTGATYK  YAVNSEDVFT  AKLKYQSSSY  ENGDTLATFD  KSPSSADITV  HLNGEDITAK900
SNITVTITDP  NGNVVTTVDN  NVIGTFTIKY  NVKYETHSEE  LIRTITISEK  S951

Enzyme Prediction      help

No EC number prediction in MGYG000004170_00540.

CAZyme Signature Domains help

Created with Snap4795142190237285332380427475523570618665713760808855903137322GT51
Family Start End Evalue family coverage
GT51 137 322 5.7e-54 0.9887005649717514

CDD Domains      download full data without filtering help

Created with Snap4795142190237285332380427475523570618665713760808855903147673PBP_1a_fam108752MrcB101753MrcA136688PBP_1b136322Transgly
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 1.56e-156 147 673 1 500
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 1.69e-145 108 752 34 650
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 3.66e-104 101 753 19 766
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
TIGR02071 PBP_1b 4.69e-64 136 688 132 670
penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam00912 Transgly 3.03e-62 136 322 1 177
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits      help

Created with Snap479514219023728533238042747552357061866571376080885590398847AWI12666.1|GT51109812APH04640.1|GT51103786QOR68963.1|GT51101857QNU34821.1|GT51101857QSB47366.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
AWI12666.1 7.00e-164 98 847 45 772
APH04640.1 1.38e-162 109 812 54 747
QOR68963.1 1.20e-161 103 786 2 675
QNU34821.1 1.83e-159 101 857 46 764
QSB47366.1 1.83e-159 101 857 46 764

PDB Hits      download full data without filtering help

Created with Snap47951421902372853323804274755235706186657137608088559031327343DWK_A1157342OLU_A2416873ZG8_B2416873ZG7_B1325875U2G_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3DWK_A 2.07e-89 132 734 10 614
ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A 5.86e-87 115 734 2 623
StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3ZG8_B 6.18e-54 241 687 2 445
CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B 8.15e-50 241 687 2 445
CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
5U2G_A 6.16e-46 132 587 24 561
2.6Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20],5U2G_B 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20]

Swiss-Prot Hits      download full data without filtering help

Created with Snap479514219023728533238042747552357061866571376080885590399783sp|P39793|PBPA_BACSU107673sp|Q00573|PBPA_STROR109673sp|Q04707|PBPA_STRPN109734sp|Q8DR59|PBPA_STRR6107740sp|A0A0H2ZMF9|PBP2A_STRP2
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P39793 8.01e-145 99 783 46 728
Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q00573 2.85e-96 107 673 30 599
Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
Q04707 8.02e-93 109 673 32 598
Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59 2.15e-92 109 734 32 658
Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
A0A0H2ZMF9 4.07e-68 107 740 70 692
Penicillin-binding protein 2a OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) OX=373153 GN=pbp2a PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000011 0.000026 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
23 45
55 77
90 112