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CAZyme Information: MGYG000000104_02393

You are here: Home > Sequence: MGYG000000104_02393

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Clostridium cuniculi
Lineage Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium cuniculi
CAZyme ID MGYG000000104_02393
CAZy Family CBM32
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1156 MGYG000000104_16|CGC1 125378.44 4.4006
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000104 3679160 Isolate Canada North America
Gene Location Start: 33951;  End: 37421  Strand: -

Full Sequence      Download help

MKRKKIAVLI  TASAIAFNTV  SSPSYVNVLA  HEMQEFKNLI  IEEEIPQNQM  TAVATSSQSG60
EDGSKAIDGD  LNTMWHTPWS  ITDNSKLPQS  LTIDLGGSNN  VSSIKVSPRI  SQTNGIITKY120
EIYAINGDEE  NLVATGNWNL  DNLAKVVDFD  EPVKAEKIKI  TAVEAGAGFA  SIAEVNIYRV180
KEGVEKVASY  ENKKISNNNG  IDISSDVESL  KNLESGTIIS  RFDTSKGDIQ  SLISIGNNTV240
ANGHFHLYVA  DNTVGFEVRN  QSGNVATGKA  SAVLNKGINT  VALKVTSGEG  YKIFINGKLA300
GEIKTTAATL  SAGVVGVNNV  FIGKTDRASG  NEYPFNGYID  FIDIYGEALS  DKYLIDITGQ360
TVLPSEEEIL  PEGMKTEPID  LFKPGDLGSQ  NFRIPALFTT  KDGTVIASID  VRNKGGADAP420
WNDIDSAIRR  KTLGGEWEEA  QKVIDYPNGA  SVIDTSLTQD  EETGRVFLLV  TTFPENYGFW480
QAEAGSGYTE  IDGVKYRSLY  DASENLYTIR  ESGNVYDSEG  NITNYNVNVN  TMELTKDNNV540
VGNVMTASCE  LKVYGTSYLS  LIYSDDDGAT  WSKPVDINSD  IKADWMKFLG  TGPGSGIQIK600
NGEYAGRIVF  PVYYTNGAGK  QSSAVIYSDD  HGETWNMGES  PNDGRDLGDG  SFGNSQTMTG660
GLELTECQAV  EMPNGQLKLF  MRNTGSYVRI  ATSFDGGATW  DSEVYEDTNL  PEPYCQLSVM720
NYSKKIDGQD  AIVFANPKGT  GRTNGTVRFG  IIKQNGTHSN  GEPRYEFEWK  YNKLVKAGTY780
AYSCLTELPN  GDIGLFYEGT  DNKEMSYIEM  SPEYIKFNYE  SSLEELVDPG  KIESIELLDG840
KNSYTPGDKI  TVKLSFDQAV  SLIGNKNLIL  NIGDSKIILN  PISKGNAREF  KFEGTLPTTL900
SEGTFNLVLE  CNNDIEILNT  VGKNTTLNGD  IELGNSITIN  KVIDKSDLVK  VIENAKNIIE960
NETDKYTESS  IDALKEAIAI  AEETIANEVA  TQEQVDSSYN  VLLRAYLSLR  LTPDKSLLEG1020
LIKEVSSIDL  SKYTAKSAEI  LEKALEDANK  VLNNEEATEK  EVNKALENLK  NAKNSLVASS1080
DSNSNTNSNQ  NSNSDLNANS  NSANSSKNNN  KDSSNSSTGN  STTGKLPQTG  TTGVVGTLIS1140
GVVTLLCGLG  LSRKKK1156

Enzyme Prediction      help

EC 3.2.1.18

CAZyme Signature Domains help

Created with Snap5711517323128934640446252057863569375180986792498210401098379809GH33192358CBM4054175CBM32
Family Start End Evalue family coverage
GH33 379 809 5.7e-99 0.9619883040935673
CBM40 192 358 7.4e-43 0.9664804469273743
CBM32 54 175 4.4e-18 0.9112903225806451

CDD Domains      download full data without filtering help

Created with Snap5711517323128934640446252057863569375180986792498210401098380808Sialidase_non-viral227801NanH184361Sialidase556795BNR_251175F5_F8_type_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.37e-85 380 808 2 333
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
COG4409 NanH 3.49e-31 227 801 86 703
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam02973 Sialidase 3.38e-27 184 361 1 188
Sialidase, N-terminal domain.
pfam13088 BNR_2 2.99e-17 556 795 79 280
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam00754 F5_F8_type_C 5.72e-16 51 175 1 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.

