CAZyme Information: MGYG000000021_00669

Basic Information

• Species: Limosilactobacillus vaginalis_A
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Limosilactobacillus; Limosilactobacillus vaginalis_A
• CAZyme ID: MGYG000000021_00669
• CAZy Family: GH25
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
702	MGYG000000021_7|CGC2	80567.17	5.8289

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000021	1945993	Isolate	United Kingdom	Europe

• Gene Location: Start: 53877; End: 55985 Strand: +

Full Sequence      

MTHKNHIYLASTLTLLSLSTSLYLNSKNVQADTEQVSTEQVNSNVNLNTDSASAQSQSAT
SATFATNSNDVASESAAEPTQSLSINSQNSAAPATAYTTVKAAAQTAYDGTPVINIGDAN
YPRVDAVDISGYQASMTPNNFVTLKNLGVKTAIVKVTEGTYYINRYAGQQINYAKNAGLN
VQVYHYAKFGSQNAAINEANYLANEMEALGLDKNTLIYADMEDTTTKYYGVANHLNAFWN
QLNTRGFTNHAVYASTSYDQTYNVSSTVGKNRTWVAQYLYSPSSANLRNQNYGAWQFNAH
GRIPGYNGDLDISIDYQGLVANSGEWSNNNGKWSYSINGNNVTGWQRINNNWYYFNQDGT
AQTGWYQSGAGNWYYFDYTNAWALTGWQYINNNWYYFDYNNAWADKGWQNINNNWYYFDL
TNAWALRGWQTINGNRYYFDPSNVWALKGFQYLDNAWYYFDDSNAWLSHGWRYNGGQWYY
LSPSTGQLESGLQTINGKVYYLQPNHNGYFGAMQTGWFNLNSHWYFFNNGGDAATGWFKS
PAGWWYYFDDNGQARTGWQTINGHQYYFDPTNASNYRGWYRHNNSWYYFDAANAWAVTGW
FKSPGGWWYYFDNDGRARTGWQTINNHKYYFDLTNASAYTNWQKLDGKWYYFDPNNAWTL
TGWQNINGHRYYFDNDGHAVTGYQYIDGKLYHFDQDNAWLLD

Enzyme Prediction     

No EC number prediction in MGYG000000021_00669.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH25	127	305	1.6e-33	0.9887005649717514

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06522	GH25_AtlA-like	1.00e-59	124	316	1	192	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml autolysins from Streptococcus mutans which have a C-terminal glycosyl hydrolase family 25 (GH25) catalytic domain as well as six tandem N-terminal repeats of the GBS (group B Streptococcus) Bsp-like peptidoglycan-binding domain. Other members of this family have one or more C-terminal peptidoglycan-binding domain(s) (SH3 or LysM) in addition to the GH25 domain.
NF033930	pneumo_PspA	1.39e-40	343	609	443	635	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033838	PspC_subgroup_1	9.99e-37	470	657	487	664	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033838	PspC_subgroup_1	3.34e-36	428	609	487	658	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033930	pneumo_PspA	1.41e-35	428	651	444	635	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QFS34607.1	7.30e-246	1	543	1	544
QFG72957.1	6.93e-139	1	370	1	336
ANK70427.1	2.33e-69	109	344	315	553
ANK62562.1	2.68e-69	109	344	325	563
QEA54166.1	9.04e-65	116	346	308	539

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4KRU_A	7.62e-14	123	330	19	222	X-raystructure of catalytic domain of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]
4KRT_A	3.61e-13	123	330	19	222	X-raystructure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101],4KRT_B X-ray structure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]
2WAG_A	4.97e-08	123	316	15	207	TheStructure of a family 25 Glycosyl hydrolase from Bacillus anthracis. [Bacillus anthracis str. Ames]
5A6S_A	7.72e-06	144	313	39	199	Crystalstructure of the CTP1L endolysin reveals how its activity is regulated by a secondary translation product [Clostridium phage phiCTP1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26836	2.47e-10	120	313	5	194	Probable autolytic lysozyme OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=lyc PE=3 SV=2
P34020	1.64e-08	127	321	4	186	Autolytic lysozyme OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) OX=272562 GN=lyc PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000938	0.996301	0.002096	0.000250	0.000186	0.000165

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000021_00669.