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CAZyme Information: MGYG000001533_00214

You are here: Home > Sequence: MGYG000001533_00214

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Corynebacterium ammoniagenes
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium ammoniagenes
CAZyme ID MGYG000001533_00214
CAZy Family GT53
CAZyme Description putative arabinosyltransferase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1131 MGYG000001533_1|CGC1 123303.49 4.2841
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001533 2790185 Isolate not provided not provided
Gene Location Start: 197352;  End: 200747  Strand: -

Full Sequence      Download help

MNDVYTAELP  ELSARPAPKG  LRLAAIITGL  IGFVLFLATP  FLPVTQTQSS  FDWPREDSLN60
SVTAPLISVS  PEEIDATIPV  AATDMLRDGQ  DLLYATVPPE  SEEASNRGMF  VRAGEQGLSV120
ISLDEVVLSL  SEEQVQELSD  DDEITIHSTE  DATTVSVGEY  SEKSTEDLRP  QVVGVFTEIE180
DTPENLEQLS  EAGLNVHVDI  NSRFTSSPTT  IKLVAMIGGL  IMMLAALVCI  ARLDRLDGKK240
ISFMPATWKQ  IRPLDGVVSA  VLVFWHIFGA  NTSDDGFILT  MGRVKEHATY  MANYYRWYGV300
PEAPFGTPYY  DLVALLSNIS  ATSVFMRIPT  LIAAILTWFI  LSREILPRFG  PMINDRRVAH360
WTAAFMFLAF  WLPYNNGIRP  EPIVAFGVIF  TWASFERSIA  TSRMLPAAVG  TIAATLTLTA420
GPTGLLAVGV  FLVSLPALFS  IFSRRKDSAG  GWLPLIAPFL  AVGTSVLALV  FSDQTLATVL480
ESTRVRSAVG  PSLNWYDEYV  RYTTLFEGSV  DGSLTRRFAM  FTMLFALALI  IYAFIRDKKV540
LGTSKGPTQR  LLVIMGLSMF  FLMFTPTKWT  HHFGIYAGIA  GVIAALGAVV  LSQIAMRSPR600
ARTFAVASVV  FLMAISLAGW  NAWWYVSSFG  VPWWDRSVQF  KTIEASTVVM  VIGLIIVAIG660
IVQALRHNYR  KNHGIEQPQV  SAKRWTSILS  APLAIACIAI  VAFSCLSFAK  AYISQSPSYS720
VGQGNLKAIG  GNECQLADAA  LIETNTNESF  LTPVTGDLGE  SLINPEEDNR  GFDPNFIPED780
IEPENLNSAS  VGAIGSTQTG  STSSDSEQAT  SGTDPSLGGQ  TEEQSNASSP  QANAENVTDT840
SSGGIRGTDG  VNGSTMHLPF  NLDYTKVPVL  GSYDTGQRGT  SEVTTQWYNL  PEAPGENTPV900
LSVAAAGDIY  HHDVNDVEQE  GMELTLEYGT  LGEGDEVTNT  GELELRDVGA  SPKWRNLRIA960
LDEIPDDANV  VRLVAVDDST  DEDSWLAFTP  PRVPELTTLN  SQFDSSMPGL  LDWSTAFQFP1020
CQRTFDHFAG  VTEIPEYRIL  PDAPAQNSLT  DFQSFSGGGA  MATAEAVNYS  YEIPSYLDGD1080
WARDWGAIQK  YELRTNSQGV  TPDPADINYE  EITRSGWWQN  SEMKIRKEGE  E1131

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Created with Snap5611316922628233939545250856562267873579184890496110171074211124GT53
Family Start End Evalue family coverage
GT53 21 1124 0 0.9952335557673975

CDD Domains      download full data without filtering help

Created with Snap5611316922628233939545250856562267873579184890496110171074207666Arabinose_trans7061124Arabino_trans_C45203Arabino_trans_N257670ArnT518708SdaC
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 207 666 1 459
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 3.40e-175 706 1124 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 2.59e-51 45 203 1 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
COG1807 ArnT 0.001 257 670 15 411
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
COG0814 SdaC 0.004 518 708 48 252
Amino acid permease [Amino acid transport and metabolism].

CAZyme Hits      help

Created with Snap561131692262823393954525085656226787357918489049611017107411131APT81579.1|GT5311131AQS72703.1|GT5311131AMJ43631.1|GT5311131AQX72304.1|GT5311131AQX70078.1|GT53
Hit ID E-Value Query Start Query End Hit Start Hit End
APT81579.1 0.0 1 1131 1 1131
AQS72703.1 0.0 1 1131 1 1131
AMJ43631.1 0.0 1 1131 1 1131
AQX72304.1 0.0 1 1131 1 1131
AQX70078.1 0.0 1 1131 1 1131

PDB Hits      download full data without filtering help

Created with Snap56113169226282339395452508565622678735791848904961101710742211257BVE_A2211257BVH_A2211267BWR_A2211266X0O_A2211267BVC_B
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7BVE_A 6.75e-264 22 1125 16 1073
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]
7BVH_A 1.67e-263 22 1125 29 1086
Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155]
7BWR_A 1.98e-233 22 1126 27 1081
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
6X0O_A 3.20e-233 22 1126 27 1081
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BVC_B 3.40e-233 22 1126 27 1081
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Created with Snap5611316922628233939545250856562267873579184890496110171074221125sp|Q50393|EMBC_MYCSM91124sp|Q7TVN4|EMBC_MYCBO91124sp|P9WNL5|EMBC_MYCTU91124sp|P9WNL4|EMBC_MYCTO221124sp|Q9CDA7|EMBC_MYCLE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50393 1.90e-260 22 1125 16 1073
Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2
Q7TVN4 5.74e-246 9 1124 14 1092
Probable arabinosyltransferase C OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embC PE=3 SV=1
P9WNL5 3.21e-245 9 1124 14 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embC PE=1 SV=1
P9WNL4 4.52e-245 9 1124 14 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embC PE=3 SV=1
Q9CDA7 1.06e-242 22 1124 12 1069
Probable arabinosyltransferase C OS=Mycobacterium leprae (strain TN) OX=272631 GN=embC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000029 0.000008 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
20 42
209 231
251 270
319 341
358 375
420 442
449 471
518 535
548 565
569 591
604 626
646 665
685 707