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CAZyme Information: MGYG000003795_00803
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Anaeroglobus sp900240295 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Anaeroglobus; Anaeroglobus sp900240295 | |||||||||||
| CAZyme ID | MGYG000003795_00803 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7179; End: 8225 Strand: - | |||||||||||
Full Sequence Download help
| MINLRQKRII VTFLMHLGDL ILVTPFLQVL RRHAHGSEIT LVVDAKVADV VRYNPNIDHL | 60 |
| IEIDKKGRDN SVSALWRIGR KLHRNNYDVL INLHPNERTS FLAVAIQAGY FAGMSHFLAR | 120 |
| PFMDRYTRLD RLHFHAADMY INVLEQLGIE DRRNSGLEIE LAAAWREKAA AFYAEYNREG | 180 |
| RPLVGFNIGS AVPQKRWPPQ RFAAVADYFM DKGYGCVFFG GPMDKEMVAE AVSFMEHKPI | 240 |
| IATGLFSIGE LAAAVKACSL FITNDSGPMH IAVSQQVPLV ALYGPSNPMF YGPYTEKAIV | 300 |
| LESTDHYEVG KSMKKIIREG KYKGISVISV AHVIEAGEEL LKKYGRRL | 348 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 76 | 304 | 3.9e-53 | 0.9022222222222223 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 1.36e-61 | 8 | 336 | 1 | 274 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 1.24e-48 | 7 | 343 | 2 | 332 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 9.30e-37 | 76 | 323 | 2 | 247 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| TIGR02195 | heptsyl_trn_II | 5.00e-28 | 76 | 341 | 69 | 333 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK10422 | PRK10422 | 3.20e-26 | 7 | 342 | 6 | 344 | lipopolysaccharide core biosynthesis protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AXL20515.1 | 3.31e-200 | 1 | 344 | 1 | 345 |
| AXB80808.1 | 2.45e-196 | 1 | 348 | 1 | 349 |
| ALG42175.1 | 1.05e-187 | 1 | 347 | 1 | 349 |
| AVO27634.1 | 2.99e-187 | 1 | 347 | 1 | 349 |
| CCC73399.1 | 2.99e-187 | 1 | 347 | 1 | 349 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3TOV_A | 2.81e-139 | 3 | 341 | 5 | 345 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
| 1PSW_A | 5.84e-19 | 181 | 341 | 180 | 343 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P25742 | 2.72e-23 | 18 | 341 | 5 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
| Q9R9D5 | 3.73e-20 | 18 | 341 | 5 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| P37692 | 4.10e-20 | 18 | 341 | 12 | 343 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 1.43e-19 | 181 | 345 | 180 | 347 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| P45042 | 3.57e-19 | 18 | 343 | 12 | 346 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.970765 | 0.028758 | 0.000289 | 0.000079 | 0.000045 | 0.000082 |