logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000037_01379

You are here: Home > Sequence: MGYG000000037_01379

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Turicibacter sp001543345
Lineage Bacteria; Firmicutes; Bacilli; Haloplasmatales_A; Turicibacteraceae; Turicibacter; Turicibacter sp001543345
CAZyme ID MGYG000000037_01379
CAZy Family GH36
CAZyme Description Alpha-galactosidase AgaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
743 MGYG000000037_17|CGC1 85731.39 5.1061
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000037 2730783 Isolate United Kingdom Europe
Gene Location Start: 23063;  End: 25294  Strand: -

Full Sequence      Download help

MPILFNEQTK  EFHLYNDEVS  YIMNILPNHQ  LGQLYYGKKI  RHNDSFAHLL  EERPRPLSAC60
AFEGNMSFSM  EHIKQEYPCY  GTGDFKYPAY  EILQQNGSDI  TNFEYVSHCI  YNGKPRLSDK120
LPATYVEVDE  EATTVEVTLK  DELIQTKLVL  TYTIYETRPV  ITRNARFKHL  GEEQITLTSA180
MSASVDLPDY  DYEMIELTGA  WSRERYVKNR  KLEHGIQAVY  SMRGASSSNY  NPFLALKRPH240
TTEFDGEVYG  FSLVYSGNFL  AQAEVHTYGT  TRVMMGLHPN  RFNWVLSQGE  EFQTPEVVMV300
YSENGLNGMS  QTYHELYRTR  LCRGYWRDRV  RPILVNNWEA  TYFDFNEDKI  VSIAKDAKDL360
GIELFVLDDG  WFGNREDDTV  GLGDWYVKNF  EKLPNGITGL  ANRVTELGIK  FGLWFEPEMV420
NKDSDLYRAH  PDWILTTPNR  RACHGRNQYV  LDFSRQEVVD  YIYEAMAKVL  GEAPISYVKW480
DMNRNITECF  SAVANAADQG  KVFHKYILGV  YDLYDRLTTK  FPEILFESCA  SGGSRFDPGM540
LYYAPQTWTS  DDTDAIERLK  IQYGTSMVYP  ISSMGSHVSA  IPNHQLYRHA  PLSTRANVAY600
FGTFGYELDL  NKLTDVEKEE  VKEQIKFFKE  YRETIFNGTF  YRLVSPFEGN  ETCWMMVSPD660
QKTALVGYYR  PLNEVNVGFR  RVKLQGLNPD  FKYHVSINET  THYGDELMNA  GLITSDGSCG720
ENKNPYDGTN  GDYQSRIYVL  TAE743

Enzyme Prediction      help

EC 3.2.1.22

CAZyme Signature Domains help

Created with Snap377411114818522226029733437140844548252055759463166870512713GH36
Family Start End Evalue family coverage
GH36 12 713 3.3e-288 0.9956395348837209

CDD Domains      download full data without filtering help

Created with Snap377411114818522226029733437140844548252055759463166870511712GalA292638Melibiase331630GH3630286Glyco_hydro_36N651740Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 0.0 11 712 3 665
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 0.0 292 638 2 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 2.46e-148 331 630 2 299
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 1.45e-116 30 286 2 255
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 4.68e-29 651 740 1 78
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap37741111481852222602973343714084454825205575946316687051743AMC08872.1|GH361743QJS19094.1|GH361743QQV07607.1|GH361743QQY28594.1|GH361743QMW74123.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
AMC08872.1 0.0 1 743 1 743
QJS19094.1 0.0 1 743 1 743
QQV07607.1 0.0 1 743 1 741
QQY28594.1 0.0 1 743 1 741
QMW74123.1 0.0 1 743 1 741

PDB Hits      download full data without filtering help

Created with Snap377411114818522226029733437140844548252055759463166870517124FNR_A17424FNQ_A17124FNU_A17124FNT_A17124FNP_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNR_A 1.08e-288 1 712 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNQ_A 1.53e-288 1 742 1 726
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNU_A 1.01e-286 1 712 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus]
4FNT_A 1.43e-286 1 712 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus]
4FNP_A 2.03e-286 1 712 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNS_A Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap37741111481852222602973343714084454825205575946316687051712sp|Q9ALJ4|AGAA_GEOSE3742sp|G1UB44|MELA_LACAC3712sp|P43467|AGAL1_PEDPE1712sp|G4T4R7|AGASK_RUMGN71712sp|Q0CEF5|AGALG_ASPTN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9ALJ4 5.92e-288 1 712 1 708
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
G1UB44 1.45e-217 3 742 6 730
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
P43467 1.66e-208 3 712 4 711
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
G4T4R7 3.74e-199 1 712 1 701
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
Q0CEF5 6.19e-175 71 712 67 707
Probable alpha-galactosidase G OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=aglG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000050 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000037_01379.