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CAZyme Information: MGYG000000111_00133

You are here: Home > Sequence: MGYG000000111_00133

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Cutibacterium acnes
Lineage Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Cutibacterium; Cutibacterium acnes
CAZyme ID MGYG000000111_00133
CAZy Family GH84
CAZyme Description O-GlcNAcase NagJ
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
971 MGYG000000111_1|CGC3 104031.67 6.7914
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000111 2484103 Isolate Canada North America
Gene Location Start: 130771;  End: 133686  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.52

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH84 199 508 1.8e-100 0.9932203389830508
CBM32 674 798 2.2e-21 0.9435483870967742

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam07555 NAGidase 3.12e-148 199 507 1 293
beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam00754 F5_F8_type_C 5.05e-22 674 797 3 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
pfam02838 Glyco_hydro_20b 1.69e-21 52 192 2 123
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
cd00057 FA58C 2.37e-10 674 799 15 141
Substituted updates: Jan 31, 2002
smart00231 FA58C 2.10e-06 674 786 15 127
Coagulation factor 5/8 C-terminal domain, discoidin domain. Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALD69353.1 0.0 1 971 1 971
AER06669.1 0.0 30 971 1 942
QTF73146.1 0.0 13 917 10 920
QGH68398.1 1.19e-305 7 931 10 926
QJW35068.1 2.30e-296 52 917 47 912

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6PV5_A 4.37e-82 53 560 41 541
Structureof CpGH84B [Clostridium perfringens ATCC 13124]
2V5D_A 8.20e-82 51 785 13 716
Structureof a Family 84 Glycoside Hydrolase and a Family 32 Carbohydrate-Binding Module in Tandem from Clostridium perfringens. [Clostridium perfringens]
2CBI_A 1.99e-78 51 564 13 510
Structureof the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBI_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBJ_A Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2CBJ_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2V5C_A Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2V5C_B Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2VUR_A Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2VUR_B Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2X0Y_A Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens],2X0Y_B Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens]
5OXD_A 2.50e-78 51 564 15 512
Complexof a C. perfringens O-GlcNAcase with a fragment hit [Clostridium perfringens]
2J62_A 2.75e-78 51 564 13 510
Structureof a bacterial O-glcnacase in complex with glcnacstatin [Clostridium perfringens],2J62_B Structure of a bacterial O-glcnacase in complex with glcnacstatin [Clostridium perfringens],2WB5_A GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation [Clostridium perfringens],2WB5_B GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation [Clostridium perfringens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q0TR53 1.16e-80 11 785 3 746
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08 1.58e-80 11 785 3 746
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q89ZI2 1.19e-63 159 800 111 733
O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q2CEE3 2.27e-38 198 531 2 354
Protein O-GlcNAcase OS=Oceanicola granulosus (strain ATCC BAA-861 / DSM 15982 / KCTC 12143 / HTCC2516) OX=314256 GN=OG2516_04129 PE=1 SV=1
P26831 9.90e-34 158 799 142 794
Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000498 0.998538 0.000242 0.000270 0.000231 0.000180

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000111_00133.