CAZyme Information: MGYG000000035_02638

Basic Information

• Species: Blautia_A hydrogenotrophica
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A hydrogenotrophica
• CAZyme ID: MGYG000000035_02638
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
814	MGYG000000035_6|CGC1	94612.95	6.3993

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000035	3529525	Isolate	United Kingdom	Europe

• Gene Location: Start: 44021; End: 46465 Strand: +

Full Sequence      

MNQQLLEVKRERFHLLNPNVYILQGTFPKEYELAAYLDSVRIEARMEDWETTSALERFKE
WELLNGRKVTVYVDLPQNLREFKKLKLMAVLEGEKLPWFTVSVKELLERQGKPQYYIEEE
RVNVREKTCQIRGWAVAQQRVAVKVFDEEKKPVACSIQMTNRVDVTEMYKECQVEEKCGF
FIQLEQVKSRKLYLVFWTPQGKAVHTVSLQPVVILKNKIEKYRKKGMSYLKTHGVRALAV
KTVHKLTTVKERPVDYQKWLPKHLPGNAELEKQRKTRFELQPKISIVVPLYKTDKEYLRQ
LIESVQAQTYGNWELCLSDGSGSQSPLKETLEEYRRQDERIRVVSSSEPLQISQNTNAAI
AAATGDFIAFADHDDVLTPHALFECVKAYNENPKLEIFYSDEDKMTMDGNKFFQPHFKPD
FNLDLLCSVNYICHLFVAKRTLIETVGVLRPEFDGAQDYDFIFRCVEATKEICHVPKILY
HWRSHEQSTSENPESKRYAFEAGQRAVQAHYDRIGVKAQVLQGEYLGLYRTRFLRDHDPL
ISIIIPNKDHIDDLRRCMESIEEKSTYRNYEYIIVENNSTEAETFAYYKKLEAENPKVNV
IYWDGPFNYSAINNFGAEHAKGEYLLLLNNDTEIINPDCLEELLGYCMRPDVGIVGARLY
YEDDTVQHAGVVLGFGGIAGHCFVQQPRSSTGYCHRIICAQDYSAVTAACMIVKKEIFDA
VGGLSEDLQVAFNDIDFCIKVRDYGKLVVYNPYAELYHYESKSRGLEDTPEKIARFNKEI
ATLEQHWPDIFRKPDPYYNPNLTLDSQDFSLKRL

Enzyme Prediction     

No EC number prediction in MGYG000000035_02638.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	285	398	2.4e-24	0.6823529411764706
GT2	542	672	2.2e-21	0.7529411764705882

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04184	GT2_RfbC_Mx_like	2.84e-97	282	483	1	201	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
cd04186	GT_2_like_c	1.60e-45	543	760	1	166	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	3.58e-29	539	765	3	226	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
cd06433	GT_2_WfgS_like	5.21e-22	285	490	1	201	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
pfam00535	Glycos_transf_2	2.97e-21	542	667	1	124	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBL24563.1	0.0	1	814	1	814
CBL21587.1	0.0	1	814	1	815
QOV20089.1	0.0	1	814	1	814
QCU01344.1	0.0	1	814	1	815
QJU15224.1	0.0	1	814	1	816

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HEA_A	7.04e-09	284	392	7	112	CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P55465	1.79e-153	277	811	361	897	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1
Q50864	1.33e-110	255	813	292	842	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1
P71057	1.65e-13	282	503	4	230	Putative glycosyltransferase EpsH OS=Bacillus subtilis (strain 168) OX=224308 GN=epsH PE=2 SV=1
Q58457	2.89e-13	281	466	7	195	Uncharacterized glycosyltransferase MJ1057 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ1057 PE=3 SV=2
P71054	3.16e-09	282	382	5	104	Putative glycosyltransferase EpsE OS=Bacillus subtilis (strain 168) OX=224308 GN=epsE PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000039	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000035_02638.