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CAZyme Information: MGYG000002486_00849
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Fusobacterium_A varium | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium_A; Fusobacterium_A varium | |||||||||||
| CAZyme ID | MGYG000002486_00849 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 917433; End: 918419 Strand: - | |||||||||||
Full Sequence Download help
| MKILVIRLSS IGDIILTTPV LKAFKEKYPE AVIDFLVLDK FKDSIEGVPF IDNIILFNKE | 60 |
| KNDGLHNMEK FAKELKKNGY DYIFDLHSKI RSKVISKNIG VKTFTYRKRS WWKTLLVKMK | 120 |
| LIKYKVDDTI VKNYFGAFKD FGLEYKGEDI YFAFSEKDKV SKEYEGLPVM APGASKNTKK | 180 |
| WTKEGFGELA NLIYKKYGKN TILIGGKEDI ELCNEIDKIS GGHIVNMAGK LSLKQSGALL | 240 |
| SKALFLVTND SGPFHIARGV KCKTFVIFGP TSSEMFDLDR NTVLIDKNVK CSPCSLHGDK | 300 |
| ECPKGHFDCM KLITGKEVFN IIESSVKI | 328 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 69 | 307 | 2.8e-43 | 0.9733333333333334 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 4.59e-63 | 2 | 323 | 1 | 276 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 1.66e-62 | 1 | 324 | 2 | 328 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| TIGR02195 | heptsyl_trn_II | 6.39e-29 | 2 | 324 | 1 | 331 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| pfam01075 | Glyco_transf_9 | 3.24e-25 | 70 | 306 | 3 | 245 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| PRK10422 | PRK10422 | 2.70e-20 | 2 | 271 | 7 | 291 | lipopolysaccharide core biosynthesis protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVQ30467.1 | 1.41e-239 | 1 | 328 | 1 | 328 |
| VEH40952.1 | 1.41e-239 | 1 | 328 | 1 | 328 |
| BBA49819.1 | 3.21e-220 | 1 | 328 | 1 | 328 |
| SQJ15109.1 | 5.32e-219 | 1 | 328 | 1 | 328 |
| AVQ27557.1 | 5.32e-219 | 1 | 328 | 1 | 328 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3TOV_A | 2.73e-14 | 2 | 324 | 10 | 343 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q57336 | 1.31e-14 | 5 | 257 | 13 | 270 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
| P25742 | 3.57e-13 | 12 | 271 | 5 | 279 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
| Q9R9D5 | 7.48e-11 | 12 | 271 | 5 | 279 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| P37692 | 1.40e-10 | 1 | 274 | 1 | 293 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 1.10e-09 | 1 | 274 | 1 | 293 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000072 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |