CAZyme Information: MGYG000000135_03082

Basic Information

• Species: Murimonas intestini
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Murimonas; Murimonas intestini
• CAZyme ID: MGYG000000135_03082
• CAZy Family: GH29
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
339	MGYG000000135_6|CGC10	38946.08	5.1325

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000135	5745007	Isolate	Canada	North America

• Gene Location: Start: 287236; End: 288255 Strand: -

Full Sequence      

MDLRKWFKEAQYGMMVHWGLYSLLAGEWKDKRSGCYSEWIQAHCDIPNAEYAKLANAFNP
VFFNADEWVKFAKDCGMKYFVVTTKHHDGFAMFRTKVDKYNIVDATPFGRDFVGEIGEAC
YKHGLKMGLYYSQDLDWHEEHGGGYKSGHIPCQGTAWCNNWDFPNDDKKDFNICFNNKIY
PQVEELLRNYGDLCLIWFDMPMTLEEAQSRKLYEAIKKYQPECLINSRLGNGVYDYVSLG
DNEIPDSMPENVELDPEAMNGIEGFKPSPYGLYETAATINNSWGYCAWDQNWKSAEQIAA
NKKKLNGMGINYLLNVGPDGLGRIPLASREILKKVAETF

Enzyme Prediction     

No EC number prediction in MGYG000000135_03082.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH29	5	336	3.9e-86	0.8410404624277457

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam01120	Alpha_L_fucos	2.70e-75	3	337	18	326	Alpha-L-fucosidase.
smart00812	Alpha_L_fucos	1.85e-69	5	337	21	328	Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.
COG3669	AfuC	2.96e-33	17	338	1	311	Alpha-L-fucosidase [Carbohydrate transport and metabolism].
pfam14871	GHL6	5.07e-04	64	200	1	135	Hypothetical glycosyl hydrolase 6. GHL6 is a family of hypothetical glycoside hydrolases.
PLN02778	PLN02778	0.005	116	265	94	218	3,5-epimerase/4-reductase

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUO31265.1	1.18e-160	2	335	3	351
ALB28421.1	1.02e-159	5	337	6	336
AYE37750.1	8.50e-157	5	337	6	336
QPC18107.1	1.34e-156	6	332	7	332
QGV19506.1	1.90e-156	6	332	7	332

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6O18_A	2.92e-157	6	332	7	332	ChainA, AlfC [Lacticaseibacillus casei],6O18_B Chain B, AlfC [Lacticaseibacillus casei],6O18_C Chain C, AlfC [Lacticaseibacillus casei],6O18_D Chain D, AlfC [Lacticaseibacillus casei],6O1A_A Chain A, AlfC [Lacticaseibacillus casei],6O1A_B Chain B, AlfC [Lacticaseibacillus casei],6O1A_C Chain C, AlfC [Lacticaseibacillus casei],6O1A_D Chain D, AlfC [Lacticaseibacillus casei]
6O1I_A	2.39e-156	6	332	7	332	ChainA, AlfC [Lacticaseibacillus casei],6O1I_B Chain B, AlfC [Lacticaseibacillus casei],6O1I_C Chain C, AlfC [Lacticaseibacillus casei],6O1I_D Chain D, AlfC [Lacticaseibacillus casei]
6O1C_A	4.81e-156	6	332	7	332	ChainA, AlfC [Lacticaseibacillus casei],6O1C_B Chain B, AlfC [Lacticaseibacillus casei],6O1C_C Chain C, AlfC [Lacticaseibacillus casei],6O1C_D Chain D, AlfC [Lacticaseibacillus casei],6O1C_E Chain E, AlfC [Lacticaseibacillus casei],6O1C_F Chain F, AlfC [Lacticaseibacillus casei],6O1C_G Chain G, AlfC [Lacticaseibacillus casei],6O1C_H Chain H, AlfC [Lacticaseibacillus casei],6OHE_A Chain A, AlfC [Lacticaseibacillus casei],6OHE_B Chain B, AlfC [Lacticaseibacillus casei],6OHE_C Chain C, AlfC [Lacticaseibacillus casei],6OHE_D Chain D, AlfC [Lacticaseibacillus casei]
6O1J_A	4.81e-156	6	332	7	332	ChainA, AlfC [Lacticaseibacillus casei],6O1J_B Chain B, AlfC [Lacticaseibacillus casei],6O1J_C Chain C, AlfC [Lacticaseibacillus casei],6O1J_D Chain D, AlfC [Lacticaseibacillus casei],6O1J_E Chain E, AlfC [Lacticaseibacillus casei],6O1J_F Chain F, AlfC [Lacticaseibacillus casei],6O1J_G Chain G, AlfC [Lacticaseibacillus casei],6O1J_H Chain H, AlfC [Lacticaseibacillus casei]
6GN6_A	1.09e-57	5	335	32	340	Alpha-L-fucosidaseisoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_B Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_C Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_D Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_E Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_F Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q99LJ1	4.63e-22	3	332	35	342	Tissue alpha-L-fucosidase OS=Mus musculus OX=10090 GN=Fuca1 PE=1 SV=1
Q2KIM0	9.46e-22	3	332	52	359	Tissue alpha-L-fucosidase OS=Bos taurus OX=9913 GN=FUCA1 PE=2 SV=1
P17164	1.69e-21	3	332	45	352	Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1
Q60HF8	1.48e-20	3	332	51	358	Tissue alpha-L-fucosidase OS=Macaca fascicularis OX=9541 GN=FUCA1 PE=2 SV=1
P04066	2.69e-20	3	332	49	356	Tissue alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA1 PE=1 SV=4

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000082	0.000003	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000135_03082.