CAZyme Information: MGYG000000043_02308

Basic Information

• Species: Phocaeicola sp900066455
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900066455
• CAZyme ID: MGYG000000043_02308
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
989	MGYG000000043_27|CGC1	109608.2	6.7294

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000043	4183533	Isolate	United Kingdom	Europe

• Gene Location: Start: 2367; End: 5336 Strand: +

Full Sequence      

MKRQVLCSVVLCLLAVAGISAQGPALLNGIRDTAACRKWVDRQMERMTLKQKVGQLFIYT
LQPVVTQYNKNVLRKAVEDYAVGGLLFTGGEARKQVQLTNYAQSYASVPLMVTFDGEWGL
GMRLKGTPSFPYNRVLGCIQNDSLLYAYGKEVARQCHTVGVQVNFAPVADVDNNPQNPVI
NFRSFGSDPKRVADKVVSYTRGLEEGGVLAVCKHFPGHGDTEIDSHKALPELSFDRSRLD
SIELYPFRKAIEAGIGGVMVGHLHAPVLGEEPASISQQVIMHTLIEELRFQGLVVTDALE
MKGIAGHDDVCALALMAGNDMLLAPRNLKKEIDGVMTALKKGTLSKEEIDRKCRKVLTFK
YALGLSDWHDVAEDGIEEKLQTPELSELQQELAKAAVTVLKDSSALLPLDLSVSGTVLLS
VSSSLSEAYPFYNQLHQGFPLSWIHADADSLEVIATRLRPAQRILVALHSQEVEPYASLL
ENLAADKPLALVCFEDMKVLEKIPEAVRHASTVVLAHSDEAYLQREVADLFLGNACANGR
LSIPLAGMFKAGSGITIDPDAPRKYCPADLGMDASILAHIDSIAEEGIRLGAYPGCHVMV
LREGLPVYNKCFGYYTYEGKNPVKENSLYDLASLTKVTATLLAVMKLYDEGKFGLTDRVS
DYLPVLKKTDKSRITVQDLLFHESGLPAYLPFYEEAVDMKSCKGELFRKKPDKNHTLKLA
ENVYACNDFRYNPEWVSHTPSAEYSLQVADSLFLKPEFSQHVMEQIVKAPLKGKSYRYSC
LNFMLLKEMVEKITGMPMDLYLDSVFYTPMGLRHTAFRPLRKFAKEEIVPSVKEDYLRGG
LLQGFVQDEAAAFMGGVSGNAGLFATAHDVAKIAQMWLDKGVCGDRRYLSRATCELFMTL
KSRSSRRGLGFDKPDVDHPENSPCTPEAPASVFGHTGYTGTCVWVDPEHELVFVFLSNRT
YPSALGPNNLVRYNIRTRIQQAMYQSLMR

Enzyme Prediction     

No EC number prediction in MGYG000000043_02308.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	103	323	4.5e-54	0.9768518518518519

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00933	Glyco_hydro_3	3.05e-71	48	358	1	315	Glycosyl hydrolase family 3 N terminal domain.
COG1472	BglX	3.14e-71	47	414	1	355	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
PRK03642	PRK03642	2.75e-60	567	967	30	403	putative periplasmic esterase; Provisional
pfam00144	Beta-lactamase	2.64e-46	580	962	1	311	Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
COG1680	AmpC	5.30e-43	548	962	7	366	CubicO group peptidase, beta-lactamase class C family [Defense mechanisms].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QRO23705.1	0.0	11	987	10	986
ADY37542.1	0.0	8	989	4	987
ALA72189.1	0.0	1	989	1	992
AII66347.1	0.0	1	989	1	992
QJR54154.1	0.0	1	989	1	992

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	7.19e-56	47	545	11	531	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3SQL_A	9.78e-56	44	356	12	342	CrystalStructure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQL_B Crystal Structure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQM_A Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_B Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_C Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_D Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002]
4GYJ_A	1.67e-55	17	408	12	450	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
3BMX_A	9.39e-55	29	408	20	446	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	6.92e-54	34	408	1	420	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	5.14e-54	29	408	20	446	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
Q8Z4S7	1.53e-42	567	967	30	403	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella typhi OX=90370 GN=yfeW PE=3 SV=1
B5BB26	2.07e-42	567	967	30	403	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella paratyphi A (strain AKU_12601) OX=554290 GN=yfeW PE=3 SV=1
B5RCU8	2.07e-42	567	967	30	403	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=yfeW PE=3 SV=1
Q5PCQ2	2.07e-42	567	967	30	403	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) OX=295319 GN=yfeW PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000190	0.999251	0.000148	0.000145	0.000132	0.000129

TMHMM  Annotations     

start	end
5	27