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CAZyme Information: MGYG000002505_00156
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Oxalobacter formigenes_B | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; Oxalobacter; Oxalobacter formigenes_B | |||||||||||
| CAZyme ID | MGYG000002505_00156 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 184285; End: 185385 Strand: + | |||||||||||
Full Sequence Download help
| MVFMDKMPAR ILIISPNWIG DAIMAQPLLQ LLKQRDPSAL VDVLAPIWVA PVWEAMTEVG | 60 |
| NVYATPFKHG KLQLRERWSL ARTLRKFAYD QAYVLPNTLK FALIPWMARI PERIGYLGEK | 120 |
| RYGLLNVIHR DNKLSPRPMI PFYAALADPP AAKAGKREDY PRPSLFVAKK EADATLEKWK | 180 |
| VDTSRPIVAF APGAEFGPAK RWPVHGFIDL AQRILSEFPD AQILLLGSPN DRAVCEEIAS | 240 |
| DVPAVKNLAG KTTLKEAIAL ISRIDALVTN DSGLMHVASA FEKPVIALYG STDYRHTPPF | 300 |
| SRYSEILSLD LECAPCQKRE CPLGHHRCME LLRSETVYSA LKKYLVDPAG AAQRPKPDNR | 360 |
| TEKMGC | 366 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 77 | 327 | 3.7e-61 | 0.9822222222222222 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR02195 | heptsyl_trn_II | 5.14e-142 | 10 | 346 | 1 | 334 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK10916 | PRK10916 | 9.94e-97 | 10 | 345 | 2 | 343 | ADP-heptose--LPS heptosyltransferase RfaF. |
| COG0859 | RfaF | 2.67e-83 | 10 | 345 | 3 | 330 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| cd03789 | GT9_LPS_heptosyltransferase | 3.98e-75 | 10 | 343 | 1 | 277 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| pfam01075 | Glyco_transf_9 | 6.18e-60 | 77 | 325 | 1 | 245 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QDX34123.1 | 5.04e-159 | 7 | 343 | 1 | 337 |
| ARQ46794.1 | 5.22e-159 | 7 | 343 | 2 | 338 |
| ARQ78855.1 | 5.22e-159 | 7 | 343 | 2 | 338 |
| BBB67613.1 | 1.48e-141 | 9 | 357 | 10 | 352 |
| BBB61552.1 | 1.97e-139 | 9 | 345 | 10 | 344 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1PSW_A | 2.27e-71 | 10 | 346 | 2 | 344 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P37421 | 2.53e-76 | 10 | 345 | 2 | 343 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| P37692 | 1.01e-75 | 10 | 346 | 2 | 344 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P45042 | 1.84e-69 | 10 | 345 | 2 | 344 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| Q57336 | 4.35e-11 | 1 | 309 | 1 | 301 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000052 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |