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CAZyme Information: MGYG000000076_01517

You are here: Home > Sequence: MGYG000000076_01517

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia intestinalis
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia intestinalis
CAZyme ID MGYG000000076_01517
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
292 MGYG000000076_10|CGC3 34158.76 6.3961
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000076 4318260 Isolate United Kingdom Europe
Gene Location Start: 80262;  End: 81140  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000076_01517.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 1 288 7.5e-53 0.9855072463768116

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.24e-41 1 273 1 249
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 3.77e-18 10 289 41 295
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.
cd11548 NodZ_like 0.003 8 268 8 284
Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
VCV23356.1 8.57e-216 1 292 1 292
CBL08052.1 8.57e-216 1 292 1 292
CBL12617.1 2.33e-213 1 292 67 358
AEN97523.1 7.67e-110 1 291 1 269
AMK78698.1 2.47e-30 1 275 1 269

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 5.48e-15 6 291 5 302
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000067 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000076_01517.