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CAZyme Information: MGYG000000091_00219

You are here: Home > Sequence: MGYG000000091_00219

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Achromobacter xylosoxidans
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; Achromobacter; Achromobacter xylosoxidans
CAZyme ID MGYG000000091_00219
CAZy Family CBM32
CAZyme Description Non-hemolytic phospholipase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
716 MGYG000000091_1|CGC2 77346.7 7.3262
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000091 6684283 Isolate United Kingdom Europe
Gene Location Start: 254679;  End: 256829  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000091_00219.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR03396 PC_PLC 0.0 3 705 1 689
phospholipase C, phosphocholine-specific, Pseudomonas-type. Members of this protein family are bacterial, phosphatidylcholine-hydrolyzing phospholipase C enzymes, with a characteristic domain architecture as found in hemolytyic (PlcH) and nonhemolytic (PlcN) secreted enzymes of Pseudomonas aeruginosa. PlcH hydrolyzes phosphatidylcholine to diacylglycerol and phosphocholine, but unlike PlcN can also hydrolyze sphingomyelin to ceramide ((N-acylsphingosine)) and phosphocholine. Members of this family share the twin-arginine signal sequence for Sec-independent transport across the plasma membrane. PlcH is secreted as a heterodimer with a small chaperone, PlcR, encoded immediately downstream. [Cellular processes, Pathogenesis]
COG3511 PlcC 1.33e-179 3 557 5 527
Phospholipase C [Cell wall/membrane/envelope biogenesis].
cd16014 PLC 6.94e-128 46 446 1 287
non-hemolytic phospholipase C. Nonhemolytic Phospholipases C is produced by pathogenic bacterial. The toxic phospholipases C can interact with eukaryotic cell membranes and hydrolyze phosphatidylcholine and sphingomyelin, leading to cell lysis.
pfam04185 Phosphoesterase 6.42e-116 46 445 1 347
Phosphoesterase family. This family includes both bacterial phospholipase C enzymes EC:3.1.4.3, but also eukaryotic acid phosphatases EC:3.1.3.2.
cd16013 AcpA 1.61e-71 44 446 1 367
acid phosphatase A. Acid phosphatase A catalyzes the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at low pH. AcpA hydrolyzes a variety of substrates, including p-nitrophenylphosphate (pNPP), p-nitrophenylphosphorylcholine (pNPPC), peptides containing phosphotyrosine, inositol phosphates, AMP, ATP, fructose 1,6-bisphosphate, glucose and fructose 6-phosphates, NADP, and ribose 5-phosphate. AcpA is distinct from histidine ACPs and purple ACPs, as well as class A, B, and C bacterial nonspecific ACPs.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QKW17792.1 8.34e-161 3 704 10 674
ANN20098.1 2.09e-147 15 705 10 699
QWF84028.1 3.33e-145 4 705 3 698
SDU45390.1 1.35e-144 15 716 10 709
QNF45407.1 1.90e-144 15 716 10 709

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D1G_A 1.66e-11 36 467 25 470
ChainA, acid phosphatase [Francisella tularensis subsp. novicida],2D1G_B Chain B, acid phosphatase [Francisella tularensis subsp. novicida]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P15713 1.29e-227 2 705 4 686
Non-hemolytic phospholipase C OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=plcN PE=3 SV=2
Q9RGS8 5.84e-179 2 702 4 695
Non-hemolytic phospholipase C OS=Burkholderia pseudomallei (strain K96243) OX=272560 GN=plcN PE=1 SV=2
P06200 4.95e-138 4 704 9 725
Hemolytic phospholipase C OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=plcH PE=3 SV=2
P9WIA8 1.42e-77 3 470 10 453
Phospholipase C D OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=plcD PE=1 SV=1
P0A5R9 1.42e-77 3 470 10 453
Phospholipase C D OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=plcD PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as TAT

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000000 0.000000 0.000000 0.999999 0.000003 0.000000

TMHMM  Annotations      download full data without filtering help

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