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CAZyme Information: MGYG000000119_02085

You are here: Home > Sequence: MGYG000000119_02085

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Blautia sp000432195
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia; Blautia sp000432195
CAZyme ID MGYG000000119_02085
CAZy Family GH67
CAZyme Description Xylan alpha-(1->2)-glucuronosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
660 MGYG000000119_12|CGC2 76034.86 5.1385
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000119 3510293 Isolate Canada North America
Gene Location Start: 66815;  End: 68797  Strand: +

Full Sequence      Download help

MEFEKAWLTY  RRNQQLAVLW  STNSVYSNFQ  GTIAKNAVQE  LRIAAQEILG  CSMIETQCQK60
EAGVLLLLDE  NHQVGKEGYE  IYQEDGKLFI  TSGGEAGILY  GVFHLARILQ  CASKELELPV120
KKVPDSPLRM  LNHWDNMDGS  IERGYSGESF  FFQKNEILVN  DRTRAYARLA  ASVGINGVVI180
NNVNVKERAT  WLIDEVFQKE  LKEMSDIFAS  YGIRLFLSLN  FAAPMELGGL  DHADPCSEDV240
KTWWKEKMKE  LYTRLPNLGG  FLVKADSEGR  PGPFTYGRTH  ADGANMLAEA  VKPYDGLIIW300
RCFVYNCQQD  WRDRKTDRAR  SGYDNFKPLD  GQFFDNVILQ  VKNGPMDFQV  REPISPLLGG360
MEHTNEMLEV  QIAQEYTGQQ  RHVCYLIPMF  KEILGFHTYC  NKELDTVEDI  VTGRTMGNHN420
CGMAAVANTG  NDENWTGHDL  AAANFYGFGR  LSFDTSLSAE  EIAQEWIYCT  FGQDKEVLEK480
IEKILMMSWP  AYEKYTSPLG  IGWMVNPNYH  YGPNVDGYEY  DRWGTYHRAD  HLGMGVERGH540
EGTGYTQQYR  EPNASMYDNI  ETCPEELLLF  FHYIPYTYPL  RTGKTLIQHI  YDTHFEGAED600
VEEMATLWES  LEAKIPSKVF  QRVQKRLEHQ  KGHSKEWRDQ  INSYFYRKSM  IPDEQNRKIY660
660

Enzyme Prediction      help

EC 3.2.1.139 3.2.1.131

CAZyme Signature Domains help

Created with Snap3366991321651982312642973303633964294624955285615946275657GH67
Family Start End Evalue family coverage
GH67 5 657 4.4e-278 0.9940209267563528

CDD Domains      download full data without filtering help

Created with Snap33669913216519823126429733036339642946249552856159462762660AguA2117434Glyco_hydro_67M436658Glyco_hydro_67C6105Glyco_hydro_67N
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3661 AguA2 0.0 62 660 81 682
Alpha-glucuronidase [Carbohydrate transport and metabolism].
pfam07488 Glyco_hydro_67M 0.0 117 434 10 324
Glycosyl hydrolase family 67 middle domain. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the central catalytic domain of alpha-glucuronidase.
pfam07477 Glyco_hydro_67C 1.19e-142 436 658 1 223
Glycosyl hydrolase family 67 C-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the C terminal region of alpha-glucuronidase which is mainly alpha-helical. It wraps around the catalytic domain (pfam07488), making additional interactions both with the N-terminal domain (pfam03648) of its parent monomer and also forming the majority of the dimer-surface with the equivalent C-terminal domain of the other monomer of the dimer.
pfam03648 Glyco_hydro_67N 0.006 6 105 1 120
Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits      help

Created with Snap3366991321651982312642973303633964294624955285615946272660QJU15649.1|GH672660QQQ91839.1|GH672660ANU78479.1|GH672660ASU31294.1|GH671660QHQ61647.1|GH67
Hit ID E-Value Query Start Query End Hit Start Hit End
QJU15649.1 0.0 2 660 4 661
QQQ91839.1 0.0 2 660 4 661
ANU78479.1 0.0 2 660 11 668
ASU31294.1 0.0 2 660 4 661
QHQ61647.1 0.0 1 660 1 660

PDB Hits      download full data without filtering help

Created with Snap33669913216519823126429733036339642946249552856159462736601K9D_A36601MQP_A36601MQR_A36601K9E_A746451GQI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1K9D_A 1.60e-261 3 660 5 678
The1.7 A crystal structure of alpha-D-glucuronidase, a family-67 glycoside hydrolase from Bacillus stearothermophilus T-1 [Geobacillus stearothermophilus],1L8N_A The 1.5A crystal structure of alpha-D-glucuronidase from Bacillus stearothermophilus T-1, complexed with 4-O-methyl-glucuronic acid and xylotriose [Geobacillus stearothermophilus],1MQQ_A THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-1 COMPLEXED WITH GLUCURONIC ACID [Geobacillus stearothermophilus]
1MQP_A 4.56e-261 3 660 5 678
TheCrystal Structure Of Alpha-D-Glucuronidase From Bacillus Stearothermophilus T-6 [Geobacillus stearothermophilus]
1MQR_A 1.30e-260 3 660 5 678
ChainA, ALPHA-D-GLUCURONIDASE [Geobacillus stearothermophilus]
1K9E_A 2.61e-260 3 660 5 678
ChainA, alpha-D-glucuronidase [Geobacillus stearothermophilus],1K9F_A Chain A, alpha-D-glucuronidase [Geobacillus stearothermophilus]
1GQI_A 2.35e-146 74 645 92 663
Structureof Pseudomonas cellulosa alpha-D-glucuronidase [Cellvibrio japonicus],1GQI_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase [Cellvibrio japonicus],1GQJ_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with xylobiose [Cellvibrio japonicus],1GQJ_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with xylobiose [Cellvibrio japonicus],1GQK_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid [Cellvibrio japonicus],1GQK_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid [Cellvibrio japonicus],1GQL_A Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid and xylotriose [Cellvibrio japonicus],1GQL_B Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid and xylotriose [Cellvibrio japonicus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap3366991321651982312642973303633964294624955285615946273660sp|Q09LY5|AGUA_GEOSE68660sp|P96105|AGUA_THEMA37657sp|B0Y2K1|AGUA_ASPFC37657sp|Q4WW45|AGUA_ASPFU73657sp|A1CC12|AGUA_ASPCL
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q09LY5 2.49e-260 3 660 5 678
Xylan alpha-(1->2)-glucuronosidase OS=Geobacillus stearothermophilus OX=1422 GN=aguA PE=1 SV=1
P96105 2.99e-250 68 660 79 673
Xylan alpha-(1->2)-glucuronosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=aguA PE=1 SV=2
B0Y2K1 2.03e-170 37 657 60 692
Probable alpha-glucuronidase A OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=aguA PE=3 SV=1
Q4WW45 2.03e-170 37 657 60 692
Probable alpha-glucuronidase A OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=aguA PE=3 SV=1
A1CC12 3.20e-169 73 657 109 692
Probable alpha-glucuronidase A OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=aguA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000068 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000119_02085.