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CAZyme Information: MGYG000000054_03257

You are here: Home > Sequence: MGYG000000054_03257

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides acidifaciens
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides acidifaciens
CAZyme ID MGYG000000054_03257
CAZy Family CBM50
CAZyme Description Integration host factor subunit alpha
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
477 MGYG000000054_51|CGC1 53812.98 4.4032
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000054 5213730 Isolate United Kingdom Europe
Gene Location Start: 10570;  End: 12003  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000054_03257.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam00216 Bac_DNA_binding 1.97e-17 6 93 1 88
Bacterial DNA-binding protein.
COG0776 HimA 4.29e-15 5 96 2 93
Bacterial nucleoid DNA-binding protein [Replication, recombination and repair].
smart00411 BHL 2.17e-13 5 94 1 90
bacterial (prokaryotic) histone like domain.
cd13831 HU 1.85e-12 8 91 3 86
histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.
cd13832 IHF 9.53e-12 9 91 3 85
Integration host factor (IHF) and similar proteins. This subfamily includes integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms. This subfamily also includes the protein Hbb from tick-borne spirochete Borrelia burgdorferi, responsible for causing Lyme disease in humans. Hbb, a homodimer, shows DNA sequence preferences that are related, yet distinct from those of IHF.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QNL37743.1 1.26e-157 1 477 1 471
QUT81732.1 2.35e-155 1 477 1 471
QRQ57020.1 2.35e-155 1 477 1 471
QGT70075.1 4.71e-155 1 477 1 471
QUR43014.1 2.69e-154 1 477 1 471

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5J0N_I 3.44e-08 5 93 2 90
ChainI, Integration host factor subunit alpha [Escherichia coli],5J0N_K Chain K, Integration host factor subunit alpha [Escherichia coli]
1IHF_A 3.71e-08 5 93 3 91
INTEGRATIONHOST FACTOR/DNA COMPLEX [Escherichia coli],1OUZ_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWF_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWG_A Crystal structure of WT IHF complexed with an altered H' site (T44A) [Escherichia coli],2HT0_A IHF bound to doubly nicked DNA [Escherichia coli],5WFE_K Cas1-Cas2-IHF-DNA holo-complex [Escherichia coli S88]
2IIE_A 2.68e-07 5 93 47 135
singlechain Integration Host Factor protein (scIHF2) in complex with DNA [Escherichia coli]
2IIF_A 8.90e-07 5 93 47 135
ChainA, Integration host factor [Escherichia coli]
5LVT_A 2.41e-06 8 93 5 90
Structureof HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_B Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_C Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403],5LVT_D Structure of HU protein from Lactococcus lactis [Lactococcus lactis subsp. lactis Il1403]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q65TL4 1.35e-09 5 95 3 93
Integration host factor subunit alpha OS=Mannheimia succiniciproducens (strain MBEL55E) OX=221988 GN=ihfA PE=3 SV=1
Q9CN18 2.52e-09 5 95 3 93
Integration host factor subunit alpha OS=Pasteurella multocida (strain Pm70) OX=272843 GN=ihfA PE=3 SV=1
B5FDX6 1.63e-08 5 90 3 88
Integration host factor subunit alpha OS=Aliivibrio fischeri (strain MJ11) OX=388396 GN=ihfA PE=3 SV=1
Q5E5G4 1.63e-08 5 90 3 88
Integration host factor subunit alpha OS=Aliivibrio fischeri (strain ATCC 700601 / ES114) OX=312309 GN=ihfA PE=3 SV=1
B6EN06 1.63e-08 5 90 3 88
Integration host factor subunit alpha OS=Aliivibrio salmonicida (strain LFI1238) OX=316275 GN=ihfA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000043 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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