dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000055_00054

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Basic Information help

Species

Muribaculum intestinale

Lineage

Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; Muribaculum; Muribaculum intestinale

CAZyme ID

MGYG000000055_00054

CAZy Family

GH2

CAZyme Description

Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1135		126365.78	6.0647

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000055	3235245	Isolate	United Kingdom	Europe

Gene Location

Start: 66685; End: 70092 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000055_00054.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH2	73	506	8.9e-74	0.4946808510638298

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	3.39e-31	130	483	103	439	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	2.89e-21	106	520	62	479	beta-D-glucuronidase; Provisional
pfam07691	PA14	3.79e-21	854	985	6	140	PA14 domain. This domain forms an insert in bacterial beta-glucosidases and is found in other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins, including anthrax protective antigen (PA). The domain also occurs in a Dictyostelium prespore-cell-inducing factor Psi and in fibrocystin, the mammalian protein whose mutation leads to polycystic kidney and hepatic disease. The crystal structure of PA shows that this domain (named PA14 after its location in the PA20 pro-peptide) has a beta-barrel structure. The PA14 domain sequence suggests a binding function, rather than a catalytic role. The PA14 domain distribution is compatible with carbohydrate binding.
PRK10340	ebgA	2.25e-17	115	482	115	470	cryptic beta-D-galactosidase subunit alpha; Reviewed
smart00758	PA14	2.82e-16	843	984	7	135	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.

CAZyme Hits help

Hit ID	Query Start	Query End	Hit Start	Hit End
ANU64711.2	1	1135	1	1135
QQR09994.1	1	1135	1	1135
ASB36840.1	1	1135	1	1135
QQA08720.1	29	1128	26	1127
QMW85532.1	29	1128	26	1127

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ED1_A	4.12e-26	108	522	76	490	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei]
4YPJ_A	3.22e-22	109	486	70	441	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
6D7J_A	1.31e-21	73	453	46	430	TheCrystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_B The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_C The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6D7J_D The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site [Parabacteroides merdae CL03T12C32],6DXU_A Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_B Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_C Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184],6DXU_D Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) [Parabacteroides merdae ATCC 43184]
6B6L_A	2.23e-19	88	485	48	435	Thecrystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838],6B6L_B The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838]
7RSK_A	3.88e-19	88	485	48	435	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7RSK_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KM09	7.53e-22	109	489	106	459	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
P26257	3.33e-18	130	482	75	411	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
P77989	1.05e-17	105	453	52	388	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KN75	2.68e-16	105	448	83	433	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
Q56307	2.50e-15	102	469	105	458	Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.002309	0.858914	0.137844	0.000322	0.000303	0.000283

TMHMM Annotations help

There is no transmembrane helices in MGYG000000055_00054.