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CAZyme Information: MGYG000000043_02527

You are here: Home > Sequence: MGYG000000043_02527

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola sp900066455
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900066455
CAZyme ID MGYG000000043_02527
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
726 MGYG000000043_32|CGC1 83196.7 6.2717
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000043 4183533 Isolate United Kingdom Europe
Gene Location Start: 31441;  End: 33621  Strand: -

Full Sequence      Download help

MKTRKTFAFV  AMCCCAFLAH  AQKLTSPDGN  LVMDFSLNQK  GAPVYELTFK  NKQVIKPSTL60
GLELKRENPE  KRIGFEWTER  KDKERVDEKT  NLMTGFKVRE  THTSTFDETW  RPVWGEESEI120
RNHYNELEVT  LDQPENDRYI  VIRFRLFNDG  LGFRYEFPQQ  KNLNYFVIKE  EHTQFAMTGD180
HTAFWIPGDY  DTQEYDYTTS  RLSEIRGKMK  EAVTENSSQF  VFSPTGVQTA  LMMKTDDGLY240
INLHEAALKD  YSCMSLNLDD  KNLVFESWLT  PDAKGDKGYM  QTPCTSPWRT  VIVSDDARNI300
LASRITLNLN  EPCKIADTSW  IHPVKYIGIW  WDMITNKGTW  AYTDDLASVK  LGETDYSKTK360
PNGKHSANTA  NVKRYIDFAA  ENGFDAVLVE  GWNQGWEDWF  GKSKDYVFDF  VTPYPDFDVE420
EVHRYAASKG  VEMIMHHETS  ASVRNYERHM  DKAYQFMVDN  GYHAVKSGYV  GDIIPRGEHH480
YGQWMVDHYL  YAVKKAADYK  IMVNAHEAVR  PTGLCRTYPN  LIGNESARGT  EYESFGGNNV540
NHTTILPFTR  LIGGPMDYTP  GIFEPDCSKM  NPNNKSHART  TLARQLALYV  TMYSPLQMAA600
DVPENYERFM  DAFQFIKDVA  VDWDETKYLE  AEPGEYITIA  RRAKGSTDWY  VGCTAGYNGH660
ESKLSLDFLQ  PGKKYEATIY  ADAKDASWDK  NPQAYTITKK  KVTNKTKLNL  KAAVGGGYAI720
SIKEVK726

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367210814518121725429032636339943547150854458061765368911722GH97
Family Start End Evalue family coverage
GH97 11 722 3.1e-260 0.9920760697305864

CDD Domains      download full data without filtering help

Created with Snap3672108145181217254290326363399435471508544580617653689317620Glyco_hydro_9726312GH97_N623723GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 2.39e-148 317 620 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 3.34e-102 26 312 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 1.77e-38 623 723 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap36721081451812172542903263633994354715085445806176536891726ADY34774.1|GH971726QRO24575.1|GH971726QQY42440.1|GH971726QUT56104.1|GH971726AND18771.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
ADY34774.1 0.0 1 726 1 726
QRO24575.1 0.0 1 726 1 726
QQY42440.1 0.0 1 726 1 727
QUT56104.1 0.0 1 726 1 727
AND18771.1 0.0 1 726 1 727

PDB Hits      download full data without filtering help

Created with Snap3672108145181217254290326363399435471508544580617653689227262D73_A237262JKA_A227263WFA_A267235HQ4_A267235HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 22 726 23 727
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 23 726 13 716
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 22 726 3 707
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 1.27e-169 26 723 5 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 1.27e-169 26 723 5 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36721081451812172542903263633994354715085445806176536891726sp|G8JZS4|SUSB_BACTN5723sp|Q8A6L0|AGAL_BACTN19666sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 1 726 1 727
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 1.78e-66 5 723 2 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 1.50e-28 19 666 28 574
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000850 0.853495 0.144689 0.000320 0.000347 0.000289

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000043_02527.