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CAZyme Information: MGYG000000003_01247

You are here: Home > Sequence: MGYG000000003_01247

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes shahii
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes shahii
CAZyme ID MGYG000000003_01247
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
667 MGYG000000003_2|CGC11 76070.21 7.629
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000003 3229518 Isolate United Kingdom Europe
Gene Location Start: 602592;  End: 604595  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL12 407 536 3.5e-57 0.9847328244274809

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 9.84e-169 33 386 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 1.19e-34 397 604 2 215
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBK62842.1 0.0 1 667 1 667
BCI64412.1 8.30e-238 30 666 27 672
BCA49284.1 3.05e-226 29 666 26 666
QQA07260.1 8.67e-226 29 666 26 666
AAO79762.1 8.67e-226 29 666 26 666

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JMD_A 1.76e-226 29 666 15 655
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 9.11e-219 32 627 18 614
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMH_A 7.36e-183 33 638 10 606
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A 7.36e-183 33 638 10 606
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
4FNV_A 6.89e-97 29 627 46 661
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C7EXL6 3.42e-221 14 666 11 666
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 6.78e-182 33 638 34 630
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
Q89YR9 3.77e-96 29 627 46 661
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000239 0.999072 0.000156 0.000175 0.000160 0.000147

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000003_01247.