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CAZyme Information: MGYG000000054_01657

You are here: Home > Sequence: MGYG000000054_01657

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides acidifaciens
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides acidifaciens
CAZyme ID MGYG000000054_01657
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
719 MGYG000000054_15|CGC1 81491.97 5.867
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000054 5213730 Isolate United Kingdom Europe
Gene Location Start: 83022;  End: 85181  Strand: -

Full Sequence      Download help

MKNMKTGTAM  WLCLLLAFLV  GTSAKAESIT  SPDGQLKLDF  SVNAQGEPVY  ELSYKGKEVI60
KPSGLGLELK  NDPGLMNGFT  LADTRTSTFD  ETWEPVWGEV  KSIRNYYNEM  AVTLNQKIQE120
RSIIIRFRLY  NDGLGFRYEF  PLQKNLNYFV  IKEEHSQFAM  AGDHTAFWIP  GDYDTQEYDY180
TESKLSEIRG  LLQGAITGNA  SQTSFSPTGV  QTSLQMKTAN  GLYINLHEAA  LVDYSCMHLN240
LDDKNLIFES  WLTPDAKGDK  GYMQAPCRSP  WRTVIVSDDA  RDILASKLTL  NLNEPCAYED300
VSWIKPVKYI  GVWWEMISGK  SSWAYTDDVY  SVKLGETDYS  KTKPNGRHAA  NNDNVKRYID360
FASLHGFDQV  LVEGWNEGWE  DWFGHSKDYV  FDFVTPYPDF  DLKMLNAYAK  AKGVKLMMHH420
ETSASARNYE  RHLDTAYQFM  VDNGYDAVKS  GYVGNIIPRG  EHHYGQWMND  HYLYAVKKAA480
DYKICVNAHE  AVRPTGLCRT  YPNLIGNESA  RGTEYEAFAG  NKPFHTTLLP  FTRLIGGPMD540
YTPGIFDTKL  SFLQGDHSFV  RTTLAKQLAL  YVTMYSPLQM  AADFPENYER  HLDAFQFIKD600
VALDWDDSKY  LEAEPGDYIT  VARKAKGTDN  WFVGGITDEN  PRTSTFALDF  LEPGKQYVAT660
LYEDGKDADF  EKNPTSYQIK  KGIVTAKTRI  SAKLARSGGF  ALSLIEATPA  DRKIIKKWK719

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap357110714317921525128732335939543146750353957561164768315704GH97
Family Start End Evalue family coverage
GH97 15 704 4.8e-259 0.993660855784469

CDD Domains      download full data without filtering help

Created with Snap3571107143179215251287323359395431467503539575611647683300602Glyco_hydro_9731295GH97_N605705GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 7.87e-145 300 602 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 5.19e-103 31 295 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 2.40e-46 605 705 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap35711071431792152512873233593954314675035395756116476831719QIU95032.1|GH971719QUT27779.1|GH971719QDH54929.1|GH971719QUT82802.1|GH971719QDM12043.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
QIU95032.1 0.0 1 719 1 719
QUT27779.1 0.0 1 719 1 719
QDH54929.1 0.0 1 719 1 719
QUT82802.1 0.0 1 719 1 719
QDM12043.1 0.0 1 719 1 719

PDB Hits      download full data without filtering help

Created with Snap3571107143179215251287323359395431467503539575611647683277062D73_A297062JKA_A277063WFA_A287025HQ4_A287025HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 27 706 23 725
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 29 706 14 714
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 27 706 3 705
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 5.69e-172 28 702 2 656
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 5.69e-172 28 702 2 656
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap357110714317921525128732335939543146750353957561164768315706sp|G8JZS4|SUSB_BACTN4704sp|Q8A6L0|AGAL_BACTN21701sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 15 706 9 725
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 5.52e-65 4 704 1 661
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 7.95e-27 21 701 39 617
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000251 0.999039 0.000187 0.000182 0.000170 0.000154

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000054_01657.