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CAZyme Information: MGYG000000027_01624

You are here: Home > Sequence: MGYG000000027_01624

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mitsuokella jalaludinii
Lineage Bacteria; Firmicutes_C; Negativicutes; Selenomonadales; Selenomonadaceae; Mitsuokella; Mitsuokella jalaludinii
CAZyme ID MGYG000000027_01624
CAZy Family GH36
CAZyme Description Alpha-galactosidase AgaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
746 MGYG000000027_12|CGC1 85614.83 5.3488
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000027 2393573 Isolate United Kingdom Europe
Gene Location Start: 13274;  End: 15514  Strand: -

Full Sequence      Download help

MGISFDATNQ  QFHLYNDRIS  YIMKVLRDGH  LGQLYFGARL  PEDRDYGHFV  HTDYYRPTSA60
YVFDNEYGFS  REHLRQEYPS  YGTTDFREGA  VEIAQPDGSH  ITDFCYVSHE  IVAGKPKLQG120
LPATYVEEDE  EADTLLVTLR  DEKTGVELVL  SYTIFRDFDA  IARNARFVNR  GNETVALTRA180
MSLAIDLPDA  DYDFVQFSGW  WGRERQKNAT  HLRPGIQSIG  SLRGQSGHVH  NPFFILKRPQ240
ADEQQGEAIG  FSLVYSGNFL  AQAEVDTFDV  TRVTMGIHPQ  EFCWQLAPED  SFQTPEAVMV300
WSDHGLNGMS  QNYHKLYRTR  LARGVWRDKV  RPILINNWEA  TYFDFDEEKL  VRIAKTAHDV360
GVELFVLDDG  WFSTRCGETS  GLGDWWPNTD  RLPNGITGLA  ERINGLGMKF  GLWVELEMVN420
KDSELYRAHP  DWILHTEGRH  ASHGRKQYVL  DFSRPEVVDY  IHDSIYKVLS  TAKVDYIKWD480
MNRSITECGS  SGWGPEHQGE  IFHRYILGVY  SLYERLTSEF  PNILFESCAS  GGGRFDPGMF540
YYAPQCWTSD  DSDGGERLRI  QYGTSYAYPV  SFMGSHVSIA  PNHQIFRNTS  LKLRGDVAYF600
GTFGYELDLG  KLSAKELDEV  REQIRFMKKY  RKLIQQGTFY  RLKDPFTGNA  AAWMVVSDDR660
RQAIVGYYKM  LAHPCTPYTW  MKLAGLDEAA  DYTVRIDDRE  EMGQFTGAEL  MRAGLDTTDF720
SAGEQSREEG  RHCTDFWSRL  FVVEAK746

Enzyme Prediction      help

EC 3.2.1.22

CAZyme Signature Domains help

Created with Snap377411114918622326129833537341044748452255959663467170812716GH36
Family Start End Evalue family coverage
GH36 12 716 7.6e-282 0.9956395348837209

CDD Domains      download full data without filtering help

Created with Snap37741111491862232612983353734104474845225595966346717089730GalA291637Melibiase331629GH3629287Glyco_hydro_36N651742Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 0.0 9 730 1 683
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 0.0 291 637 1 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 3.58e-140 331 629 2 299
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 5.64e-119 29 287 1 256
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 3.80e-20 651 742 2 77
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap37741111491862232612983353734104474845225595966346717081745QDW75218.1|GH361746QZN92981.1|GH361746BAG28113.1|GH361746ADJ41691.1|GH361746AGL89862.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
QDW75218.1 0.0 1 745 1 741
QZN92981.1 0.0 1 746 1 742
BAG28113.1 0.0 1 746 1 740
ADJ41691.1 0.0 1 746 1 740
AGL89862.1 0.0 1 746 1 740

PDB Hits      download full data without filtering help

Created with Snap377411114918622326129833537341044748452255959663467170817154FNQ_A17154FNR_A17154FNU_A17154FNT_A17154FNP_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNQ_A 1.98e-277 1 715 1 708
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNR_A 1.85e-275 1 715 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNU_A 1.72e-273 1 715 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus]
4FNT_A 2.44e-273 1 715 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus]
4FNP_A 3.46e-273 1 715 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNS_A Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap37741111491862232612983353734104474845225595966346717081715sp|Q9ALJ4|AGAA_GEOSE3722sp|G1UB44|MELA_LACAC3715sp|P43467|AGAL1_PEDPE1721sp|G4T4R7|AGASK_RUMGN74718sp|Q5AU92|AGALC_EMENI
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9ALJ4 1.01e-274 1 715 1 708
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
G1UB44 1.04e-204 3 722 6 723
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
P43467 3.13e-201 3 715 4 711
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
G4T4R7 1.25e-188 1 721 1 707
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
Q5AU92 3.73e-178 74 718 95 735
Alpha-galactosidase C OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=aglC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000080 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000027_01624.