CAZyme Information: MGYG000000032_04741

Basic Information

• Species: Hungatella effluvii
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella effluvii
• CAZyme ID: MGYG000000032_04741
• CAZy Family: GH136
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1571		172231.5	4.3001

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000032	6969476	Isolate	United Kingdom	Europe

• Gene Location: Start: 114279; End: 118994 Strand: +

Full Sequence      

MQKTSKRFKRKAAGMMAAVMMMSALPVNMVGFADTSVNSRDSYDTNDRTATDSNASLSTA
SNALKMQTEGTTYYVDARDGNDTADGKTEDTAWKSFDRVNSKTFLPGDKILLKSDCIWNQ
PLNPKGSGQEGAPITIDRYGEGSRPVINGNGTSGPSITGAVTIYNEEYWEIYNLEVTNLE
STDEMGEAMDSGTSERAGILIYSSNQKEIYKHIVVKNCYVHDVNSNFKGGKTSGGIIVMG
HYLDKDGNRVTIDDNGNLTPKAMGRAAFEDVLIEGNYVKNVAIEGIRNKCNTDIGSSGWG
KNEFLKNYSNVTIRNNYLEDVVGDGIVLTETKGGLVEGNMVNSSCGLDRGTVNYAQCWTM
FADDVIVQYNEAYGNKYGYDDGEAFDSDMMNVDNIFQYNLSHDCGGGAMLFMSSQKNTIF
RYNVSINDGTGTYPNGSRMQQQTFHYDNTSSAGPNVGKIYNNTIVVFGEGKQTSLFGGKS
KRTCFVDFKNNIVLAKDGAVIDFAVLEQGSAIHEDSVIENNCFYPDTIANTNAGSVLDKD
SLTAKGNIFADPMLKDYKAGETYSAYQYPLEDLEDLIDSDFTKERIQGLAEPYQLTDGSP
CIQAGQRIEGMPTEDIMGNTIAGRVDIGALEYSSQDEEAEEVEEVNLVTTLGVVPELPGT
LKVVLDGTAYQYPVEWEELTKEDCMEAGVIELPGVLPGLSNQVTATIVVADAPESYESVD
VTTFAGIYPELPDKVNAVFAGGLTMELEVVWDKLTLEQYSREGEFTVEGRVSGLKEKCAA
TVRVIGDLGDGKTVKETGAVKDAFTQEKDGDAAYGKLTPNVIKVKTASSDPAYTRRGLLG
FDLTNESEMLKSATNITIKLQMTRPVSDSDYKNINNHFYLKVYEIGDEWQEETVTWNTTP
AFSADNLVIKDKKIVYKDIRDNHENIVELDVTDWVKKAYAENGQTKFSFLMLTDYFGEYA
NGDNGGIDFASREASGMMEPTIVLSNVYEMKVDAVSVSTSAGKKPVLPETVTVTYSNEET
KSVSVEWNSINPANYQTEGTFVVYGKAEGINLPITCTVNVMEALHKVVAVKDIPGIIQLV
GTPWEELGLPEMATVLLDNGQEAEVGIQYWFPDNAYDPEKEFSYTCIGYLDLANHDSIEN
PEQKFATVSVSIIEPEDKNALLVLYTEAAGLINSGEVGQLTESAKNRFMKAFNKAAEVLV
NTKATELEVHTAYTELMEAIWNMDSEENQKADTDALRDLVLIAESKKKKDYTEETYDAMR
EALSEAKAVLRDKTLTKADQPIVDMAYENLKEAVDALVLSGKTDPVTKVMTGIKITALPS
KTEYKVGERFSSSGLSVAAVYSDGSTKTVSGYEIGDVNTGTAGTKDVVVTYRIAVNDAIK
VFTDTFQITVVKRSSSGGSSGSSSGGGSSSVRVNRTAVNVSGEWQAAENNTWRFQKSDGS
YAKNEWARINDKWYHFDGSGYMQTGWILDGDKWYKLGSDGSMHTGWVKEEADGQWYYLNE
SGAMMTGWTMVNGTWYYLNPVTQGNTGWQNTEDGKWNRGSAESGSRSMGALYTGTTTPDG
YQVDENGAWIQ

Enzyme Prediction     

No EC number prediction in MGYG000000032_04741.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH136	70	631	3.2e-122	0.9959266802443992

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033930	pneumo_PspA	6.21e-31	1429	1570	489	660	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033840	PspC_relate_1	1.22e-28	1428	1571	515	648	PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
COG5263	COG5263	2.03e-28	1413	1570	185	313	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].
NF033930	pneumo_PspA	3.01e-28	1428	1568	448	580	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033838	PspC_subgroup_1	3.33e-27	1428	1567	491	622	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SET83278.1	0.0	1	1571	1	1571
ADL05164.1	0.0	1	1571	1	1579
QRV20653.1	0.0	1	1571	1	1579
QOL17747.1	8.28e-151	70	1180	51	1185
AFO44703.1	1.59e-150	70	1180	51	1185

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7V6M_A	1.98e-32	65	634	3	579	ChainA, Fibronectin type III domain-containing protein [Tyzzerella nexilis]
6KQT_A	5.38e-23	70	411	244	599	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein [Eubacterium ramulus ATCC 29099]
6KQS_A	2.16e-22	70	411	244	599	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative [Eubacterium ramulus ATCC 29099]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000348	0.998901	0.000194	0.000212	0.000169	0.000145

TMHMM  Annotations     

start	end
13	32