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CAZyme Information: MGYG000000076_02159

You are here: Home > Sequence: MGYG000000076_02159

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia intestinalis
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia intestinalis
CAZyme ID MGYG000000076_02159
CAZy Family CBM86
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1372 MGYG000000076_15|CGC2 150672.03 6.5415
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000076 4318260 Isolate United Kingdom Europe
Gene Location Start: 92275;  End: 96393  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH10 378 769 1.2e-79 0.9900990099009901
CBM9 929 1101 9e-54 0.9945054945054945
CBM86 57 166 1.1e-52 0.9906542056074766
CBM22 182 332 8.2e-24 0.9618320610687023

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd00005 CBM9_like_1 9.27e-83 919 1101 1 184
DOMON-like type 9 carbohydrate binding module of xylanases. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. The CBM9 domain frequently occurs in tandem repeats; members found in this subfamily typically co-occur with glycosyl hydrolase family 10 domains and are annotated as endo-1,4-beta-xylanases. CBM9 from Thermotoga maritima xylanase 10A is reported to have specificity for polysaccharide reducing ends.
pfam00331 Glyco_hydro_10 8.83e-65 388 768 13 310
Glycosyl hydrolase family 10.
smart00633 Glyco_10 3.50e-64 454 765 11 262
Glycosyl hydrolase family 10.
pfam06452 CBM9_1 5.69e-53 929 1101 1 181
Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.
cd20907 CBM86 1.36e-51 46 171 2 127
carbohydrate binding module family 86. This family describes what is most likely a xylan-binding module such as found in the Xyn10A protein of Roseburia intestinalis L1-82, which is involved in the extracellular capture and breakdown of xylan.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
VCV24088.1 0.0 1 1372 1 1372
CBL13458.1 0.0 17 1372 1 1356
EEV01588.1 0.0 17 1372 1 1356
QJU17095.1 6.64e-283 169 1103 217 1148
BAA09971.1 4.65e-256 181 1103 44 827

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6SGF_A 1.88e-85 44 181 4 141
Molecularinsight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82],6SGF_B Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82],6SGF_C Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82],6SGF_D Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82],6SGF_E Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82],6SGF_F Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. [Roseburia intestinalis L1-82]
2W5F_A 1.94e-49 223 763 57 521
ChainA, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus],2W5F_B Chain B, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus]
2WYS_A 1.39e-46 223 763 57 521
ChainA, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus],2WYS_B Chain B, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus],2WZE_A Chain A, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus],2WZE_B Chain B, ENDO-1,4-BETA-XYLANASE Y [Acetivibrio thermocellus]
1I82_A 2.13e-46 919 1101 2 187
Family9 Carbohydrate-Binding Module From Thermotoga Maritima Xylanase 10a With Cellobiose [Thermotoga maritima],1I8A_A Family 9 Carbohydrate-Binding Module From Thermotoga Maritima Xylanase 10a With Glucose [Thermotoga maritima],1I8U_A Family 9 Carbohydrate-Binding Module From Thermotoga Maritima Xylanase 10a [Thermotoga maritima]
6D5C_A 3.65e-42 371 769 16 350
Structureof Caldicellulosiruptor danielii GH10 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii],6D5C_B Structure of Caldicellulosiruptor danielii GH10 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii],6D5C_C Structure of Caldicellulosiruptor danielii GH10 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P36917 5.08e-101 182 1101 190 1042
Endo-1,4-beta-xylanase A OS=Thermoanaerobacterium saccharolyticum OX=28896 GN=xynA PE=1 SV=1
P38535 2.26e-94 182 1101 38 894
Exoglucanase XynX OS=Acetivibrio thermocellus OX=1515 GN=xynX PE=3 SV=1
Q60042 6.41e-94 137 1101 159 1053
Endo-1,4-beta-xylanase A OS=Thermotoga neapolitana OX=2337 GN=xynA PE=1 SV=1
O69230 4.80e-93 243 1101 250 1083
Endo-1,4-beta-xylanase C OS=Paenibacillus barcinonensis OX=198119 GN=xynC PE=1 SV=1
Q60037 2.73e-92 243 1101 255 1057
Endo-1,4-beta-xylanase A OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=xynA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.009196 0.986044 0.002505 0.001667 0.000321 0.000248

TMHMM  Annotations      download full data without filtering help

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