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CAZyme Information: MGYG000000012_00952
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacillus subtilis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus subtilis | |||||||||||
| CAZyme ID | MGYG000000012_00952 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Polyketide synthase PksN | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 941358; End: 957902 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1020 | EntF | 0.0 | 256 | 923 | 1 | 642 | Non-ribosomal peptide synthetase component F [Secondary metabolites biosynthesis, transport and catabolism]. |
| cd17646 | A_NRPS_AB3403-like | 0.0 | 496 | 995 | 1 | 488 | Peptide Synthetase. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| COG3321 | PksD | 0.0 | 4101 | 5193 | 3 | 1030 | Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]. |
| PRK10252 | entF | 0.0 | 34 | 1083 | 9 | 1047 | enterobactin non-ribosomal peptide synthetase EntF. |
| COG3321 | PksD | 0.0 | 1116 | 2148 | 3 | 1028 | Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAY90071.1 | 1.07e-265 | 216 | 1618 | 312 | 1714 |
| BAZ00088.1 | 3.60e-263 | 181 | 1618 | 277 | 1715 |
| BAZ75991.1 | 3.60e-263 | 181 | 1618 | 277 | 1715 |
| BAY30132.1 | 3.67e-263 | 181 | 1618 | 277 | 1717 |
| AFY93865.1 | 1.22e-216 | 384 | 1609 | 214 | 1446 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MHL_A | 2.37e-293 | 1114 | 1712 | 22 | 612 | Crystalstructure of ketosynthase twelve from bacillaene polyketide synthase in Bacillus amyloliquefaciens [Bacillus amyloliquefaciens],6MHL_B Crystal structure of ketosynthase twelve from bacillaene polyketide synthase in Bacillus amyloliquefaciens [Bacillus amyloliquefaciens] |
| 5ELP_A | 8.77e-270 | 1110 | 1712 | 20 | 617 | Ketosynthasefrom module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 [Bacillus amyloliquefaciens],5ELP_B Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 [Bacillus amyloliquefaciens],5ELP_C Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 [Bacillus amyloliquefaciens],5ELP_D Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 [Bacillus amyloliquefaciens] |
| 4NA1_A | 2.99e-252 | 2602 | 3207 | 24 | 632 | CrystalStructure of the second ketosynthase from the bacillaene polyketide synthase [Bacillus subtilis subsp. subtilis str. 168],4NA1_B Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase [Bacillus subtilis subsp. subtilis str. 168] |
| 4NA2_A | 6.54e-251 | 2602 | 3207 | 24 | 632 | CrystalStructure of the second ketosynthase from the bacillaene polyketide synthase bound to its natural intermediate [Bacillus subtilis subsp. subtilis str. 168],4NA2_B Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to its natural intermediate [Bacillus subtilis subsp. subtilis str. 168],4NA3_A Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to a hexanoyl substrate mimic [Bacillus subtilis subsp. subtilis str. 168],4NA3_B Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to a hexanoyl substrate mimic [Bacillus subtilis subsp. subtilis str. 168] |
| 4Z37_A | 2.79e-188 | 2594 | 3207 | 13 | 632 | Structureof the ketosynthase of module 2 of C0ZGQ5 (trans-AT PKS) from Brevibacillus brevis [Brevibacillus brevis NBRC 100599] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P40806 | 0.0 | 34 | 4541 | 695 | 4997 | Polyketide synthase PksJ OS=Bacillus subtilis (strain 168) OX=224308 GN=pksJ PE=1 SV=3 |
| Q2T4N2 | 0.0 | 1 | 3206 | 74 | 3458 | Polyketide synthase ThaH OS=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) OX=271848 GN=thaH PE=3 SV=1 |
| O31782 | 0.0 | 27 | 5514 | 1 | 5488 | Polyketide synthase PksN OS=Bacillus subtilis (strain 168) OX=224308 GN=pksN PE=1 SV=3 |
| Q2T4N1 | 0.0 | 1117 | 5470 | 14 | 4393 | Polyketide synthase ThaG OS=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) OX=271848 GN=thaG PE=2 SV=1 |
| P40872 | 0.0 | 1037 | 4724 | 319 | 4129 | Polyketide synthase PksM OS=Bacillus subtilis (strain 168) OX=224308 GN=pksM PE=1 SV=4 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000058 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |