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CAZyme Information: MGYG000000033_00196

You are here: Home > Sequence: MGYG000000033_00196

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-41 sp900066215
Lineage Bacteria; Firmicutes_A; Clostridia; Monoglobales_A; UBA1381; CAG-41; CAG-41 sp900066215
CAZyme ID MGYG000000033_00196
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1053 MGYG000000033_1|CGC3 119867.75 8.8392
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000033 3010191 Isolate United Kingdom Europe
Gene Location Start: 222869;  End: 226030  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000033_00196.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 633 860 8.3e-52 0.9147982062780269

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 3.30e-21 876 1048 7 198
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG5542 COG5542 7.13e-21 62 388 65 385
Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].
COG1928 PMT1 5.84e-16 860 1053 489 696
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 8.74e-15 630 804 16 204
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG1928 PMT1 1.12e-13 660 890 90 292
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCN30459.1 1.57e-302 28 1053 32 1059
QNM01664.1 1.32e-250 28 1053 24 1086
BBF42044.1 4.07e-240 135 1053 2 921
AIQ66842.1 3.43e-215 38 1051 12 1030
CQR52353.1 8.18e-213 14 1051 225 1274

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8NRZ6 1.03e-24 608 1050 53 519
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1
P9WN04 1.83e-22 615 1050 69 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 1.83e-22 615 1050 69 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
O67270 1.11e-06 628 806 38 196
Uncharacterized protein aq_1220 OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_1220 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999965 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
4 23
36 58
92 111
118 140
167 189
196 218
238 260
267 284
294 316
323 340
345 362
367 386
396 418
481 500
679 701
708 725
730 749
761 780
784 801
838 860
930 947
954 971
976 998
1007 1029