CAZyme Information: MGYG000000049_01727

Basic Information

• Species: GCA-900066495 sp900066495
• Lineage: Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; GCA-900066495; GCA-900066495 sp900066495
• CAZyme ID: MGYG000000049_01727
• CAZy Family: CBM51
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
2132	MGYG000000049_4|CGC3	242574.98	4.7346

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000049	3389401	Isolate	United Kingdom	Europe

• Gene Location: Start: 74755; End: 81153 Strand: +

Full Sequence      

MKKKLASILAISIIATNTTPTINVFADEIVRNKATSIEKEVNKNMTVETFKIKNYENFAR
YNDSYKVNIKSITNNGGKYNQSIITNAIDGKLETHWETGRENKADFKNEVEFEFENIEKI
NRLAYATRQDGARPKGYPKVAQILVTDSDESEYTLVGEVASNRVTGDMVEFKFDTVEAKK
VKFIFSDAHDGWASASEFWFYKEDKILDKMENIFTNDDMNEVNPEFTNLESLKSLEKEAK
NHPFYTNFKEDIYNAITILEGEKLESTLAKVSKLTAYGTEYQDDYNEKFMIPTSKITKVE
ANGGIYPGTKYEYMFDGDPNTHWETNKSNSMDFTNEITLTLDEAQIIDRLAYKARSSNNK
GFPTKFEIQVSETSKGETFQTIATGEAKVTSDMVEFKFAPTKAKRVKLVFNECNTGRAFA
SEIRLYKKDELSEKYSTLFTNDKKNEISSEFNSIDKLENFAKELEQHPLYNLYKEGINDA
RLILENKKVTYVDARVSKFKAFGSPELAEYDKAYKIDNSRIVNITTNGGHYSNEVIARAI
DGNIETSWHSSKTNNENHINEVTMTLDQLETIDKIVYTSPRARGFAEEFDIYVSKTLEGE
TFEKVTSGRSSRTNDSVSIKFNPTEARRVKFLYTKAYENFALAYEFGLYKQDPIIDKMDN
LFIDETMSKVSEEFANIEALNRLEDEVKVHPFYEDFREDIENAKALVEQGEIEATVSKTK
KFNHYNNKEYMEQYAIKRENIKKISNNGGQWSTMKIDNAIDGDLDTYWETNTSNKEDWKN
EVTVEFINPITIDKLVYGARKSDRKGFLEEFEIYASTTTKGDNFKLVSTAKSDKTTGLVE
AKFEPTKFQRLRIKVTKGDQNWATLNELIFLKEDSIADKVYNMFINDLMNELVDDYDTIE
EIESLEREVSTHSLKEELMEYIKRAKEIVKNPEQAKEYVYELESRGDSIKESQKRQMWNF
QDWQPTGLAVKSGQQITVYVDSEPGTPTPRLVFKQMDSQHNGNVNLNLSPGKNVITIPEL
DSNELRPNVAKAGVLYTVNPYTKDQQIRNPKIKIEGAFEYPAFVLGQDDDEVIMKELEKY
TDKLKEDPTLPDVFEVFSKKNLVNTRATYALDWYKKNNLLPSYTANKVDEILAESMKFWG
FDGSNEVNSDYNYRYVSMLKWLDNGGFMNAGNGITGYNQNEQGAVLGYNTGWGLMHELGH
NMDTAKMSVVEVTNNMLPLHFEVLEGKVSRFTQQNKYKNNIFPKVTKADYSENIWYPEND
YTNLQHIAPLWQLQLYDETFWPRLQQEFRENPSLGGGNWDNKHQAWAVAASNVMQMDLTE
HFARHGFSVTKETEEHMKQYPKLAGKIWYMNDNKYLKDGETFNEDFDLKLHTKINKENIT
LTMELDKENNKSLLGYEIYRDGKLIGFTNTETYVDKEANIGTNHNYEVVAFSNDLNVAEG
VTVKSHQPKLDVQKDIVIELNKDFNALDYVEAFDYEGNKLNNITVEHNVDTSRKGEYEVT
YKITQDGATLTDTTTVTVVSDFTYLTDLKHEDVKVGWGSPKFNKDIYGRVNGISKKFQKG
IGLHANGYVVYNLGEHNYDTLDIKLGTDSSKADSRTTLDFKIIGDGKVLAKTDIKRYTDD
LEHIKLNISDVKELRIEVSIAGDSDANDHGIIVEPKLIGNNSKPVINIDESQSIKVGDTL
ENVIGNIEATDKEDGNLTKNVKISGQDKVNTNRVGIYPITYTVEDSDGNITVATRNIKVV
NMDDFTYLSDYNWKSQSNNYTQAKKDVAISGRKLTLTGENNEAVEYEKGLGMHSTSTVIY
DLTDKNADIFSTYIGVDRAMYNSVGQVQFEIYVDGKLAYDSGIIRAKDKQKYIEVNLADA
KELKLVVKDGGNGNGSDHATFGDAKLHFVNTSRVDKTELTNLVNDAKNLNEDNYLEESFN
AMQIVLVKAERVLEDNSASQEDVDNVSSELKESIKELTEINLDEVVNIPDKYLAKFLSNA
LGKSEGFTVADMRSLTELSLSGVTNLEGLQYANNLVSIESEYNEIKDLRPLAKLKNLEKA
NFKNQFVSVGELSVVDGSVTVNTEAYNRAGKNVATKVVLVDRNGNVLKEEAVNNAAEISL
DVSSLERGIYGVHVSYEDDEISGILMNIATIK

Enzyme Prediction     

No EC number prediction in MGYG000000049_01727.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM51	1746	1886	9.5e-42	0.9925373134328358
CBM51	1523	1657	2.7e-26	0.9925373134328358

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam08305	NPCBM	1.10e-48	1746	1887	3	136	NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.)
smart00776	NPCBM	3.38e-40	1746	1887	5	145	This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.
pfam08305	NPCBM	4.36e-31	1523	1658	3	136	NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.)
smart00776	NPCBM	4.93e-24	1523	1657	5	144	This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.
pfam13402	Peptidase_M60	1.35e-14	1056	1322	1	264	Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CEI71816.1	0.0	1	2132	1	2131
AIY84110.1	0.0	265	2120	41	1911
AQW26342.1	0.0	1	2118	1	2127
AOY53509.1	0.0	1	2118	1	2127
AMN32462.1	0.0	1	2118	1	2127

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7JFS_A	4.41e-282	494	1443	27	980	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
7JS4_A	7.55e-242	939	1886	24	975	ChainA, F5/8 type C domain protein [Clostridium perfringens ATCC 13124]
6XSX_A	6.33e-222	939	1444	24	529	ChainA, ZmpA Glycopeptidase [Clostridium perfringens ATCC 13124]
5KDJ_A	1.15e-174	871	1520	21	672	ZmpBmetallopeptidase from Clostridium perfringens [Clostridium perfringens ATCC 13124],5KDJ_B ZmpB metallopeptidase from Clostridium perfringens [Clostridium perfringens ATCC 13124]
5KDN_A	4.22e-153	939	1443	24	529	ZmpBmetallopeptidase from Clostridium perfringens [Clostridium perfringens ATCC 13124],5KDS_A ZmpB metallopeptidase in complex with an O-glycopeptide (a2,6-sialylated core-3 pentapeptide). [Clostridium perfringens ATCC 13124],5KDU_A ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen [Clostridium perfringens ATCC 13124]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001248	0.997555	0.000326	0.000323	0.000265	0.000235

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000049_01727.