CAZyme Information: MGYG000000140_02884

Basic Information

• Species: UMGS1375 sp900066615
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UMGS1375; UMGS1375 sp900066615
• CAZyme ID: MGYG000000140_02884
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
981	MGYG000000140_23|CGC1	104593.07	4.3775

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000140	3539979	Isolate	United Kingdom	Europe

• Gene Location: Start: 7730; End: 10675 Strand: +

Full Sequence      

MKKNTLKRFMASAMTAVMCVSSLGTLAVNAAPADPAAETSVVDNLMSKMTLRQKIAQMMM
PDFRKWQTESDSGQKNFQVMNDEVAQIIKDYDFGGVILFAENVAQTDQTLKLTTDLQEAA
TGGTDGSNIPLLLTIDQEGGIVYRLGSGTALPGNMALGATRSTDAATQSGEVIGRELSAL
GINVDFAPVSDVNSNPSNPVIGLRSYGSDPELVGSMATAAMKGMQKYNIATAAKHFPGHG
DTATDSHTGLPCVDKSLDELRQCELVPFQKMIDNGVDMLMTAHIQYPQVEKETAISKKDG
SEIRLPATLSKTILTDLVRNEMHYDGIIVTDALNMDAISQNFGETDACIRAIKAGVDICL
MPTILRSKADMPKMDAILDGVEAAVNSGEISVDRINESVKRILSLKEKRGILNYTSDTRT
YEEKLAVANKQVGSEQNRDIERNISAQAVTVIKNNDNILPLKPQAGQKVLLLGAYNNETP
GLALGMRRVIADHIISGKVDYETFRYTSANLDQVKQKIDDTDYVIVISEVSTNFSNWLTT
QPTAITEYAKAQGKKSIVMSISKPYDVANYADSDAIVAVYGSKGMDPTEALKPDNAFGPN
IIAGVEVIFGRFAASGKLPVNVPVIENGQMTSDIKYAFGYGLTYDAVEPSSYYAVENSLL
NFYNTWKDADLSVYTADSAAALKSALTAAKAVLDKSNASITEMDSAVSALVDAVNNLAYG
VQKTHLNVAIVAADKLLERAADYENTEDLTAALTAAKAVYANTSATQTEVDRAASTLLDA
LAAMAERADLAALKKLVASAGGLEEKDFTSDSYKDLKDAMDAAKDVIDDLNRTPEAIGKA
YADIITAITNLERVGNKAALVAVIAKAEAIVAAKDSYVSSTLNGLEEALAAGKAVNDNPD
ALQDAINNAVTLLTEKVANVRLLGDVNNDGSVTTDDSALLLRSAAELDTLDDAATVSADM
NQDGIADTSDAVLILQTAAEF

Enzyme Prediction     

No EC number prediction in MGYG000000140_02884.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	127	361	2.2e-68	0.9675925925925926

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00933	Glyco_hydro_3	1.96e-103	50	405	1	316	Glycosyl hydrolase family 3 N terminal domain.
COG1472	BglX	2.32e-100	49	481	1	369	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
PRK05337	PRK05337	2.87e-53	94	361	27	279	beta-hexosaminidase; Provisional
PRK15098	PRK15098	1.46e-24	1	644	1	648	beta-glucosidase BglX.
pfam01915	Glyco_hydro_3_C	1.66e-09	449	644	1	216	Glycosyl hydrolase family 3 C-terminal domain. This domain is involved in catalysis and may be involved in binding beta-glucan. This domain is found associated with pfam00933.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SQG30206.1	3.12e-239	31	644	122	738
SQF34679.1	8.81e-239	20	644	111	738
QLB52351.1	1.29e-238	20	644	112	739
ABN44479.1	2.04e-237	21	644	113	739
QKQ43942.1	2.18e-237	20	644	114	741

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3BMX_A	3.45e-168	43	649	36	641	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	8.28e-168	43	649	10	615	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	2.32e-167	43	649	40	645	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
6K5J_A	1.19e-86	49	454	11	378	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
4ZM6_A	1.47e-82	84	627	30	532	Aunique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432],4ZM6_B A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	1.89e-167	43	649	36	641	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	1.30e-94	49	622	16	596	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
Q7WUL3	1.91e-42	94	582	58	529	Beta-N-acetylglucosaminidase/beta-glucosidase OS=Cellulomonas fimi OX=1708 GN=nag3 PE=1 SV=1
L7N6B0	4.67e-40	87	406	82	380	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	1.16e-39	87	406	82	380	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000279	0.998961	0.000186	0.000229	0.000179	0.000145

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000140_02884.