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CAZyme Information: MGYG000001018_00171

You are here: Home > Sequence: MGYG000001018_00171

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mediterraneibacter sp900751785
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter; Mediterraneibacter sp900751785
CAZyme ID MGYG000001018_00171
CAZy Family PL8
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1404 150858.37 3.9263
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001018 2841260 MAG Sweden Europe
Gene Location Start: 10460;  End: 14674  Strand: -

Full Sequence      Download help

MKLKKVNRLL  ALACAAAVTA  SGFCPAAPVK  AKETSGIENA  EISEQQEESG  ISMQAEDSTE60
NMILYWSDDL  EETTAVSGTA  ASYWADGTAA  KNWTGLWQAK  AFTNEKAVIS  LDKETFASGS120
QSVHYSSTDA  SGRISVSLGA  ALQNVDFTKN  YILRAKVKAE  NVTVSGNNGF  YMRGKANNVT180
ITPEGTRVNG  TTDGWITYDV  PLQNLVSVGG  AQSGSLALEI  FFDYLTGDVW  FDSIELWQDY240
QISLSETEKT  IKPGESFQLE  VQCDSEEVDL  SKVTWSSSNP  DAVSVDENGM  ITAEALGTAV300
ITAKLDESHT  ASCTVQVDDP  EMLAPQYAEM  RSRWTERLTG  NGSSITDDED  FQTSMETMAQ360
DAEDAMENMA  DIPADGSHVD  ALWSDLDLEI  KYVATSDASY  TEDLNTAYTR  LQAMATAYAA420
ENCRLYHNED  LKERILYALE  WLYDNGYNEN  YNVEKQLYGN  WWHWEIGIPQ  ALGSTVILMY480
EDLTQEQIDK  FYATLYRFNQ  DPTVVYKVQG  WGTMEMTSAN  LMDTSLVAAL  RSAIGNTQDG540
IGAAVNALGT  VTGFVTEGDG  FYEDGSCIQH  SNLAYTGGYG  LTLLKGIERI  LLLSNDTAWQ600
ASADDLESVY  TWIWEGYRPL  FADGAMMDMV  SGRSIARPSH  TELETGRGIL  EAIVLLADGA660
PDDRKEQLLS  FATKQVLAGA  ENLDTFYSGM  EASSMIAAKQ  LAADDSVEAD  DGTPYTKIFG720
SMDKATIHRE  GYTLGISMFS  SRTGNFEYMN  KENTKGWHIS  DGALFLYNGD  AGQFSNNYWN780
TIDPHRLPGI  TTDHTEGTNY  ESGLAYTSDK  DYAGGSSVED  LYATIAMDFH  GQNTDLTAKK840
AWFAFDDEVV  ALGTDISGIT  KDTETIIENK  QIRDDGSNAL  VVDGEETQAE  LGESSAAGVE900
YAWIEGNSGT  DSIGYYFPEG  EDLEIKREAR  TGSFQDINGA  VADGAAGSED  VTRDYLSLAV960
SHGDGTEEGA  EDYAYVLLPG  RTEEETAEYA  SGSEIEIISN  TAEVQAAADR  SSGASGYQFW1020
TAASAGNVSA  DQASSVTMKE  EDGTLKLGIS  DPSQTQDSVT  IHVSGYKNLQ  YVDGDQEAVV1080
NATEDGVDIT  VDTSAGAGKT  YELTLTYEEE  GAETSVSTAL  LGYAIELAKD  ADLTDVVPAV1140
VEKFNAALSN  AEEIVEKVKA  GDTSITQEMM  DESWQELVRA  MQYLSFKQGD  KTNLNKVIAM1200
AESLDLDGYL  LAGQDVFTEA  LDSARAVAAD  ENAMEKEIEE  AWRELLAAMG  NLRLKPSKEL1260
LEDLISQAQS  VDTAVYTEES  VQALTAALAD  AVAVFDDDQA  DKEQVEEAQS  ALKAALAGLT1320
AKTEAGGSDA  AGADTDTGNS  GTGSAGSGTA  GTVNSSADRA  VKTGDSSPAV  PLYAAAAALA1380
LVCAAGSGLG  KQADRGRKES  KDKE1404

Enzyme Prediction      help

No EC number prediction in MGYG000001018_00171.

CAZyme Signature Domains help

Created with Snap7014021028035142149156163170277284291298210531123119312631333717983PL8
Family Start End Evalue family coverage
PL8 717 983 1.3e-78 0.9884169884169884

CDD Domains      download full data without filtering help

Created with Snap70140210280351421491561631702772842912982105311231193126313333271052GAG_Lyase334671Lyase_8_N716980Lyase_89981060Lyase_8_C241315Big_2
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 0.0 327 1052 2 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam08124 Lyase_8_N 6.37e-83 334 671 1 320
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02278 Lyase_8 1.82e-75 716 980 1 250
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 8.28e-13 998 1060 1 67
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02368 Big_2 8.57e-10 241 315 2 77
Bacterial Ig-like domain (group 2). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial and phage surface proteins such as intimins.

CAZyme Hits      help

Created with Snap70140210280351421491561631702772842912982105311231193126313331061103SQI53822.1|CBM70|PL8641130SYX85126.1|CBM70|PL8681112AZS13398.1|CBM70|PL8791103AYV66165.1|CBM70|PL8791103QJX62049.1|CBM70|PL8
Hit ID E-Value Query Start Query End Hit Start Hit End
SQI53822.1 1.87e-173 106 1103 70 1046
SYX85126.1 9.65e-170 64 1130 33 1095
AZS13398.1 5.85e-165 68 1112 48 1068
AYV66165.1 5.95e-162 79 1103 49 1048
QJX62049.1 7.38e-162 79 1103 44 1043

PDB Hits      download full data without filtering help

Created with Snap701402102803514214915616317027728429129821053112311931263133332611011J0M_A32611012E24_A32611012E22_A32611011X1H_A32411036F2P_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1J0M_A 1.21e-120 326 1101 3 745
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
2E24_A 1.67e-120 326 1101 3 745
ChainA, Xanthan lyase [Bacillus sp. GL1]
2E22_A 8.49e-120 326 1101 3 745
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
1X1H_A 5.96e-119 326 1101 3 745
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]
6F2P_A 3.41e-115 324 1103 3 747
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap70140210280351421491561631702772842912982105311231193126313333261110sp|Q9AQS0|XANLY_BACGL1451013sp|Q54873|HYSA_STRPN591012sp|Q53591|HYSA_STRA3315980sp|Q59801|HYSA_STAA82911105sp|P0CZ01|HYSA_CUTAK
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 2.74e-117 326 1110 28 779
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q54873 2.91e-92 145 1013 121 950
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 9.99e-74 59 1012 9 930
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q59801 1.04e-73 315 980 37 692
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
P0CZ01 1.05e-53 291 1105 11 796
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001345 0.587641 0.408332 0.001905 0.000447 0.000284

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001018_00171.