dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000043_02957

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Basic Information help

Species

Phocaeicola sp900066455

Lineage

Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900066455

CAZyme ID

MGYG000000043_02957

CAZy Family

GT51

CAZyme Description

Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
640		73022.27	7.035

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000043	4183533	Isolate	United Kingdom	Europe

Gene Location

Start: 26809; End: 28731 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000043_02957.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GT51	427	587	3.3e-45	0.8870056497175142

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00912	Transgly	2.24e-48	414	599	1	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
PRK00056	mtgA	5.92e-46	432	602	64	227	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional
COG0744	MrcB	1.22e-44	429	610	77	252	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02070	mono_pep_trsgly	1.05e-39	432	573	59	198	monofunctional biosynthetic peptidoglycan transglycosylase. This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
TIGR02074	PBP_1a_fam	3.73e-36	430	610	4	177	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QRO24561.1	1.95e-300	1	638	1	639
ADV42290.1	8.51e-254	2	638	18	665
ALJ61545.1	1.60e-247	14	627	1	623
QUT92885.1	3.00e-245	14	627	1	623
QDO71568.1	8.55e-245	14	627	1	623

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3NB6_A	6.01e-27	423	610	15	195	Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus]
2OQO_A	2.08e-26	423	610	15	195	Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus]
5U2G_A	3.88e-18	423	607	35	213	2.6Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20],5U2G_B 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20]
3DWK_A	1.10e-16	418	573	18	170	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
4OON_A	1.82e-16	436	573	47	182	Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q13U46	9.08e-31	430	600	72	235	Biosynthetic peptidoglycan transglycosylase OS=Paraburkholderia xenovorans (strain LB400) OX=266265 GN=mtgA PE=3 SV=1
B2SYS3	1.10e-29	434	600	76	235	Biosynthetic peptidoglycan transglycosylase OS=Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) OX=398527 GN=mtgA PE=3 SV=1
O24849	1.88e-29	422	579	52	204	Biosynthetic peptidoglycan transglycosylase OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) OX=62977 GN=mtgA PE=3 SV=1
B7GXW9	3.59e-29	422	579	49	204	Biosynthetic peptidoglycan transglycosylase OS=Acinetobacter baumannii (strain AB307-0294) OX=557600 GN=mtgA PE=3 SV=1
B2HVP6	3.59e-29	422	579	49	204	Biosynthetic peptidoglycan transglycosylase OS=Acinetobacter baumannii (strain ACICU) OX=405416 GN=mtgA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999039	0.000701	0.000161	0.000005	0.000003	0.000125

TMHMM Annotations download full data without filtering help

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