logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000081_01303

You are here: Home > Sequence: MGYG000000081_01303

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Corynebacterium propinquum
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium propinquum
CAZyme ID MGYG000000081_01303
CAZy Family AA3
CAZyme Description Oxygen-dependent choline dehydrogenase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
600 MGYG000000081_5|CGC1 67271.39 5.39
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000081 2502902 Isolate United Kingdom Europe
Gene Location Start: 101288;  End: 103090  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000081_01303.

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA3 33 561 3.7e-159 0.9894366197183099

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK02106 PRK02106 0.0 48 578 22 549
choline dehydrogenase; Validated
TIGR01810 betA 0.0 49 566 17 532
choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions]
COG2303 BetA 5.28e-174 48 566 24 539
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
TIGR03970 Rv0697 6.16e-92 49 560 18 486
dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function.
pfam00732 GMC_oxred_N 6.66e-52 102 327 15 218
GMC oxidoreductase. This family of proteins bind FAD as a cofactor.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CAB3230510.1 3.14e-162 35 574 28 569
AWP09430.1 2.00e-156 35 575 23 565
ANI26486.1 8.10e-155 35 575 74 616
CAG5086058.1 1.24e-146 33 576 16 579
CAG5089487.1 1.35e-144 7 576 2 574

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3LJP_A 1.83e-87 27 561 9 527
ChainA, Choline oxidase [Arthrobacter globiformis],3LJP_B Chain B, Choline oxidase [Arthrobacter globiformis]
2JBV_A 7.09e-87 27 561 9 527
Crystalstructure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],2JBV_B Crystal structure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],4MJW_A Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis],4MJW_B Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis]
3NNE_A 7.09e-87 27 561 9 527
Crystalstructure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_B Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_C Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_D Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_E Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_F Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_G Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_H Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis]
5NCC_A 5.24e-77 18 571 10 587
Structureof Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_B Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_C Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_D Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_E Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_F Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis]
7AV4_AAA 1.96e-76 18 571 70 647
ChainAAA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q2YWJ5 1.08e-245 33 577 9 553
Oxygen-dependent choline dehydrogenase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=betA PE=3 SV=1
Q5HCU1 1.08e-245 33 577 9 553
Oxygen-dependent choline dehydrogenase OS=Staphylococcus aureus (strain COL) OX=93062 GN=betA PE=3 SV=1
P60336 1.08e-245 33 577 9 553
Oxygen-dependent choline dehydrogenase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) OX=158878 GN=betA PE=3 SV=1
P60337 1.08e-245 33 577 9 553
Oxygen-dependent choline dehydrogenase OS=Staphylococcus aureus (strain N315) OX=158879 GN=betA PE=1 SV=1
Q6GDJ1 1.08e-245 33 577 9 553
Oxygen-dependent choline dehydrogenase OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=betA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000029 0.000004 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000081_01303.