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CAZyme Information: MGYG000000001_02614

You are here: Home > Sequence: MGYG000000001_02614

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species GCA-900066495 sp902362365
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; GCA-900066495; GCA-900066495 sp902362365
CAZyme ID MGYG000000001_02614
CAZy Family GH18
CAZyme Description Peroxiredoxin
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
583 MGYG000000001_50|CGC1 65045.57 4.611
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000001 3219617 Isolate United Kingdom Europe
Gene Location Start: 2831;  End: 4582  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000001_02614.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 262 562 6.8e-60 0.8851351351351351

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK13189 PRK13189 2.65e-109 3 211 7 220
peroxiredoxin; Provisional
cd03016 PRX_1cys 5.27e-105 7 211 1 203
Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by reducing and detoxifying hydrogen peroxide, peroxynitrite, and organic hydroperoxides. As with all other PRXs, a cysteine sulfenic acid intermediate is formed upon reaction of 1-cys PRX with its substrates. Having no resolving cysteine, the oxidized enzyme is resolved by an external small-molecule or protein reductant such as thioredoxin or glutaredoxin. Similar to typical 2-cys PRX, 1-cys PRX forms a functional dimeric unit with a B-type interface, as well as a decameric structure which is stabilized in the reduced form of the enzyme. Other oligomeric forms, tetramers and hexamers, have also been reported. Mammalian 1-cys PRX is localized cellularly in the cytosol and is expressed at high levels in brain, eye, testes and lung. The seed-specific plant 1-cys PRXs protect tissues from reactive oxygen species during desiccation and are also called rehydrins.
cd06548 GH18_chitinase 2.04e-84 257 551 15 322
The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.
COG0450 AhpC 4.25e-76 1 172 1 174
Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms].
PRK13190 PRK13190 2.57e-73 7 209 4 200
putative peroxiredoxin; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QJA08894.1 0.0 1 579 1 579
CED94343.1 0.0 1 581 1 588
CEI73471.1 0.0 1 576 1 583
QYE99248.1 8.85e-311 1 580 1 584
AXU45984.1 3.16e-310 1 581 1 709

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6TSB_AAA 2.22e-190 229 581 15 367
ChainAAA, Peroxiredoxin [Clostridioides difficile 630]
6T9M_AAA 4.41e-190 229 581 34 386
ChainAAA, Peroxiredoxin [Clostridioides difficile 630]
5OVQ_D 2.00e-79 3 208 5 218
CrystalStructure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_F Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_G Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_H Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_I Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_J Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_L Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5]
5OVQ_A 2.07e-79 3 208 5 218
CrystalStructure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_B Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_C Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_E Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_K Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5]
6Q5V_A 1.64e-61 4 209 6 209
1-CysSiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_B 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_C 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_D 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_E 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_F 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_G 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_H 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_I 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_J 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8R844 5.82e-95 4 209 14 218
Peroxiredoxin 2 OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE2186 PE=3 SV=1
O67024 3.58e-80 3 208 5 218
Peroxiredoxin OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_858 PE=1 SV=1
Q8PYP6 1.11e-64 4 208 1 212
Peroxiredoxin OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0814 PE=3 SV=1
Q58146 2.87e-64 4 209 1 213
Peroxiredoxin OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ0736 PE=3 SV=2
Q74NC6 1.83e-63 7 208 4 217
Peroxiredoxin OS=Nanoarchaeum equitans (strain Kin4-M) OX=228908 GN=NEQ191 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000060 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000001_02614.