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CAZyme Information: MGYG000000006_00068

You are here: Home > Sequence: MGYG000000006_00068

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus xylosus
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus xylosus
CAZyme ID MGYG000000006_00068
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
357 MGYG000000006_1|CGC2 40128.24 8.8853
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000006 2822527 Isolate United Kingdom Europe
Gene Location Start: 65715;  End: 66788  Strand: +

Full Sequence      Download help

MTKIAFTGGG  TVGHVSVNLS  LIPTALEEGY  EAFYIGSKNG  IEREMIESQL  PSIKYHSISS60
GKLRRYISWD  NIKDVFKVLK  GILDARRVLK  KEKPDLLFSK  GGFVSVPVVM  AAKSLKIPTI120
IHESDLTPGL  ANKISLKFAK  KIYTTFEDTL  QFLPKEKADF  VGATVREDLK  TGDKMRGYQL180
TEFNDNKKVL  LVMGGSLGSK  KLNSIIRENL  DALQTSYQII  HLTGKGLIDE  QYTNQKDYIQ240
FDFVKDDLTD  LLAITDTVIS  RAGSNAIYEF  LALRIPMLLI  PLGLDQSRGD  QIDNAKNFEA300
KGFGKTIPED  ALTEQKLIDQ  LNDIETNRDT  IINQMQTYKE  SFTRQDLFRK  IIKDALN357

Enzyme Prediction      help

No EC number prediction in MGYG000000006_00068.

CAZyme Signature Domains help

Created with Snap1735537189107124142160178196214232249267285303321339190339GT28
Family Start End Evalue family coverage
GT28 190 339 4.3e-35 0.9426751592356688

CDD Domains      download full data without filtering help

Created with Snap17355371891071241421601781962142322492672853033213391356murG1339PRK124463355MurG3353GT28_MurG3353murG
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.77e-141 1 356 1 352
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
PRK12446 PRK12446 3.07e-132 1 339 1 337
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
COG0707 MurG 1.19e-114 3 355 2 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
cd03785 GT28_MurG 1.26e-105 3 353 1 349
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
TIGR01133 murG 2.88e-86 3 353 2 346
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits      help

Created with Snap17355371891071241421601781962142322492672853033213391357QDW89198.1|GT281357CEF18809.1|GT281357AID42790.1|GT281357AID01370.1|GT281357ARD74533.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QDW89198.1 3.98e-256 1 357 1 357
CEF18809.1 3.98e-256 1 357 1 357
AID42790.1 3.98e-256 1 357 1 357
AID01370.1 1.62e-255 1 357 1 357
ARD74533.1 1.62e-255 1 357 1 357

PDB Hits      download full data without filtering help

Created with Snap173553718910712414216017819621423224926728530332133933563S2U_A33131F0K_A43177D1I_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 7.30e-28 3 356 4 352
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 6.41e-26 3 313 8 311
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 5.56e-24 4 317 12 326
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap17355371891071241421601781962142322492672853033213391357sp|Q49XM9|MURG_STAS11357sp|Q5HPC0|MURG_STAEQ1357sp|Q8CMM3|MURG_STAES1356sp|Q4L6C8|MURG_STAHJ1357sp|A5ISU9|MURG_STAA9
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q49XM9 3.69e-228 1 357 1 357
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=murG PE=3 SV=1
Q5HPC0 1.17e-210 1 357 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=murG PE=3 SV=1
Q8CMM3 1.17e-210 1 357 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=murG PE=3 SV=1
Q4L6C8 1.82e-202 1 356 1 355
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus haemolyticus (strain JCSC1435) OX=279808 GN=murG PE=3 SV=1
A5ISU9 2.19e-201 1 357 1 356
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Staphylococcus aureus (strain JH9) OX=359786 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000074 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000006_00068.