CAZyme Hits      help

Created with Snap571151732312893464044625205786356937518098679249821040109821069AYE33273.1|CBM32|CBM40|GH3321069QAS61444.1|CBM32|CBM40|GH3311156ATD57534.1|CBM32|CBM40|GH3311156QBJ75069.1|CBM32|CBM40|GH3311156ATD54786.1|CBM32|CBM40|GH33
Hit ID E-Value Query Start Query End Hit Start Hit End
AYE33273.1 0.0 2 1069 3 1087
QAS61444.1 0.0 2 1069 3 1087
ATD57534.1 0.0 1 1156 1 1299
QBJ75069.1 0.0 1 1156 1 1299
ATD54786.1 0.0 1 1156 1 1299

PDB Hits      download full data without filtering help

Created with Snap57115173231289346404462520578635693751809867924982104010983748165TSP_A3748162BF6_A3748162VK5_A2018171SLI_A3708203H72_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5TSP_A 1.30e-194 374 816 6 448
Crystalstructure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES [Clostridium perfringens ATCC 13124],5TSP_B Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES [Clostridium perfringens ATCC 13124]
2BF6_A 6.69e-194 374 816 5 447
AtomicResolution Structure of the bacterial sialidase NanI from Clostridium perfringens in complex with alpha-Sialic Acid (Neu5Ac). [Clostridium perfringens]
2VK5_A 7.44e-194 374 816 5 447
TheStructure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK6_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_B The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens]
1SLI_A 1.01e-94 201 817 22 667
LeechIntramolecular Trans-Sialidase Complexed With Dana [Macrobdella decora],1SLL_A Sialidase L From Leech Macrobdella Decora [Macrobdella decora],2SLI_A Leech Intramolecular Trans-Sialidase Complexed With 2,7- Anhydro-Neu5ac, The Reaction Product [Macrobdella decora],3SLI_A Leech Intramolecular Trans-Sialidase Complexed With 2,7- Anhydro-Neu5ac Prepared By Soaking With 3'-Sialyllactose [Macrobdella decora],4SLI_A Leech Intramolecular Trans-Sialidase Complexed With 2- Propenyl-Neu5ac, An Inactive Substrate Analogue [Macrobdella decora]
3H72_A 1.08e-85 370 820 1 471
Crystalstructure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with NANA [Streptococcus pneumoniae R6],3H72_B Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with NANA [Streptococcus pneumoniae R6],3H73_A Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with DANA [Streptococcus pneumoniae R6],3H73_B Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with DANA [Streptococcus pneumoniae R6]

Swiss-Prot Hits      download full data without filtering help

Created with Snap571151732312893464044625205786356937518098679249821040109821006sp|P29767|NANH_CLOSE125817sp|Q27701|NANL_MACDE182829sp|P62576|NANA_STRR6182829sp|P62575|NANA_STREE197811sp|Q54727|NANB_STRPN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P29767 2.11e-316 2 1006 3 1013
Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1
Q27701 5.70e-94 125 817 28 747
Anhydrosialidase OS=Macrobdella decora OX=6405 PE=1 SV=1
P62576 3.24e-93 182 829 116 796
Sialidase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=nanA PE=1 SV=1
P62575 3.24e-93 182 829 116 796
Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1
Q54727 7.73e-37 197 811 51 682
Sialidase B OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=nanB PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000301 0.999050 0.000169 0.000172 0.000153 0.000137

TMHMM  Annotations      download full data without filtering help

start end
7 29
1129 1151