CAZyme Information: MGYG000000039_01734

Basic Information

• Species: Faecalibacterium prausnitzii_H
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Faecalibacterium; Faecalibacterium prausnitzii_H
• CAZyme ID: MGYG000000039_01734
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
795	MGYG000000039_9|CGC1	88386.37	6.6029

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000039	2848022	Isolate	United Kingdom	Europe

• Gene Location: Start: 54764; End: 57151 Strand: -

Full Sequence      

MEHYDWNDGWLFTPTFDPAIVRPECPELALEPVRIPHTVKTLPYNYCNENDYQRLCGYRR
EFFAPKEWQGRTVLLTFDAVAHDATVFCNGRRVFHHGCGYTAFTVDLTEALRLGEKNVLA
VRCDSREDLNIPPFGGQIDYLTYGGIYRAVSLDVKEPAYLRDIFMEAQAEGDFRIYTSTV
GETVGCTLQAEIRSPAGSRALYDGELSLPIVGTLNGVHPWSIDHPFLYTLTVRLIRPGTG
GLPDRVLDEKSTRFGFRTIQFVAGGLYLNGQRVEVRGLNRHQSYPYQGYAMPDSIQQLDA
HILKKQLGCNAVRTSHYPQSPAFLDACDELGLLVFLEMPGWQYIGDESWKAQALQNCREM
VCQCRNHPSVFLWGVRVNASADDEAFYKRTNEAVHRLDPTRPTAGVHIRRKDQLLEDVYA
YNDHSYAGRGPGCENRANVTPDIRKGYLISEFGGQQFPAKAFDDEPHRLVQALHHAAVLN
DAIAQPGVAGALGWCMADYNTHKEFGSGDRICYHGVLDMFRNPKLSAAVYASQKTPRSPS
DIVLEVSSSMALGDHPGGFAGACWVFTNAESVRLYRGNDFIAEFTPDRRGRFAALPHPPI
EVQDFVGSLLEKYEGLDPVAAPQVAAILNEMRRDALALSPLSRARLLSLRLGWNDLLRMY
YKYIGVLGSPSSVYRFEAVWHGRAVRTVVKEPVQSVRLECTVLNPLLTDGPTWDCAAVSL
RAIDQNGNLLPYCGEAVQLSVEGPVKILGPSVVPLRGGMAGTYLATTGEAGRAVLHCKME
GALDTEAALTVRKRG

Enzyme Prediction     

EC	3.2.1.23

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	7	532	5e-102	0.6103723404255319

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	5.63e-62	41	521	46	551	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	4.85e-52	58	408	69	450	beta-D-glucuronidase; Provisional
PRK10340	ebgA	2.17e-39	58	401	113	470	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	2.54e-34	58	402	124	484	beta-galactosidase.
pfam02836	Glyco_hydro_2_C	4.26e-26	264	536	6	299	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ATL89948.1	0.0	1	794	1	794
QIA41867.1	0.0	1	794	1	794
ATO99743.1	0.0	1	794	1	794
CBL01748.1	0.0	1	794	1	794
AXB27888.1	0.0	1	794	1	794

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5EUV_A	1.16e-153	7	791	8	730	ChainA, Beta-D-galactosidase [Paracoccus sp. 32d],5EUV_B Chain B, Beta-D-galactosidase [Paracoccus sp. 32d],5LDR_B Chain B, Beta-D-galactosidase [Paracoccus sp. 32d]
5LDR_A	1.20e-153	7	791	9	731	ChainA, Beta-D-galactosidase [Paracoccus sp. 32d]
6ED1_A	5.44e-44	7	524	30	589	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei]
6MVG_A	1.90e-42	2	531	26	573	Crystalstructure of FMN-binding beta-glucuronidase from Ruminococcus gnavus [[Ruminococcus] gnavus],6MVG_B Crystal structure of FMN-binding beta-glucuronidase from Ruminococcus gnavus [[Ruminococcus] gnavus],6MVG_C Crystal structure of FMN-binding beta-glucuronidase from Ruminococcus gnavus [[Ruminococcus] gnavus]
6D7J_A	1.07e-41	31	469	66	532	TheCrystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_B The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_C The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_D The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6DXU_A Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_B Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_C Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_D Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26257	6.61e-155	7	758	8	715	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
P77989	4.13e-154	5	778	7	724	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
Q59750	2.25e-87	6	758	7	715	Beta-galactosidase OS=Rhizobium meliloti OX=382 GN=lacZ PE=1 SV=1
T2KPJ7	9.88e-43	31	454	80	518	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
A7LXS9	4.40e-30	39	425	73	525	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000044	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000039_01734.