dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000002_01013

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Basic Information help

Species

Blautia_A faecis

Lineage

Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A faecis

CAZyme ID

MGYG000000002_01013

CAZy Family

GH25

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
525	MGYG000000002_3\|CGC4	58910.66	9.7564

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000002	4433109	Isolate	United Kingdom	Europe

Gene Location

Start: 189317; End: 190894 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000002_01013.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH25	88	266	8.8e-45	0.9943502824858758

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06414	GH25_LytC-like	2.20e-56	86	288	2	191	The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
cd00599	GH25_muramidase	3.60e-26	86	285	1	184	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
pfam01183	Glyco_hydro_25	1.72e-23	89	265	2	179	Glycosyl hydrolases family 25.
cd06413	GH25_muramidase_1	5.06e-19	85	285	3	187	Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
cd06524	GH25_YegX-like	8.89e-19	86	285	1	190	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QCU01355.1	1.35e-162	1	517	1	506
CBL21600.1	5.79e-63	1	203	1	200
ASM68843.1	1.61e-55	64	326	73	333
SET59461.1	2.56e-44	61	399	31	312
AWY97591.1	2.91e-44	62	286	72	283

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2WAG_A	6.76e-13	86	288	17	207	TheStructure of a family 25 Glycosyl hydrolase from Bacillus anthracis. [Bacillus anthracis str. Ames]
3HMC_A	6.33e-12	88	266	8	171	Endolysinfrom Bacillus anthracis [Bacillus anthracis]
2G7C_A	8.60e-09	352	515	70	248	ChainA, Toxin A [Clostridioides difficile],2G7C_B Chain B, Toxin A [Clostridioides difficile]
4NC0_A	8.69e-09	352	515	72	250	ChainA, Cell wall-binding repeat protein [Clostridioides difficile NAP07]
4NBY_A	9.13e-09	352	515	77	255	ChainA, Cell wall-binding repeat protein [Clostridioides difficile NAP07],4NC1_A Chain A, Cell wall-binding repeat protein [Clostridioides difficile NAP07],4NC1_B Chain B, Cell wall-binding repeat protein [Clostridioides difficile NAP07]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P49331	4.01e-11	322	483	1204	1344	Glucosyltransferase-S OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gtfD PE=3 SV=3
P11001	1.63e-10	314	483	1146	1315	Glucosyltransferase-I OS=Streptococcus downei OX=1317 GN=gtfI PE=3 SV=1
P27470	1.76e-08	321	521	1392	1571	Glucosyltransferase-I OS=Streptococcus downei OX=1317 PE=3 SV=1
P76421	4.13e-08	87	266	69	245	Uncharacterized protein YegX OS=Escherichia coli (strain K12) OX=83333 GN=yegX PE=3 SV=2
Q8FFY2	5.54e-08	87	266	69	245	Uncharacterized protein YegX OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=yegX PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000283	0.999025	0.000160	0.000197	0.000161	0.000140

TMHMM Annotations download full data without filtering help

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