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CAZyme Information: MGYG000000054_01470

You are here: Home > Sequence: MGYG000000054_01470

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides acidifaciens
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides acidifaciens
CAZyme ID MGYG000000054_01470
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
736 MGYG000000054_13|CGC1 83932.69 6.5098
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000054 5213730 Isolate United Kingdom Europe
Gene Location Start: 11771;  End: 13981  Strand: +

Full Sequence      Download help

MKKKLLLIVC  LCISYITNAQ  QRLTSPDGNL  VMTFQVDKEG  APTYDLTYKG  KTVIKPSTLG60
LELKKEDNTR  TDFDWVDRRD  LTKLDSKTNL  YNGFEVKDIK  TSTFDETWQP  VWGEEKEIRN120
HYNELAATLY  QPMNERSILI  RFRLFNDGLG  FRYEFPQQKN  LNYFIVKEEH  SQFAMAGDHI180
AYWIPGDYDT  QEYDYTISRL  SEIRGLMKQA  VTPNSSQTPF  SQTGVQTALM  MKTDDGLYIN240
LHEAALIDYS  CMHLNLNDQN  MTFESWLTPD  AKGDKGHLQT  PCNTPWRTVI  VSDDARNILA300
SRITLNLNEP  CKIADAASWV  KPVKYIGVWW  DMITGKGSWA  YTDELTSVKL  GETDYSKTKP360
NGKHSANTAN  VKRYIDFAAA  NGFDAVLVEG  WNEGWEDWFG  NSKDYVFDFV  TPYPDFDVKE420
VHRYAASKGI  KMMMHHETSS  SVRNYERHID  KAYQFMVDNG  YNSVKSGYVG  NIIPRGEHHY480
GQWMNNHYLY  AVKKAADYKI  MVNAHEATRP  TGICRTYPNL  IGNESARGTE  YEAFGGNKVY540
HTTILPFTRL  VGGPMDYTPG  IFETHCNKMN  PANNSQVRST  IARQLALYVT  MYSPLQMAAD600
IPENYERFMD  AFQFIKDVAI  DWDETNYLEA  EPGEYITIAR  KAKGTDDWYV  GCTAGENGHT660
SRLVFDFLTP  GKQYIATVYA  DAKDADWKEN  PQAYTITKGI  LTSKSKLNLR  AANGGGYAIS720
IKEVKDKAEV  KGMKKL736

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap36731101471842202572943313684044414785155525886256626999721GH97
Family Start End Evalue family coverage
GH97 9 721 1.2e-252 0.993660855784469

CDD Domains      download full data without filtering help

Created with Snap3673110147184220257294331368404441478515552588625662699318619Glyco_hydro_9725310GH97_N622722GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 2.84e-144 318 619 3 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 2.20e-99 25 310 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 2.48e-43 622 722 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap36731101471842202572943313684044414785155525886256626991735QIU94095.1|GH971735QUT26955.1|GH971735QUT32479.1|GH971735QDH54124.1|GH971735QRM98896.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
QIU94095.1 0.0 1 735 1 735
QUT26955.1 0.0 1 735 1 735
QUT32479.1 0.0 1 735 1 735
QDH54124.1 0.0 1 735 1 735
QRM98896.1 0.0 1 735 1 735

PDB Hits      download full data without filtering help

Created with Snap3673110147184220257294331368404441478515552588625662699177362D73_A227362JKA_A207363WFA_A257225HQ4_A257225HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 17 736 19 738
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 22 736 13 727
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 20 736 2 718
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 1.24e-169 25 722 5 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 1.24e-169 25 722 5 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36731101471842202572943313684044414785155525886256626992736sp|G8JZS4|SUSB_BACTN1722sp|Q8A6L0|AGAL_BACTN40663sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 2 736 3 738
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 9.76e-64 1 722 1 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 4.98e-29 40 663 57 572
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000405 0.998734 0.000297 0.000176 0.000185 0.000177

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000054_01470.