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CAZyme Information: MGYG000000145_03593

You are here: Home > Sequence: MGYG000000145_03593

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Lacrimispora sp902363735
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lacrimispora; Lacrimispora sp902363735
CAZyme ID MGYG000000145_03593
CAZy Family GH18
CAZyme Description Spore germination protein YaaH
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
430 MGYG000000145_10|CGC1 48901.05 4.5213
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000145 4646417 Isolate United Kingdom Europe
Gene Location Start: 79586;  End: 80878  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000145_03593.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 94 407 2.9e-23 0.847972972972973

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3858 YaaH 1.11e-78 1 422 1 422
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
cd02874 GH18_CFLE_spore_hydrolase 6.23e-71 105 418 1 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
smart00636 Glyco_18 1.88e-13 128 407 26 331
Glyco_18 domain.
cd02875 GH18_chitobiase 4.18e-11 180 407 85 336
Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes. Chitobiase can only do so if the asparagine that joins the oligosaccharide to protein is previously removed by a glycosylasparaginase. Chitobiase is therefore the final step in the lysosomal degradation of the protein/carbohydrate linkage component of asparagine-linked glycoproteins. The catalytic domain of chitobiase is an eight-stranded alpha/beta barrel fold similar to that of other family 18 glycosyl hydrolases such as hevamine and chitotriosidase.
smart00257 LysM 1.65e-10 3 46 1 44
Lysin motif.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SEU00635.1 8.58e-187 1 427 1 427
SET56373.1 2.82e-186 1 426 1 426
ADL06658.1 4.65e-184 1 426 1 426
QRV19272.1 4.65e-184 1 426 1 426
SET68115.1 1.30e-182 1 427 1 427

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4S3K_A 3.66e-51 3 426 6 431
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
4S3J_A 1.92e-48 6 420 8 424
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
3CZ8_A 1.85e-41 126 407 31 308
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O05495 1.08e-48 1 417 1 411
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P0DPJ9 7.09e-48 6 420 7 423
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
Q9K3E4 7.26e-47 6 420 7 423
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
P37531 1.08e-43 1 422 1 423
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
O32258 1.87e-12 136 415 60 336
Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000048 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000145_03593.