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CAZyme Information: MGYG000000140_01835
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS1375 sp900066615 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS1375; UMGS1375 sp900066615 | |||||||||||
| CAZyme ID | MGYG000000140_01835 | |||||||||||
| CAZy Family | GH29 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 130654; End: 134961 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH29 | 274 | 656 | 3.3e-57 | 0.9364161849710982 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG3669 | AfuC | 4.64e-54 | 288 | 797 | 3 | 430 | Alpha-L-fucosidase [Carbohydrate transport and metabolism]. |
| smart00812 | Alpha_L_fucos | 1.87e-24 | 302 | 653 | 22 | 328 | Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. |
| pfam01120 | Alpha_L_fucos | 1.98e-24 | 302 | 653 | 48 | 326 | Alpha-L-fucosidase. |
| COG5492 | YjdB | 6.65e-19 | 185 | 310 | 172 | 299 | Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction only]. |
| COG5492 | YjdB | 1.77e-16 | 1094 | 1197 | 158 | 261 | Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction only]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SLK22631.1 | 5.10e-161 | 289 | 1066 | 47 | 805 |
| QBJ76368.1 | 5.10e-161 | 289 | 1066 | 47 | 805 |
| ATD54107.1 | 5.10e-161 | 289 | 1066 | 47 | 805 |
| QUY65387.1 | 3.38e-157 | 288 | 1090 | 58 | 841 |
| PLT74914.1 | 3.45e-157 | 283 | 1029 | 53 | 772 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6TR3_A | 1.32e-143 | 283 | 835 | 15 | 544 | Ruminococcusgnavus GH29 fucosidase E1_10125 in complex with fucose [[Ruminococcus] gnavus E1] |
| 6TR4_A | 1.88e-142 | 283 | 835 | 15 | 544 | Ruminococcusgnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1],6TR4_B Ruminococcus gnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1] |
| 6ORG_A | 3.73e-86 | 290 | 798 | 5 | 449 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORG_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
| 6OR4_A | 4.41e-85 | 290 | 798 | 5 | 449 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6OR4_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_A Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
| 6ORF_A | 4.54e-85 | 290 | 798 | 5 | 449 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORF_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8GW72 | 9.63e-72 | 296 | 797 | 38 | 477 | Alpha-L-fucosidase 1 OS=Arabidopsis thaliana OX=3702 GN=FUC1 PE=1 SV=2 |
| Q7XUR3 | 1.64e-67 | 296 | 823 | 40 | 500 | Putative alpha-L-fucosidase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os04g0560400 PE=3 SV=2 |
| Q5RFI5 | 2.90e-07 | 302 | 656 | 74 | 359 | Plasma alpha-L-fucosidase OS=Pongo abelii OX=9601 GN=FUCA2 PE=2 SV=1 |
| P49713 | 5.22e-07 | 295 | 417 | 19 | 169 | Putative alpha-L-fucosidase OS=Caenorhabditis elegans OX=6239 GN=W03G11.3 PE=3 SV=2 |
| Q9BTY2 | 1.53e-06 | 302 | 656 | 76 | 361 | Plasma alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA2 PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000332 | 0.998839 | 0.000195 | 0.000234 | 0.000179 | 0.000149 |