CAZyme Information: MGYG000000113_00485

Basic Information

• Species: Streptococcus salivarius
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus salivarius
• CAZyme ID: MGYG000000113_00485
• CAZy Family: GH25
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
967	MGYG000000113_2|CGC6	104818.12	6.8285

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000113	2251845	Isolate	Canada	North America

• Gene Location: Start: 251522; End: 254425 Strand: +

Full Sequence      

MRTKDFIYYASAAVLLAVTTQVAQADEVATQTPSVTEGNQYQPATAAEIFGGEAALPATP
SSTVSAPVATSELAKPSAPAVSTSLAPESSEAVTTAASTSVANSTVAVASTSVTSSVVSS
ESATASTSATSSETSNSAVATPAKLTNSTDVPSPTLKVQPKTFIDVSSHNGDISVDDYRA
LARQGVGGVVVKLTEDTWYNNPKAPSQVRNAQIAGLQVSTYHFSRYTTEEEARAEARFYI
QAAQKLNLPKSTVMVNDFEDSKMLPNINRNTQAWVNEMRKHGYNNLMFYTSASWLDENNI
GYRGPVSTSQFGIENFWVAQYPSTTLTATSAKNMRYNAKTGAWQFSATANLLPGKHVFDH
SVDYTGRFTANASAEVDATQGDLSGTISIVNINPTLGSFDVVISNVKAPNGVETVSVPIW
SEINGQDDIIWYTANRQNNGTYTVNVKASAHKNSTGLYNVHLYYIQKDGQLTGVGGTTTQ
VFIGKTPEQLKPKASFAIENNNAKAGTFDAVITNISAPLGVKEVLVPSWSLENGQDDLIW
HKATKQNDGSYRVTIKASEHKGNKGNYRADAYIVDNANNRHYIAEKVVSVDYARPSGVLT
IENNNTAAGTFDAVVRNIVAPIGLKEVLVPSWSLAGGQDDLIWHKATRQADGSYRVTIKA
TDHKNSTGKYRADAYIVDDSNKRFYLTEKVVEVTQTRPSASLVIENNNADLGTFDAVIRN
IVAPNGVKEVLVPSWSLVNGQDDLVWHKASRQSDGSYRVTIKSSEHKNSLGNYRADVYIV
DNANQRHYVTEAIVDVKHNKPVGTISVVNNNKDTGTFDVIISDVYSPKGVRTVQVPIWSA
KDGQDDIRWYEAKRQVNGTYTVNVQATNHKNSTGLYNIHLYYILNDGSQVGVGGTTTTLE
FRNAKTKTQTYITNVNSEAGSFTVVVDQAPQGRQIKNIRVAVWSESNQGNLSWYNTAPTG
THTEINV

Enzyme Prediction     

No EC number prediction in MGYG000000113_00485.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH25	164	350	9.7e-40	0.9717514124293786

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06522	GH25_AtlA-like	1.80e-77	161	364	1	192	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml autolysins from Streptococcus mutans which have a C-terminal glycosyl hydrolase family 25 (GH25) catalytic domain as well as six tandem N-terminal repeats of the GBS (group B Streptococcus) Bsp-like peptidoglycan-binding domain. Other members of this family have one or more C-terminal peptidoglycan-binding domain(s) (SH3 or LysM) in addition to the GH25 domain.
pfam01183	Glyco_hydro_25	3.45e-37	164	351	1	177	Glycosyl hydrolases family 25.
pfam08481	GBS_Bsp-like	1.45e-32	807	895	1	89	GBS Bsp-like repeat. This domain is found as a repeat in a number of Streptococcus proteins including some hypothetical proteins and Bsp. Bsp is a protein of group B Streptococcus (GBS) which might control cell morphology.
pfam08481	GBS_Bsp-like	1.53e-31	389	477	1	89	GBS Bsp-like repeat. This domain is found as a repeat in a number of Streptococcus proteins including some hypothetical proteins and Bsp. Bsp is a protein of group B Streptococcus (GBS) which might control cell morphology.
cd00599	GH25_muramidase	4.71e-27	163	351	2	174	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ARC22445.1	0.0	1	967	1	967
ALR79927.1	0.0	1	967	1	967
QMI50992.1	0.0	1	967	1	967
ARI57272.1	0.0	1	967	1	967
CCB95385.1	0.0	1	967	1	967

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000294	0.998861	0.000276	0.000185	0.000185	0.000153

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000113_00485.