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CAZyme Information: MGYG000000076_02527
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Roseburia intestinalis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia intestinalis | |||||||||||
| CAZyme ID | MGYG000000076_02527 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | DNA mismatch repair protein MutS | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 59986; End: 68601 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG4646 | COG4646 | 5.64e-75 | 1576 | 2103 | 1 | 540 | Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]. |
| COG4646 | COG4646 | 1.02e-28 | 2244 | 2435 | 439 | 637 | Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]. |
| pfam01624 | MutS_I | 1.54e-22 | 992 | 1069 | 5 | 82 | MutS domain I. This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with pfam00488, pfam05188, pfam05192 and pfam05190. The MutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein. The aligned region corresponds with globular domain I, which is involved in DNA binding, in Thermus aquaticus MutS as characterized in. |
| PRK05399 | PRK05399 | 1.73e-20 | 992 | 1069 | 13 | 90 | DNA mismatch repair protein MutS; Provisional |
| COG0249 | MutS | 7.68e-17 | 985 | 1069 | 4 | 83 | DNA mismatch repair ATPase MutS [Replication, recombination and repair]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ASV45029.1 | 0.0 | 1280 | 2796 | 1548 | 3146 |
| QIW86704.1 | 4.57e-318 | 1280 | 2796 | 1616 | 3214 |
| QIW86628.1 | 4.57e-318 | 1280 | 2796 | 1616 | 3214 |
| AXF51455.1 | 1.49e-316 | 1280 | 2856 | 1782 | 3442 |
| AEY69616.1 | 5.03e-316 | 1280 | 2833 | 1689 | 3326 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1NNE_A | 4.77e-09 | 992 | 1070 | 18 | 95 | CrystalStructure of the MutS-ADPBeF3-DNA complex [Thermus aquaticus],1NNE_B Crystal Structure of the MutS-ADPBeF3-DNA complex [Thermus aquaticus] |
| 1EWQ_A | 2.43e-08 | 992 | 1070 | 18 | 95 | ChainA, DNA MISMATCH REPAIR PROTEIN MUTS [Thermus aquaticus],1EWQ_B Chain B, DNA MISMATCH REPAIR PROTEIN MUTS [Thermus aquaticus] |
| 1FW6_A | 2.44e-08 | 992 | 1070 | 18 | 95 | CRYSTALSTRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX [Thermus aquaticus],1FW6_B CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX [Thermus aquaticus] |
| 5AKB_A | 1.66e-07 | 988 | 1070 | 11 | 93 | MutSin complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKB_B MutS in complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKB_E MutS in complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKC_A MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_B MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_E MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_F MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_I MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_J MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKD_A MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_B MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_E MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_F MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_I MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_J MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12] |
| 7AI6_A | 1.70e-07 | 988 | 1070 | 11 | 93 | ChainA, DNA mismatch repair protein MutS [Escherichia coli K-12],7AI6_B Chain B, DNA mismatch repair protein MutS [Escherichia coli K-12],7AIB_A Chain A, DNA mismatch repair protein MutS [Escherichia coli K-12],7AIB_B Chain B, DNA mismatch repair protein MutS [Escherichia coli K-12],7AIC_A Chain A, DNA mismatch repair protein MutS [Escherichia coli K-12],7AIC_B Chain B, DNA mismatch repair protein MutS [Escherichia coli K-12] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B0S1C1 | 1.06e-11 | 987 | 1069 | 3 | 85 | DNA mismatch repair protein MutS OS=Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) OX=334413 GN=mutS PE=3 SV=1 |
| Q2LUL3 | 1.08e-11 | 988 | 1069 | 13 | 94 | DNA mismatch repair protein MutS OS=Syntrophus aciditrophicus (strain SB) OX=56780 GN=mutS PE=3 SV=1 |
| A4J5Q6 | 1.84e-11 | 988 | 1083 | 4 | 99 | DNA mismatch repair protein MutS OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=mutS PE=3 SV=1 |
| A1VDD9 | 2.47e-11 | 984 | 1069 | 5 | 90 | DNA mismatch repair protein MutS OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) OX=391774 GN=mutS PE=3 SV=1 |
| P61666 | 2.47e-11 | 984 | 1069 | 5 | 90 | DNA mismatch repair protein MutS OS=Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) OX=882 GN=mutS PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000072 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |