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CAZyme Information: MGYG000000057_00290
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides sp002491635 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp002491635 | |||||||||||
| CAZyme ID | MGYG000000057_00290 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Retaining alpha-galactosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 57313; End: 59262 Strand: - | |||||||||||
Full Sequence Download help
| MKKQLLLPAA LCLSLTIFGQ KVHQLTSPSG NIRISLELTD QIRYDVAQGN QTLMDSCVIG | 60 |
| LETANRQLGI HPKLDKAVRQ SVNEELTPVV PLKFSTVTNR YNRLLLKFKG DYSVEFRAFD | 120 |
| DGFAYRFLTD LKGEQEIINE ILRLNLVDGC LLHLQQPDGF KTSYEEEYRH QTCSEWKNSN | 180 |
| RMALLPLLAS TPEGDKILMS ETNLTDYPAM FLKNDGQGGI ASVFPRLPLE FGEDGDRSLK | 240 |
| ILKEANCIAR TAGKRSYPWR YFVITDDDRK LIENTLSYRL AEKNVIENTS WIKPGLASWE | 300 |
| WWNGAIPYGP DVDFKAGCNL DNYKYFIDFA SHYGIEYIVM DEGWAMNTRD PYTPNPTVDI | 360 |
| HELIRYGKEK NVGIVLWLTW LTVENHFDLF ETFEKWGVKG VKIDFMNRSD QWMVNFYERV | 420 |
| AREAAKHHLF VDFHGAFKPA GLEYKYPNVL SYEGVRGMEQ MGGCRPDNSV YFPFIRNAVG | 480 |
| AMDYTPGAML SMQPEVYRSE RPNSASIGTR AYQMALFVLF ETGLQMMADN PTLYYRNDEC | 540 |
| TRFITQVPQT WDETIALEAE AGEYAVVAKR KGEQWYIGGM TNNRERERVF NISLDFLQEG | 600 |
| KNYLMTSFED GINADHQAMD YRKQERTLKK GDRITVRLAR NGGFAAVIR | 649 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 12 | 648 | 3.4e-194 | 0.9920760697305864 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam10566 | Glyco_hydro_97 | 5.11e-132 | 289 | 548 | 2 | 278 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14508 | GH97_N | 2.05e-68 | 27 | 282 | 1 | 234 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
| pfam14509 | GH97_C | 4.97e-47 | 551 | 649 | 1 | 97 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QMI79902.1 | 0.0 | 1 | 649 | 1 | 649 |
| QBJ18497.1 | 0.0 | 1 | 649 | 1 | 649 |
| QPH58798.1 | 0.0 | 1 | 649 | 1 | 649 |
| QUT65772.1 | 0.0 | 1 | 649 | 1 | 649 |
| QQA30013.1 | 0.0 | 1 | 649 | 1 | 649 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3A24_A | 2.31e-134 | 23 | 649 | 2 | 641 | Crystalstructure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron],3A24_B Crystal structure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron] |
| 5E1Q_A | 3.85e-133 | 23 | 649 | 16 | 655 | Mutant(D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482],5E1Q_B Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482] |
| 5HQ4_A | 1.67e-54 | 27 | 645 | 5 | 655 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQC_A | 2.29e-54 | 27 | 645 | 5 | 655 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQB_A | 4.32e-54 | 27 | 645 | 5 | 655 | AGlycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8A6L0 | 9.55e-136 | 1 | 649 | 1 | 662 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| D7CFN7 | 3.29e-66 | 33 | 647 | 49 | 619 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
| G8JZS4 | 8.85e-49 | 1 | 649 | 1 | 724 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000366 | 0.998719 | 0.000327 | 0.000184 | 0.000177 | 0.000163 |