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CAZyme Information: MGYG000000140_00661

You are here: Home > Sequence: MGYG000000140_00661

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UMGS1375 sp900066615
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS1375; UMGS1375 sp900066615
CAZyme ID MGYG000000140_00661
CAZy Family GH84
CAZyme Description Hyaluronoglucosaminidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1604 178604.82 5.7113
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000140 3539979 Isolate United Kingdom Europe
Gene Location Start: 102557;  End: 107371  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.35 3.2.1.52

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH84 181 488 7.6e-93 0.9796610169491525

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam07555 NAGidase 1.26e-116 181 490 1 292
beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838 Glyco_hydro_20b 9.51e-16 36 174 1 123
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
sd00036 LRR_3 1.56e-15 1511 1580 1 68
leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.
sd00036 LRR_3 1.42e-13 1511 1582 47 116
leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.
sd00036 LRR_3 1.49e-13 1501 1569 63 126
leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AXH51290.1 0.0 37 1434 39 1494
ALG47574.1 0.0 37 1434 39 1494
AQW22579.1 0.0 37 1434 39 1494
ATD49893.1 0.0 37 1434 39 1494
AOY52617.1 0.0 37 1434 39 1494

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6PV4_A 7.63e-196 37 654 32 653
Structureof CpGH84A [Clostridium perfringens ATCC 13124],6PV4_B Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_C Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_D Structure of CpGH84A [Clostridium perfringens ATCC 13124]
6PWI_A 1.97e-105 36 647 33 626
Structureof CpGH84D [Clostridium perfringens ATCC 13124],6PWI_B Structure of CpGH84D [Clostridium perfringens ATCC 13124]
6PV5_A 4.77e-65 36 609 39 597
Structureof CpGH84B [Clostridium perfringens ATCC 13124]
2XPK_A 1.81e-57 41 550 18 505
Cell-penetrant,nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens],2XPK_B Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens]
7KHV_A 8.11e-57 41 550 18 505
CpOGAIN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_B CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_C CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_D CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_E CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_F CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P26831 0.0 37 1434 39 1494
Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
Q0TR53 3.00e-54 41 690 48 655
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08 3.98e-54 41 690 48 655
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q89ZI2 2.30e-52 123 607 97 556
O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
O60502 7.43e-23 182 452 63 331
Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000597 0.980658 0.018041 0.000257 0.000232 0.000213

TMHMM  Annotations      download full data without filtering help

start end
12 31