CAZyme Information: MGYG000000032_04093

Basic Information

• Species: Hungatella effluvii
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella effluvii
• CAZyme ID: MGYG000000032_04093
• CAZy Family: GH136
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1928	MGYG000000032_12|CGC6	208708.54	4.2165

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000032	6969476	Isolate	United Kingdom	Europe

• Gene Location: Start: 190126; End: 195912 Strand: -

Full Sequence      

MYSLSRWKTRMTACIVSGAVAFSTLFPVPAAAAGKMAAYDGSEVVDLAGNREMKAYGERL
VTGGRALVSRDYGEEAGTGITYYLDSEAGNDENEGTSEDKPWKSLEMVNNRTFQPGDRIL
LKAGSVWEEETLSPKGSGEEGNPIVIGAYGDGEKPKLTGNAAVPEVVSLYNQQYWELSDL
EITNTAAGFTGAMNDQNGNKLKDVRGIRIAGQDGGDLYNYYLHDLYVHDVTGVCAWISGD
NNGKPGILGKQGWDKSKRTGGILFEVLEPATDQPTVFHDITVERNVVNNNSFGGIIVKQW
KGADTGGEHWASREEGKGNAANNYYCENWKPHTDVTIRDNYLSQENSDYACNTIYLTSVQ
GAVVEGNISKEAGTCGIEMYYADGVTVQRNEVYKTRVKAGGADSNAIDPDKASTNILIQY
NYIHDTGDGILLCGFIFGTSVVRYNVIKDAQKRYINPHGDKGVNYVYNNILYNTIEKSNL
PFIESSGGNGVYLNKSGNMHYINNNIFYNTAKTTTSVGIGEGPSTSYDSNCYYGKGVQAP
EQETRAVCGDPMFEGGLTGDEDDGAAELLKLRLKPESPLLNAGTQIEDDPLLSISANPGS
DFAGAPLFNGEPDMGIFEYQGEAGSGILNGYVEDPFGNIMKGAAVKLKDTDYAAVTDEQG
FFAIAGVKPGSYTAVISKEIYLDGETPDITVEEKAVTRVQLRLGESLSDVGSVKGCVSNS
SGPLQGVTVTASLGDLVFTAKTGNDGCYEMTDVKIGTGYVVTASKEGYTTAATEEVRVMP
AAAAEVNLILSKEIGKTTYLIADLFDQYDAGAFTNSSSGNNIWKVSDISAADASKASLQI
KAEGNGNKYLEMAKTGSYSLYAYTKKEYDLSGIITVEARVKRTAESASANQFGMYSFNKA
DFKTGDPTGSSNAIGTFALTKGNIVTHNKKGSSNTVNVQGYTKNEWDIIRNVINLDTNTF
DFYVNDMNVPKLADQPLRTQGKNIDRFEFFSSGSNVGDLLIDYFKVCTGPAMDYDDAGIS
GIRVDGNEAEWKGGNIYELEISSGSSEVKVQPAASSIFARKIMVGDQDATKDAVTVPVSG
SGDSLRITVLAEDGETEESYQLNLVKEDAAGLAYLTSLAMEGVTLTPEFDFNTMEYEGEV
PSDVSRVTLQYETVQASNEVTIKVNNQYVTDPVIPLKPGVNVIEIGVASADGTSFADYTV
IVTRDCVIDGIRIDTLPVKTVYERGEEPDFEGLTVGAYCEGERVRVLDAAEFAVSMPDTS
ETGTVPVTVTYVTEDGMTLEAVFDITVYDRDTMEPQSIKVVKPPEQTVYGTGEAFQPDGM
EVRLLMKATASNAAPAEVRILDDGEYDAIGDFTEPGDTKVAIRYTWTDSEGEERYLEDSV
AVTVYDEELDYYETGITVTKQPKKTVYETGSVFDPEGMEVKRTMKASGSNAVYYKETITD
YDYDADELTKTGTRKISVSHEGTDKDGEDRTFTTGVTVTVTNREDILKNAVLEQSVAGAR
EILNKENVAYVTEEEKAAAADAAKEVFLDVMGAEHTVLTKEMADRMVELEALLKNAYPGI
TIRVEGDSKLTEGAEVAGALLNAPLGQGNLTIVSRITGTKLPEDIPETKAAAAMEIKLLV
NGEELQPDIPLYMTLKIPEGINKADLIIYHVLDDGSIEVIDPEISGGFLRFFVRSFSTFV
IANPKEADLTGIEITAQPKKTEYRIHEAFDASGLVVTAVYEDGTKAAVTEYGLAGFDAAT
AGIKTITVSYKGKTAKFTVTVKAEDDGSGDDDNGDNDDGGGNNGSGSHGSSGSPVVRSVL
PDTVKGSWKQNENGWWFETLDGGFVKSDWARINEKWYYFGDQGYMAVGWVLDQNHWYYLG
ADGAMAADAWILDRGAWYFLQSGGAMAADQWVQWNGNWYYLNSDGSMAKDTVVTVGYRIG
EDGVWRPD

Enzyme Prediction     

No EC number prediction in MGYG000000032_04093.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH136	79	618	4.9e-118	0.9959266802443992

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033838	PspC_subgroup_1	1.74e-24	1801	1908	481	585	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033840	PspC_relate_1	7.02e-23	1797	1925	504	646	PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
NF033930	pneumo_PspA	4.04e-22	1801	1908	438	542	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033930	pneumo_PspA	1.28e-21	1808	1908	485	582	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
COG5263	COG5263	3.36e-20	1803	1925	191	312	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASA23882.1	2.63e-169	79	1284	39	1233
CQR57267.1	3.11e-168	78	1202	38	1145
QDH21977.1	7.88e-162	82	1204	53	1155
BBC61707.1	8.61e-155	61	618	60	598
BAL62976.1	8.61e-155	61	618	60	598

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7V6M_A	5.73e-37	74	618	3	576	ChainA, Fibronectin type III domain-containing protein [Tyzzerella nexilis]
6KQS_A	7.12e-27	79	500	244	663	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative [Eubacterium ramulus ATCC 29099]
6KQT_A	9.42e-27	79	500	244	663	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein [Eubacterium ramulus ATCC 29099]
5GQC_A	5.18e-22	69	618	3	596	Crystalstructure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_C Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_D Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_E Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_F Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_G Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_H Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQF_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQF_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum]
7V6I_A	5.73e-19	74	618	8	608	ChainA, Lacto-N-biosidase [Bifidobacterium saguini DSM 23967]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A0A401ETL2	2.75e-08	1670	1763	1362	1453	Exo-beta-1,6-galactobiohydrolase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=bl1,6Gal PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000433	0.998698	0.000224	0.000235	0.000208	0.000169

TMHMM  Annotations     

start	end
12	34