CAZyme Information: MGYG000000052_00773

Basic Information

• Species: Anaerostipes sp000508985
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes; Anaerostipes sp000508985
• CAZyme ID: MGYG000000052_00773
• CAZy Family: GT5
• CAZyme Description: Glycogen synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
483	MGYG000000052_3|CGC1	55350.18	5.8919

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000052	3273906	Isolate	United Kingdom	Europe

• Gene Location: Start: 142062; End: 143513 Strand: +

Full Sequence      

MNKRNECMMNVLMVAAECAPFVKLGGLADVIGTLPKELNKLHVDTRVMMPFHRQIKDKYA
AQTKHMADFYIHFAGRDVYVGVEGLFFNDVTYYFIDNEEYFGDAVYRGGDAEGEQYAYFC
RAVIEAAGRIGFLPNVLHCNDWQTGLIPLLLKTQYSHWEIGRARTIFTIHNMMYQGEYAF
EAFHHWLGIDPRYDTPEFMHNYECASFMKAALVFADRISTVSPTYAQEIKTPEFAYRLEG
ILNARAWDTWGIVNGINTEEFDPETDPYLQYHFNKDDLTGKKKNKEKLISDLGLSISPGV
PIIGMVSRLTAQKGLDLVKYILDELMCTEDIAFVVLGTGDHDYEEFFRFMENKYKGRVCS
YIAYNNAVAHQIYAASDLFLMPSKFEPCGISQMIALRYGTLPIVRETGGLCDTVQSYNEF
EETGNGFSFRNYNAHEMLSIIRYALNTLRSPKRRKGLIQRAMESDNSFGSSAKKYLELYQ
SIL

Enzyme Prediction     

No EC number prediction in MGYG000000052_00773.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT5	10	480	4.1e-173	0.9957627118644068

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0297	GlgA	0.0	9	483	1	479	Glycogen synthase [Carbohydrate transport and metabolism].
TIGR02095	glgA	0.0	9	482	1	473	glycogen/starch synthase, ADP-glucose type. This family consists of glycogen (or starch) synthases that use ADP-glucose (EC 2.4.1.21), rather than UDP-glucose (EC 2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
PRK00654	glgA	0.0	9	483	1	464	glycogen synthase GlgA.
cd03791	GT5_Glycogen_synthase_DULL1-like	0.0	10	481	1	474	Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
PRK14099	PRK14099	4.39e-105	9	483	4	480	glycogen synthase GlgA.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCD36165.1	0.0	1	483	1	483
QMW73020.1	0.0	9	483	1	475
QCP35770.1	0.0	8	483	1	476
AQP40141.1	2.59e-290	5	483	3	481
CBL37812.1	1.05e-289	5	483	3	481

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4HLN_A	6.70e-81	10	480	126	623	Structureof barley starch synthase I in complex with maltooligosaccharide [Hordeum vulgare]
3D1J_A	1.18e-76	9	479	1	473	ChainA, Glycogen synthase [Escherichia coli]
2QZS_A	2.05e-76	9	479	1	473	CrystalStructure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSb) [Escherichia coli],2R4T_A Crystal Structure of Wild-type E.coli GS in Complex with ADP and Glucose(wtGSc) [Escherichia coli],2R4U_A Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSd) [Escherichia coli],3GUH_A Crystal Structure of Wild-type E.coli GS in complex with ADP and DGM [Escherichia coli K-12]
6GNE_A	7.25e-76	11	479	12	494	Catalyticdomain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana],6GNE_B Catalytic domain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana]
3COP_A	1.57e-75	9	479	1	473	ChainA, Glycogen synthase [Escherichia coli],3CX4_A Chain A, Glycogen synthase [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A4IS20	1.73e-153	9	483	1	475	Glycogen synthase OS=Geobacillus thermodenitrificans (strain NG80-2) OX=420246 GN=glgA PE=3 SV=1
O08328	6.95e-153	9	483	1	475	Glycogen synthase OS=Geobacillus stearothermophilus OX=1422 GN=glgA PE=3 SV=1
C4Z0G2	4.69e-149	8	482	1	478	Glycogen synthase OS=Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4) OX=515620 GN=glgA PE=3 SV=1
B7GK04	3.59e-142	9	483	1	475	Glycogen synthase OS=Anoxybacillus flavithermus (strain DSM 21510 / WK1) OX=491915 GN=glgA PE=3 SV=1
Q97GX6	1.20e-138	9	483	1	477	Glycogen synthase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) OX=272562 GN=glgA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000051	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000052_00773.