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CAZyme Information: MGYG000000034_00413

You are here: Home > Sequence: MGYG000000034_00413

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Massilimaliae timonensis
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Massilimaliae; Massilimaliae timonensis
CAZyme ID MGYG000000034_00413
CAZy Family GH42
CAZyme Description Beta-galactosidase BglY
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
674 MGYG000000034_1|CGC4 76776.61 5.1298
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000034 2753532 Isolate United Kingdom Europe
Gene Location Start: 411176;  End: 413200  Strand: -

Full Sequence      Download help

MVLEKFPHLL  HGGDYNPDQW  LEYPDILEKD  IELMKKAKIN  CVSLAIFAWA  TLEPEEGVYH60
LEWLKKIVDR  LYQEGIYTVL  ATPSGAMPRW  LTEKYPEVMM  VSAERVRNLP  GGRHNFCPTS120
PVMRQKIQAL  DALIAQELGN  HPGVILWHIS  NELGGNGTHG  ECHCPLCQQA  FREWLKAKYK180
TLDALNHAWW  ADFWSHTYTS  WEQIESPAPH  GEMGIHGLNL  DWKRFCNEQM  MDFTKEEIKT240
VKQYSNDLPA  TVNMMTFFKD  LDYFKFAGLV  DVISWDSYPN  WHAEETELKA  ATETAFMHDL300
MRSLKKAPFL  LMESTPSITN  WKPVNTQKRP  GMHKLASLQA  VAHGSNSVQY  FQIRKGRGSF360
EKFHGAVISH  QNTENMRSFR  EVTELGACLE  QISDRVYPTL  NKADVAIVFD  WENWWAVEDA420
KGPIVPLDYA  GTVMMHYRPF  WKMGVTTDII  DMDCDLSEYK  IVVAPMTYMM  KAGFAEQVRR480
FVEKGGVFVT  TYWSGMVDET  DLCFMGGFPG  LITDVMGLEE  EEIDAIGPHR  KNTVSYGGNS540
YSVGALRDVI  HTTTAKTLAE  YEADYYKGSP  AVTVNAFGKG  KAYYICSENE  DAFFDAFYRD600
LVKEEAVAAN  WPDELPEGVT  VSKRVGKESL  LFIQNFNEAE  ISMDLAKEYR  TVAGETVSGT660
LFLKPFDCVI  LIEK674

Enzyme Prediction      help

EC 3.2.1.23

CAZyme Signature Domains help

Created with Snap336710113416820223526930333737040443847150553957260664014390GH42
Family Start End Evalue family coverage
GH42 14 390 4.2e-150 0.9946091644204852

CDD Domains      download full data without filtering help

Created with Snap33671011341682022352693033373704044384715055395726066401671GanA14392Glyco_hydro_42403608Glyco_hydro_42M405550A4_beta-galactosidase_middle_domain618671Glyco_hydro_42C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1874 GanA 0.0 1 671 8 670
Beta-galactosidase GanA [Carbohydrate transport and metabolism].
pfam02449 Glyco_hydro_42 0.0 14 392 1 376
Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.
pfam08532 Glyco_hydro_42M 3.71e-90 403 608 1 207
Beta-galactosidase trimerisation domain. This is non catalytic domain B of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. This domain is related to glutamine amidotransferase enzymes, but the catalytic residues are replaced by non functional amino acids. This domain is involved in trimerisation.
cd03143 A4_beta-galactosidase_middle_domain 2.19e-38 405 550 1 145
A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to beta-galactosidase from Thermus thermophilus. Beta-Galactosidase hydrolyzes the beta-1,4-D-galactosidic linkage of lactose, as well as those of related chromogens, o-nitrophenyl-beta-D-galactopyranoside (ONP-Gal) and 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal). This A4 beta-galactosidase middle domain lacks the catalytic triad of typical GATase1 domains. The reactive Cys residue found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow in typical GATase1 domains is not conserved in this group.
pfam08533 Glyco_hydro_42C 1.18e-04 618 671 1 56
Beta-galactosidase C-terminal domain. This domain is found at the C-terminus of beta-galactosidase enzymes that belong to the glycosyl hydrolase 42 family.

CAZyme Hits      help

Created with Snap33671011341682022352693033373704044384715055395726066403671QAA31549.1|GH425674QRT49317.1|GH425674QQR00168.1|GH425674ANU45071.1|GH422674CEP78374.1|GH42
Hit ID E-Value Query Start Query End Hit Start Hit End
QAA31549.1 0.0 3 671 5 676
QRT49317.1 1.44e-271 5 674 7 677
QQR00168.1 1.66e-270 5 674 7 677
ANU45071.1 1.66e-270 5 674 7 677
CEP78374.1 2.72e-270 2 674 8 686

PDB Hits      download full data without filtering help

Created with Snap336710113416820223526930333737040443847150553957260664016745E9A_A96744OIF_A96744OJY_A96745DFA_A16743TTS_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5E9A_A 1.82e-252 1 674 31 709
Crystalstructure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_B Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_C Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_D Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_E Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_F Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3]
4OIF_A 3.50e-228 9 674 15 684
3Dstructure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_B 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_C 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus]
4OJY_A 3.62e-228 9 674 16 685
3Dstructure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],4OJY_B 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],4OJY_C 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus]
5DFA_A 2.83e-227 9 674 15 684
3Dstructure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],5DFA_B 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],5DFA_C 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus]
3TTS_A 6.67e-202 1 674 1 674
ChainA, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_B Chain B, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_C Chain C, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_D Chain D, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_E Chain E, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_F Chain F, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_A Chain A, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_B Chain B, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_C Chain C, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_D Chain D, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_E Chain E, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_F Chain F, Beta-galactosidase [Niallia circulans subsp. alkalophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap33671011341682022352693033373704044384715055395726066406674sp|C8WV58|BGAL_ALIAD2674sp|Q0TUR6|BGAL_CLOP19673sp|O07012|BGAL2_BACSU9673sp|Q65CX4|BGAL2_BACLD1671sp|Q9KI47|BGAL_PLASS
Hit ID E-Value Query Start Query End Hit Start Hit End Description
C8WV58 1.52e-257 6 674 8 683
Beta-galactosidase BglY OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / BCRC 14685 / JCM 5260 / KCTC 1825 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-IA) OX=521098 GN=bglY PE=1 SV=1
Q0TUR6 7.24e-241 2 674 7 689
Beta-galactosidase Pbg OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=pbg PE=3 SV=1
O07012 7.41e-216 9 673 1 670
Beta-galactosidase GanA OS=Bacillus subtilis (strain 168) OX=224308 GN=ganA PE=1 SV=2
Q65CX4 4.02e-213 9 673 1 670
Beta-galactosidase GalA OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) OX=279010 GN=lacA PE=1 SV=2
Q9KI47 1.24e-191 1 671 1 674
Beta-galactosidase BgaA OS=Planococcus sp. (strain 'SOS Orange') OX=128803 GN=bgaA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000041 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000034_00413.